eclampsia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A pre-eclampsia characterized by the presence of seizures. (Human Disease Ontology, DOID_13593)
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Genes

112 genes co-occuring with the disease eclampsia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PCDHB7 protocadherin beta 7 1.4057
TMEM207 transmembrane protein 207 1.23082
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.20483
MGAM maltase-glucoamylase 1.19532
ENKUR enkurin, TRPC channel interacting protein 1.18755
SPIN4 spindlin family, member 4 1.15368
APEH acylaminoacyl-peptide hydrolase 1.14857
EDF1 endothelial differentiation-related factor 1 1.13628
F2 coagulation factor II (thrombin) 1.06732
PGF placental growth factor 1.01174
F5 coagulation factor V (proaccelerin, labile factor) 1.00541
DBNL drebrin-like 0.900746
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.891308
KAT8 K(lysine) acetyltransferase 8 0.820847
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.768393
ALB albumin 0.756156
FLT1 fms-related tyrosine kinase 1 0.737865
THBD thrombomodulin 0.737054
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.737054
F3 coagulation factor III (thromboplastin, tissue factor) 0.732596
AQP11 aquaporin 11 0.714811
CDK11A cyclin-dependent kinase 11A 0.674315
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.660008
PROS1 protein S (alpha) 0.644981
BEX1 brain expressed, X-linked 1 0.641433
BEX2 brain expressed X-linked 2 0.640645
TFPI2 tissue factor pathway inhibitor 2 0.617486
NEGR1 neuronal growth regulator 1 0.60147
ARSI arylsulfatase family, member I 0.592506
DACT3 dishevelled-binding antagonist of beta-catenin 3 0.589779
AQP4 aquaporin 4 0.586276
KLHL21 kelch-like family member 21 0.574994
HPD 4-hydroxyphenylpyruvate dioxygenase 0.554015
TTC34 tetratricopeptide repeat domain 34 0.539667
EDN1 endothelin 1 0.514186
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.513417
EXOSC4 exosome component 4 0.505739
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.492359
ACE angiotensin I converting enzyme 0.489691
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.489311
GRB2 growth factor receptor-bound protein 2 0.48893
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.488549
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.487788
CCDC27 coiled-coil domain containing 27 0.483224
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.479047
DCTD dCMP deaminase 0.459751
SAMD11 sterile alpha motif domain containing 11 0.452585
FERMT1 fermitin family member 1 0.446935
LEPR leptin receptor 0.437906
SHD Src homology 2 domain containing transforming protein D 0.437154
AQP7 aquaporin 7 0.436778
LGALS13 lectin, galactoside-binding, soluble, 13 0.430768
AQP8 aquaporin 8 0.430768
POU3F4 POU class 3 homeobox 4 0.424014
LIG3 ligase III, DNA, ATP-dependent 0.412031
PER1 period circadian clock 1 0.408292
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.398216
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.397471
CUTA cutA divalent cation tolerance homolog (E. coli) 0.395235
FN1 fibronectin 1 0.395235
PLG plasminogen 0.392257
ANG angiogenin, ribonuclease, RNase A family, 5 0.387794
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.363716
CSH2 chorionic somatomammotropin hormone 2 0.344207
APOH apolipoprotein H (beta-2-glycoprotein I) 0.338341
POSTN periostin, osteoblast specific factor 0.329565
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.323365
PRDM2 PR domain containing 2, with ZNF domain 0.321181
RGS2 regulator of G-protein signaling 2 0.321181
REN renin 0.313189
ACSL1 acyl-CoA synthetase long-chain family member 1 0.312102
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.310652
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.304864
CAT catalase 0.303059
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.298371
PLAT plasminogen activator, tissue 0.289386
BBS1 Bardet-Biedl syndrome 1 0.281153
HP haptoglobin 0.280439
POMC proopiomelanocortin 0.279011
CLDN16 claudin 16 0.278654
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.277227
HPR haptoglobin-related protein 0.274732
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.274732
ACOT7 acyl-CoA thioesterase 7 0.274021
ASPH aspartate beta-hydroxylase 0.25207
FGR FGR proto-oncogene, Src family tyrosine kinase 0.249608
LEP leptin 0.241895
ADAM12 ADAM metallopeptidase domain 12 0.23492
GPX5 glutathione peroxidase 5 0.23353
GPX4 glutathione peroxidase 4 0.230755
AGTR1 angiotensin II receptor, type 1 0.221793
GPX1 glutathione peroxidase 1 0.216672
NOS3 nitric oxide synthase 3 (endothelial cell) 0.209918
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.207912
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.20229
CPN1 carboxypeptidase N, polypeptide 1 0.200656
AQP5 aquaporin 5 0.200006
MMP8 matrix metallopeptidase 8 0.196459
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.189551
F8 coagulation factor VIII, procoagulant component 0.188632
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.187415
RER1 retention in endoplasmic reticulum sorting receptor 1 0.18472
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.175679
IL31RA interleukin 31 receptor A 0.174881
AQP3 aquaporin 3 (Gill blood group) 0.173571
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.170544
POU2F3 POU class 2 homeobox 3 0.168381
SOD2 superoxide dismutase 2, mitochondrial 0.168148
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.165874
CDKN2A cyclin-dependent kinase inhibitor 2A 0.161912
INS insulin 0.158778
UTS2 urotensin 2 0.157602