effector Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

749 genes co-occuring with the biological term effector in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACAN aggrecan
ACKR2 atypical chemokine receptor 2
ADA adenosine deaminase
ADAM17 ADAM metallopeptidase domain 17
ADCY7 adenylate cyclase 7
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
ADRA1D adrenoceptor alpha 1D
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGER advanced glycosylation end product-specific receptor
AGO2 argonaute RISC catalytic component 2
AIRE autoimmune regulator
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANGPT2 angiopoietin 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOB apolipoprotein B
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APP amyloid beta (A4) precursor protein
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AR androgen receptor
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARF6 ADP-ribosylation factor 6
ARHGAP15 Rho GTPase activating protein 15
ARHGAP26 Rho GTPase activating protein 26
ARHGAP35 Rho GTPase activating protein 35
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARL2 ADP-ribosylation factor-like 2
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ASCL1 achaete-scute family bHLH transcription factor 1
ATM ATM serine/threonine kinase
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
AXL AXL receptor tyrosine kinase
AZU1 azurocidin 1
B3GAT1 beta-1,3-glucuronyltransferase 1
BAD BCL2-associated agonist of cell death
BAIAP2 BAI1-associated protein 2
BAK1 BCL2-antagonist/killer 1
BANF1 barrier to autointegration factor 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L12 BCL2-like 12 (proline rich)
BCL2L2 BCL2-like 2
BDNF brain-derived neurotrophic factor
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
BMX BMX non-receptor tyrosine kinase
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
C3 complement component 3
C5 complement component 5
CADM1 cell adhesion molecule 1
CALCOCO2 calcium binding and coiled-coil domain 2
CALR calreticulin
CALY calcyon neuron-specific vesicular protein
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAMP cathelicidin antimicrobial peptide
CARD11 caspase recruitment domain family, member 11
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCL16 chemokine (C-C motif) ligand 16
CCL2 chemokine (C-C motif) ligand 2
CCL26 chemokine (C-C motif) ligand 26
CCL5 chemokine (C-C motif) ligand 5
CCNA2 cyclin A2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCR8 chemokine (C-C motif) receptor 8
CD160 CD160 molecule
CD1D CD1d molecule
CD2 CD2 molecule
CD226 CD226 molecule
CD24 CD24 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD27 CD27 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD300C CD300c molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD69 CD69 molecule
CD70 CD70 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CD96 CD96 molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK11A cyclin-dependent kinase 11A
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDX2 caudal type homeobox 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGA glycoprotein hormones, alpha polypeptide
CGB5 chorionic gonadotropin, beta polypeptide 5
CHD1L chromodomain helicase DNA binding protein 1-like
CHEK2 checkpoint kinase 2
CHIA chitinase, acidic
CIDEA cell death-inducing DFFA-like effector a
CIDEC cell death-inducing DFFA-like effector c
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLEC2B C-type lectin domain family 2, member B
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNOT1 CCR4-NOT transcription complex, subunit 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COPS5 COP9 signalosome subunit 5
CORO1A coronin, actin binding protein, 1A
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CRH corticotropin releasing hormone
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CRYAB crystallin, alpha B
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSD cathepsin D
CTSL cathepsin L
CTSW cathepsin W
CTTN cortactin
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR6 chemokine (C-X-C motif) receptor 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAAM1 dishevelled associated activator of morphogenesis 1
DCLRE1C DNA cross-link repair 1C
DCN decorin
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEK DEK proto-oncogene
DENND5A DENN/MADD domain containing 5A
DGKZ diacylglycerol kinase, zeta
DIABLO diablo, IAP-binding mitochondrial protein
DICER1 dicer 1, ribonuclease type III
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DNM1 dynamin 1
DNM1L dynamin 1-like
DNM2 dynamin 2
DOCK1 dedicator of cytokinesis 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPP4 dipeptidyl-peptidase 4
DRD3 dopamine receptor D3
DTNA dystrobrevin, alpha
DUSP1 dual specificity phosphatase 1
E4F1 E4F transcription factor 1
EFNB2 ephrin-B2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EHD1 EH-domain containing 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4B eukaryotic translation initiation factor 4B
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ELAVL1 ELAV like RNA binding protein 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELMOD1 ELMO/CED-12 domain containing 1
ELMOD2 ELMO/CED-12 domain containing 2
ELMOD3 ELMO/CED-12 domain containing 3
EMD emerin
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EOMES eomesodermin
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV5 ets variant 5
EXOC2 exocyst complex component 2
EXOC6 exocyst complex component 6
EXOC6B exocyst complex component 6B
EXOC8 exocyst complex component 8
EXPH5 exophilin 5
EZR ezrin
F11R F11 receptor
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADD Fas (TNFRSF6)-associated via death domain
