| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the ebselen-3458 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACVR1B | activin A receptor, type IB |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| CBR3 | carbonyl reductase 3 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CD82 | CD82 molecule |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHKB | choline kinase beta |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DLX2 | distal-less homeobox 2 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP1 | dual specificity phosphatase 1 |
| EDNRB | endothelin receptor type B |
| EGF | epidermal growth factor |
| EGR1 | early growth response 1 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FAM174B | family with sequence similarity 174, member B |
| FAM46C | family with sequence similarity 46, member C |
| FECH | ferrochelatase |
| FGF2 | fibroblast growth factor 2 (basic) |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOSL1 | FOS-like antigen 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GMPR | guanosine monophosphate reductase |
| GPX2 | glutathione peroxidase 2 |
| GSTM4 | glutathione S-transferase mu 4 |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HFE | hemochromatosis |
| HIST1H1E | histone cluster 1, H1e |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL5RA | interleukin 5 receptor, alpha |
| IRS2 | insulin receptor substrate 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLK7 | kallikrein-related peptidase 7 |
| LEPR | leptin receptor |
| LOC399491 | |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| MVB12B | multivesicular body subunit 12B |
| MYF5 | myogenic factor 5 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| ONECUT2 | one cut homeobox 2 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PHF20 | PHD finger protein 20 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLAT | plasminogen activator, tissue |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRSS22 | protease, serine, 22 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RECQL5 | RecQ protein-like 5 |
| REEP1 | receptor accessory protein 1 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SQSTM1 | sequestosome 1 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TRIM16 | tripartite motif containing 16 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TXNRD1 | thioredoxin reductase 1 |
| UPP1 | uridine phosphorylase 1 |
| YIPF2 | Yip1 domain family, member 2 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF778 | zinc finger protein 778 |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| AEN | apoptosis enhancing nuclease |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ASL | argininosuccinate lyase |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BEX4 | brain expressed, X-linked 4 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CASZ1 | castor zinc finger 1 |
| CCDC47 | coiled-coil domain containing 47 |
| CDK20 | cyclin-dependent kinase 20 |
| CDK3 | cyclin-dependent kinase 3 |
| CEP72 | centrosomal protein 72kDa |
| CFD | complement factor D (adipsin) |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CORO2A | coronin, actin binding protein, 2A |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CST6 | cystatin E/M |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| ELMO3 | engulfment and cell motility 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FAM169A | family with sequence similarity 169, member A |
| FANCC | Fanconi anemia, complementation group C |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FLT4 | fms-related tyrosine kinase 4 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GHR | growth hormone receptor |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GRAMD4 | GRAM domain containing 4 |
| HDAC4 | histone deacetylase 4 |
| HIST1H2AM | histone cluster 1, H2am |
| HMG20A | high mobility group 20A |
| HMHA1 | histocompatibility (minor) HA-1 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IMPACT | impact RWD domain protein |
| IPO8 | importin 8 |
| KIAA0125 | KIAA0125 |
| KIF13B | kinesin family member 13B |
| KITLG | KIT ligand |
| KLHL26 | kelch-like family member 26 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MYL5 | myosin, light chain 5, regulatory |
| NCSTN | nicastrin |
| NIPAL2 | NIPA-like domain containing 2 |
| NMU | neuromedin U |
| NPY1R | neuropeptide Y receptor Y1 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OTUD3 | OTU deubiquitinase 3 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PGM1 | phosphoglucomutase 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PP14571 | uncharacterized LOC100130449 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKCD | protein kinase C, delta |
| PRR15L | proline rich 15-like |
| PSKH1 | protein serine kinase H1 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RSF1 | remodeling and spacing factor 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SIRT2 | sirtuin 2 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SP1 | Sp1 transcription factor |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TARP | TCR gamma alternate reading frame protein |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TSPAN14 | tetraspanin 14 |
| TWF2 | twinfilin actin binding protein 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| XYLT2 | xylosyltransferase II |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF205 | zinc finger protein 205 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
