econazole-7427 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the econazole-7427 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
ARHGAP26 Rho GTPase activating protein 26
ATF3 activating transcription factor 3
ATF7IP activating transcription factor 7 interacting protein
ATN1 atrophin 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BTN2A2 butyrophilin, subfamily 2, member A2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD6 CD6 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIDEC cell death-inducing DFFA-like effector c
CLDN17 claudin 17
CTAGE9 CTAGE family, member 9
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
EIF5 eukaryotic translation initiation factor 5
ELL2 elongation factor, RNA polymerase II, 2
FAM63A family with sequence similarity 63, member A
FANCA Fanconi anemia, complementation group A
FBXO38 F-box protein 38
FBXO9 F-box protein 9
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FKBP14 FK506 binding protein 14, 22 kDa
FLOT1 flotillin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FSTL3 follistatin-like 3 (secreted glycoprotein)
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
GM2A GM2 ganglioside activator
GOSR2 golgi SNAP receptor complex member 2
GP1BB glycoprotein Ib (platelet), beta polypeptide
GRB10 growth factor receptor-bound protein 10
GRIK5 glutamate receptor, ionotropic, kainate 5
GYPB glycophorin B (MNS blood group)
HBS1L HBS1-like translational GTPase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HFE hemochromatosis
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL4R interleukin 4 receptor
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KIAA1109 KIAA1109
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
KLHL26 kelch-like family member 26
LOC730101 uncharacterized LOC730101
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MFAP3L microfibrillar-associated protein 3-like
MPDZ multiple PDZ domain protein
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MYT1 myelin transcription factor 1
NDE1 nudE neurodevelopment protein 1
NF2 neurofibromin 2 (merlin)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OASL 2'-5'-oligoadenylate synthetase-like
PDE12 phosphodiesterase 12
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIAS4 protein inhibitor of activated STAT, 4
PLK4 polo-like kinase 4
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POFUT1 protein O-fucosyltransferase 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RANBP3 RAN binding protein 3
RARG retinoic acid receptor, gamma
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOS2 son of sevenless homolog 2 (Drosophila)
SRCAP Snf2-related CREBBP activator protein
SYNGR3 synaptogyrin 3
SYT17 synaptotagmin XVII
TICAM1 toll-like receptor adaptor molecule 1
TMPRSS2 transmembrane protease, serine 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNPO3 transportin 3
TRIM2 tripartite motif containing 2
TUSC3 tumor suppressor candidate 3
ZC3H12A zinc finger CCCH-type containing 12A
ZNF710 zinc finger protein 710
ZNF767P zinc finger family member 767, pseudogene

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APH1A APH1A gamma secretase subunit
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BACE1 beta-site APP-cleaving enzyme 1
BAX BCL2-associated X protein
C14ORF132 chromosome 14 open reading frame 132
C19ORF40 chromosome 19 open reading frame 40
C9ORF78 chromosome 9 open reading frame 78
CAMKMT calmodulin-lysine N-methyltransferase
CBX8 chromobox homolog 8
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP131 centrosomal protein 131kDa
CEP170B centrosomal protein 170B
CLSPN claspin
ENDOD1 endonuclease domain containing 1
EXTL2 exostosin-like glycosyltransferase 2
FAM53B family with sequence similarity 53, member B
FZD4 frizzled class receptor 4
GAB2 GRB2-associated binding protein 2
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GDAP2 ganglioside induced differentiation associated protein 2
GHR growth hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
GLCE glucuronic acid epimerase
GLI3 GLI family zinc finger 3
GPR19 G protein-coupled receptor 19
GRB7 growth factor receptor-bound protein 7
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H2AJ histone cluster 1, H2aj
HOXC10 homeobox C10
IMPACT impact RWD domain protein
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIFC1 kinesin family member C1
KLHL36 kelch-like family member 36
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRC37A2 leucine rich repeat containing 37, member A2
LRRC42 leucine rich repeat containing 42
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAGEH1 melanoma antigen family H1
MECR mitochondrial trans-2-enoyl-CoA reductase
MMP9 matrix metallopeptidase 9
MTHFSD methenyltetrahydrofolate synthetase domain containing
MUM1 melanoma associated antigen (mutated) 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NUP62CL nucleoporin 62kDa C-terminal like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAQR3 progestin and adipoQ receptor family member III
PECR peroxisomal trans-2-enoyl-CoA reductase
PFDN6 prefoldin subunit 6
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PMP22 peripheral myelin protein 22
PNPLA6 patatin-like phospholipase domain containing 6
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PRKX protein kinase, X-linked
PRR14L proline rich 14-like
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RECQL4 RecQ protein-like 4
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SLC12A9 solute carrier family 12, member 9
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SNIP1 Smad nuclear interacting protein 1
SNORA21 small nucleolar RNA, H/ACA box 21
SOX12 SRY (sex determining region Y)-box 12
SPATA2L spermatogenesis associated 2-like
SPRYD7 SPRY domain containing 7
STARD13 StAR-related lipid transfer (START) domain containing 13
TM7SF3 transmembrane 7 superfamily member 3
TP53BP1 tumor protein p53 binding protein 1
TPCN1 two pore segment channel 1
TRABD TraB domain containing
TSPAN14 tetraspanin 14
TTC4 tetratricopeptide repeat domain 4
TUBA3C tubulin, alpha 3c
UBE2L6 ubiquitin-conjugating enzyme E2L 6
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBED1 zinc finger, BED-type containing 1
ZBED8 zinc finger, BED-type containing 8
ZNF14 zinc finger protein 14
ZNF226 zinc finger protein 226
ZNF250 zinc finger protein 250
ZNF286A zinc finger protein 286A
ZNF365 zinc finger protein 365
ZNF552 zinc finger protein 552
ZNF629 zinc finger protein 629