FAM109A family with sequence similarity 109, member A
FAM109B family with sequence similarity 109, member B
FANCD2 Fanconi anemia, complementation group D2
FANCM Fanconi anemia, complementation group M
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXO22 F-box protein 22
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCAR Fc fragment of IgA receptor
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCRL6 Fc receptor-like 6
FDPS farnesyl diphosphate synthase
FES FES proto-oncogene, tyrosine kinase
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FILIP1L filamin A interacting protein 1-like
FKBP8 FK506 binding protein 8, 38kDa
FLT1 fms-related tyrosine kinase 1
FMNL2 formin-like 2
FOXA2 forkhead box A2
FOXO1 forkhead box O1
FOXO4 forkhead box O4
FOXP3 forkhead box P3
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FXN frataxin
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD9 frizzled class receptor 9
GABARAPL2 GABA(A) receptor-associated protein-like 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GLI1 GLI family zinc finger 1
GLP2R glucagon-like peptide 2 receptor
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GNLY granulysin
GORASP2 golgi reassembly stacking protein 2, 55kDa
GP6 glycoprotein VI (platelet)
GPC3 glypican 3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPSM1 G-protein signaling modulator 1
GRK6 G protein-coupled receptor kinase 6
GSK3B glycogen synthase kinase 3 beta
GUCA1A guanylate cyclase activator 1A (retina)
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HBA1 hemoglobin, alpha 1
HCK HCK proto-oncogene, Src family tyrosine kinase
HDAC3 histone deacetylase 3
HDAC9 histone deacetylase 9
HES5 hes family bHLH transcription factor 5
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK2 homeodomain interacting protein kinase 2
HLA-E major histocompatibility complex, class I, E
HLX H2.0-like homeobox
HMGN2 high mobility group nucleosomal binding domain 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNRNPA1P10 heterogeneous nuclear ribonucleoprotein A1 pseudogene 10
HNRNPK heterogeneous nuclear ribonucleoprotein K
HOXA1 homeobox A1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPS1 Hermansky-Pudlak syndrome 1
HPS4 Hermansky-Pudlak syndrome 4
HRAS Harvey rat sarcoma viral oncogene homolog
HRH4 histamine receptor H4
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPB1 heat shock 27kDa protein 1
HTRA3 HtrA serine peptidase 3
IAPP islet amyloid polypeptide
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IDO2 indoleamine 2,3-dioxygenase 2
IER3 immediate early response 3
IFI16 interferon, gamma-inducible protein 16
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IFN1@ interferon, type 1, cluster
IFNA1 interferon, alpha 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGF2R insulin-like growth factor 2 receptor
IGFBP6 insulin-like growth factor binding protein 6
IGHE immunoglobulin heavy constant epsilon
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL2 interleukin 2
IL20 interleukin 20
IL21 interleukin 21
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL25 interleukin 25
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL31 interleukin 31
IL34 interleukin 34
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
IL7 interleukin 7
IL7R interleukin 7 receptor
IL9 interleukin 9
ILK integrin-linked kinase
INHBA inhibin, beta A
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
ITGA1 integrin, alpha 1
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB4 integrin, beta 4
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JAKMIP1 janus kinase and microtubule interacting protein 1
JUN jun proto-oncogene
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNK3 potassium channel, two pore domain subfamily K, member 3
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNK9 potassium channel, two pore domain subfamily K, member 9
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM1A lysine (K)-specific demethylase 1A
KIAA0226 KIAA0226
KIF16B kinesin family member 16B
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRIT1 KRIT1, ankyrin repeat containing
LAG3 lymphocyte-activation gene 3
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMP1 lysosomal-associated membrane protein 1
LAT linker for activation of T cells
LAX1 lymphocyte transmembrane adaptor 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS2 lectin, galactoside-binding, soluble, 2
LGALS9 lectin, galactoside-binding, soluble, 9
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LTB4R leukotriene B4 receptor
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
MAML1 mastermind-like 1 (Drosophila)
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MAVS mitochondrial antiviral signaling protein
MBL2 mannose-binding lectin (protein C) 2, soluble
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MICA MHC class I polypeptide-related sequence A
MICALL1 MICAL-like 1
MICB MHC class I polypeptide-related sequence B
MIR133A1 microRNA 133a-1
MIR133B microRNA 133b
MIR135B microRNA 135b
MIR155 microRNA 155
MIR17 microRNA 17
MIR17HG miR-17-92 cluster host gene
MIR200B microRNA 200b
MIR21 microRNA 21
MIR375 microRNA 375
MIR520C microRNA 520c
MIRLET7B microRNA let-7b
MIRLET7G microRNA let-7g
MISP mitotic spindle positioning
MLPH melanophilin
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MPL MPL proto-oncogene, thrombopoietin receptor
MSX2 msh homeobox 2
MTA1 metastasis associated 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYH9 myosin, heavy chain 9, non-muscle
MYL1 myosin, light chain 1, alkali; skeletal, fast
NANOG Nanog homeobox
NANOS1 nanos homolog 1 (Drosophila)
NBR1 neighbor of BRCA1 gene 1
NCK1 NCK adaptor protein 1
NCR1 natural cytotoxicity triggering receptor 1
