| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the ebselen-2717 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADD2 | adducin 2 (beta) |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit |
| APOL3 | apolipoprotein L, 3 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATP9A | ATPase, class II, type 9A |
| AURKA | aurora kinase A |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta |
| CCDC81 | coiled-coil domain containing 81 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CEP41 | centrosomal protein 41kDa |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| CLTA | clathrin, light chain A |
| COLEC10 | collectin sub-family member 10 (C-type lectin) |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNMBP | dynamin binding protein |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DUSP7 | dual specificity phosphatase 7 |
| ETV7 | ets variant 7 |
| FAS | Fas cell surface death receptor |
| FBRS | fibrosin |
| FGF4 | fibroblast growth factor 4 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FOXP3 | forkhead box P3 |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HMOX1 | heme oxygenase 1 |
| HNF1A | HNF1 homeobox A |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IGL | immunoglobulin lambda locus |
| IL17RC | interleukin 17 receptor C |
| ING2 | inhibitor of growth family, member 2 |
| IRF5 | interferon regulatory factor 5 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNJ4 | potassium channel, inwardly rectifying subfamily J, member 4 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LAMA4 | laminin, alpha 4 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
| MAMLD1 | mastermind-like domain containing 1 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MLANA | melan-A |
| MNMIP1 | manchette microtubule inner protein 1 |
| MOG | myelin oligodendrocyte glycoprotein |
| MPDZ | multiple PDZ domain protein |
| MS4A2 | membrane-spanning 4-domains, subfamily A, member 2 |
| MX1 | MX dynamin-like GTPase 1 |
| MYCNOS | MYCN opposite strand |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| PCGF2 | polycomb group ring finger 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| POU3F2 | POU class 3 homeobox 2 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) |
| PRKCE | protein kinase C, epsilon |
| PTPRJ | protein tyrosine phosphatase, receptor type, J |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RNF25 | ring finger protein 25 |
| SCRG1 | stimulator of chondrogenesis 1 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SFRP4 | secreted frizzled-related protein 4 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC10A2 | solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SSTR4 | somatostatin receptor 4 |
| TBKBP1 | TBK1 binding protein 1 |
| TEX40 | testis expressed 40 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TMEM2 | transmembrane protein 2 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TSPAN4 | tetraspanin 4 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| TUBA4B | tubulin, alpha 4b |
| WDR55 | WD repeat domain 55 |
| WNT2 | wingless-type MMTV integration site family member 2 |
| ZBTB1 | zinc finger and BTB domain containing 1 |
| ZNF205 | zinc finger protein 205 |
| ZNF280A | zinc finger protein 280A |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARG1 | arginase 1 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ARRB1 | arrestin, beta 1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC57 | coiled-coil domain containing 57 |
| CCDC85C | coiled-coil domain containing 85C |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CFAP44 | cilia and flagella associated protein 44 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CISH | cytokine inducible SH2-containing protein |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CNTLN | centlein, centrosomal protein |
| CRYGC | crystallin, gamma C |
| CTSV | cathepsin V |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ELMO3 | engulfment and cell motility 3 |
| ERCC2 | excision repair cross-complementation group 2 |
| FOXD1 | forkhead box D1 |
| FOXN2 | forkhead box N2 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GCH1 | GTP cyclohydrolase 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR75 | G protein-coupled receptor 75 |
| GRPR | gastrin-releasing peptide receptor |
| HDAC7 | histone deacetylase 7 |
| HIST1H2AI | histone cluster 1, H2ai |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| JUP | junction plakoglobin |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIF17 | kinesin family member 17 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LTC4S | leukotriene C4 synthase |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MEGF8 | multiple EGF-like-domains 8 |
| MTMR12 | myotubularin related protein 12 |
| MVP | major vault protein |
| MYH15 | myosin, heavy chain 15 |
| NAG18 | NAG18 mRNA |
| NEUROD4 | neuronal differentiation 4 |
| NME8 | NME/NM23 family member 8 |
| NNAT | neuronatin |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PADI2 | peptidyl arginine deiminase, type II |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE12 | phosphodiesterase 12 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDGFD | platelet derived growth factor D |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PLD3 | phospholipase D family, member 3 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| QPRT | quinolinate phosphoribosyltransferase |
| RAB13 | RAB13, member RAS oncogene family |
| RAB5B | RAB5B, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RANBP17 | RAN binding protein 17 |
| RCAN3 | RCAN family member 3 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF141 | ring finger protein 141 |
| S100A9 | S100 calcium binding protein A9 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SIK1 | salt-inducible kinase 1 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TERT | telomerase reverse transcriptase |
| TGM5 | transglutaminase 5 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM120B | transmembrane protein 120B |
| TMEM14A | transmembrane protein 14A |
| TPCN1 | two pore segment channel 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| USP6NL | USP6 N-terminal like |
| VASH2 | vasohibin 2 |
| VNN2 | vanin 2 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF219 | zinc finger protein 219 |
| ZNF574 | zinc finger protein 574 |
| ZNF667 | zinc finger protein 667 |
| ZNF76 | zinc finger protein 76 |
| ZNF787 | zinc finger protein 787 |
