econazole-6008 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the econazole-6008 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANG angiogenin, ribonuclease, RNase A family, 5
ARNT aryl hydrocarbon receptor nuclear translocator
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATF3 activating transcription factor 3
ATXN2L ataxin 2-like
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL2A1 BCL2-related protein A1
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
C8ORF44 chromosome 8 open reading frame 44
CA1 carbonic anhydrase I
CD3D CD3d molecule, delta (CD3-TCR complex)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CES3 carboxylesterase 3
CGA glycoprotein hormones, alpha polypeptide
COL14A1 collagen, type XIV, alpha 1
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DAPK1 death-associated protein kinase 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DIEXF digestive organ expansion factor homolog (zebrafish)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGR1 early growth response 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELOVL5 ELOVL fatty acid elongase 5
FADS3 fatty acid desaturase 3
FBXO40 F-box protein 40
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FYN FYN proto-oncogene, Src family tyrosine kinase
GAS7 growth arrest-specific 7
GRK5 G protein-coupled receptor kinase 5
GYPB glycophorin B (MNS blood group)
HFE hemochromatosis
HIST1H3B histone cluster 1, H3b
IL4 interleukin 4
INTS1 integrator complex subunit 1
IRF1 interferon regulatory factor 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JUN jun proto-oncogene
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDM4C lysine (K)-specific demethylase 4C
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLF2 Kruppel-like factor 2
KLHL24 kelch-like family member 24
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MEF2D myocyte enhancer factor 2D
MYLK myosin light chain kinase
MYO9B myosin IXB
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NFE2L3 nuclear factor, erythroid 2-like 3
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUP50 nucleoporin 50kDa
NUPR1 nuclear protein, transcriptional regulator, 1
OASL 2'-5'-oligoadenylate synthetase-like
PAX9 paired box 9
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POPDC3 popeye domain containing 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSG6 pregnancy specific beta-1-glycoprotein 6
PTGES prostaglandin E synthase
PVRL3 poliovirus receptor-related 3
RHBDD3 rhomboid domain containing 3
RND1 Rho family GTPase 1
S100A9 S100 calcium binding protein A9
SBNO1 strawberry notch homolog 1 (Drosophila)
SEC24A SEC24 family member A
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFTPB surfactant protein B
SIRT4 sirtuin 4
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SUGP1 SURP and G patch domain containing 1
TCEAL2 transcription elongation factor A (SII)-like 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNK2 tyrosine kinase, non-receptor, 2
TNNT2 troponin T type 2 (cardiac)
TPP1 tripeptidyl peptidase I
TRIL TLR4 interactor with leucine-rich repeats
TRIM3 tripartite motif containing 3
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
VLDLR very low density lipoprotein receptor
ZFP64 ZFP64 zinc finger protein
ZNF391 zinc finger protein 391
ZNF419 zinc finger protein 419
ZNF506 zinc finger protein 506
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACOX3 acyl-CoA oxidase 3, pristanoyl
ACSL4 acyl-CoA synthetase long-chain family member 4
ALS2CL ALS2 C-terminal like
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATAD5 ATPase family, AAA domain containing 5
BTF3P12 basic transcription factor 3 pseudogene 12
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C5AR2 complement component 5a receptor 2
CAMTA1 calmodulin binding transcription activator 1
CBR4 carbonyl reductase 4
CCDC85C coiled-coil domain containing 85C
CD82 CD82 molecule
CFAP44 cilia and flagella associated protein 44
CHML choroideremia-like (Rab escort protein 2)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRIP1 cysteine-rich protein 1 (intestinal)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DSE dermatan sulfate epimerase
EIF5A2 eukaryotic translation initiation factor 5A2
FBRS fibrosin
FGL1 fibrinogen-like 1
FKBP10 FK506 binding protein 10, 65 kDa
FKBP5 FK506 binding protein 5
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GPR19 G protein-coupled receptor 19
HOXA4 homeobox A4
HOXD11 homeobox D11
IFI6 interferon, alpha-inducible protein 6
IFT140 intraflagellar transport 140
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INCENP inner centromere protein antigens 135/155kDa
ITPKB inositol-trisphosphate 3-kinase B
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA1456 KIAA1456
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MED15 mediator complex subunit 15
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MRPL44 mitochondrial ribosomal protein L44
MTMR12 myotubularin related protein 12
MYO1E myosin IE
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEUROD4 neuronal differentiation 4
NHLRC2 NHL repeat containing 2
NUBP2 nucleotide binding protein 2
ONECUT2 one cut homeobox 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAQR6 progestin and adipoQ receptor family member VI
PDE12 phosphodiesterase 12
PITX2 paired-like homeodomain 2
PLA2G10 phospholipase A2, group X
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLH polymerase (DNA directed), eta
POMT2 protein-O-mannosyltransferase 2
PROCR protein C receptor, endothelial
PROS1 protein S (alpha)
PTPRS protein tyrosine phosphatase, receptor type, S
RAB30 RAB30, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNF43 ring finger protein 43
SAMD9 sterile alpha motif domain containing 9
SDC3 syndecan 3
SERGEF secretion regulating guanine nucleotide exchange factor
SKA1 spindle and kinetochore associated complex subunit 1
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SPRYD7 SPRY domain containing 7
SSBP3 single stranded DNA binding protein 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCTN2 tectonic family member 2
TET3 tet methylcytosine dioxygenase 3
THBS3 thrombospondin 3
TLR5 toll-like receptor 5
TMEM120B transmembrane protein 120B
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TMEM254 transmembrane protein 254
TOM1 target of myb1 (chicken)
USP27X ubiquitin specific peptidase 27, X-linked
VASH2 vasohibin 2
VAX2 ventral anterior homeobox 2
WWC2 WW and C2 domain containing 2
XYLT2 xylosyltransferase II
ZNF136 zinc finger protein 136
ZNF304 zinc finger protein 304
ZNF324 zinc finger protein 324
ZNF35 zinc finger protein 35
ZNF365 zinc finger protein 365
ZNF480 zinc finger protein 480
ZNF606 zinc finger protein 606
ZNF669 zinc finger protein 669
ZNF747 zinc finger protein 747