NCR2 natural cytotoxicity triggering receptor 2
NCR3 natural cytotoxicity triggering receptor 3
NDRG1 N-myc downstream regulated 1
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NEO1 neogenin 1
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOD1 nucleotide-binding oligomerization domain containing 1
NOTCH1 notch 1
NOTCH2 notch 2
NOX4 NADPH oxidase 4
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRP2 neuropilin 2
NTN1 netrin 1
OCRL oculocerebrorenal syndrome of Lowe
PA2G4 proliferation-associated 2G4, 38kDa
PACS2 phosphofurin acidic cluster sorting protein 2
PAEP progestagen-associated endometrial protein
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARD6A par-6 family cell polarity regulator alpha
PARK7 parkinson protein 7
PARP1 poly (ADP-ribose) polymerase 1
PARP14 poly (ADP-ribose) polymerase family, member 14
PAX8 paired box 8
PBK PDZ binding kinase
PCBP1 poly(rC) binding protein 1
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDE4B phosphodiesterase 4B, cAMP-specific
PDPN podoplanin
PEA15 phosphoprotein enriched in astrocytes 15
PEBP1 phosphatidylethanolamine binding protein 1
PERP PERP, TP53 apoptosis effector
PFN1 profilin 1
PHB prohibitin
PHGDH phosphoglycerate dehydrogenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PI3 peptidase inhibitor 3, skin-derived
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PITX2 paired-like homeodomain 2
PIWIL2 piwi-like RNA-mediated gene silencing 2
PKN1 protein kinase N1
PKP2 plakophilin 2
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAT plasminogen activator, tissue
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLG plasminogen
PLIN3 perilipin 3
PLSCR3 phospholipid scramblase 3
PLXNB1 plexin B1
PLXND1 plexin D1
PML promyelocytic leukemia
POMC proopiomelanocortin
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRF1 perforin 1 (pore forming protein)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRMT5 protein arginine methyltransferase 5
PROCR protein C receptor, endothelial
PSENEN presenilin enhancer gamma secretase subunit
PTEN phosphatase and tensin homolog
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTH1R parathyroid hormone 1 receptor
PTHLH parathyroid hormone-like hormone
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTRH2 peptidyl-tRNA hydrolase 2
PTX3 pentraxin 3, long
PVR poliovirus receptor
PXN paxillin
RAB11A RAB11A, member RAS oncogene family
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB14 RAB14, member RAS oncogene family
RAB15 RAB15, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB27A RAB27A, member RAS oncogene family
RAB2A RAB2A, member RAS oncogene family
RAB33B RAB33B, member RAS oncogene family
RAB34 RAB34, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RADIL Ras association and DIL domains
RALB v-ral simian leukemia viral oncogene homolog B
RALBP1 ralA binding protein 1
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAP2A RAP2A, member of RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASIP1 Ras interacting protein 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RASSF6 Ras association (RalGDS/AF-6) domain family member 6
RB1 retinoblastoma 1
RBSN rabenosyn, RAB effector
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RET ret proto-oncogene
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHEB Ras homolog enriched in brain
RHO rhodopsin
RHOA ras homolog family member A
RHOC ras homolog family member C
RHOD ras homolog family member D
RHOG ras homolog family member G
RHOJ ras homolog family member J
RICTOR RPTOR independent companion of MTOR, complex 2
RIF1 replication timing regulatory factor 1
RILP Rab interacting lysosomal protein
RND1 Rho family GTPase 1
RND3 Rho family GTPase 3
RNF2 ring finger protein 2
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPH3AL rabphilin 3A-like (without C2 domains)
RPS12 ribosomal protein S12
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPTOR regulatory associated protein of MTOR, complex 1
RSAD2 radical S-adenosyl methionine domain containing 2
RYK receptor-like tyrosine kinase
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
SATB1 SATB homeobox 1
SAV1 salvador family WW domain containing protein 1
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SCO2 SCO2 cytochrome c oxidase assembly protein
SCYL1 SCY1-like 1 (S. cerevisiae)
SEC14L1 SEC14-like 1 (S. cerevisiae)
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SETD8 SET domain containing (lysine methyltransferase) 8
SGK223 homolog of rat pragma of Rnd2
SH3BP1 SH3-domain binding protein 1
SHH sonic hedgehog
SIGMAR1 sigma non-opioid intracellular receptor 1
SIRT1 sirtuin 1
SIRT6 sirtuin 6
SKP1 S-phase kinase-associated protein 1
SLAMF7 SLAM family member 7
SLC25A27 solute carrier family 25, member 27
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPHK1 sphingosine kinase 1
SPP1 secreted phosphoprotein 1
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK3 serine/threonine kinase 3
STMN2 stathmin 2
STX11 syntaxin 11
STXBP1 syntaxin binding protein 1
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
SUMO1 small ubiquitin-like modifier 1
SYBU syntabulin (syntaxin-interacting)
SYK spleen tyrosine kinase
SYTL4 synaptotagmin-like 4
SYTL5 synaptotagmin-like 5
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TBC1D4 TBC1 domain family, member 4
TBK1 TANK-binding kinase 1
TBX21 T-box 21
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDRD3 tudor domain containing 3
TEK TEK tyrosine kinase, endothelial
TERF2 telomeric repeat binding factor 2
TERF2IP telomeric repeat binding factor 2, interacting protein
TERT telomerase reverse transcriptase
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TFF3 trefoil factor 3 (intestinal)
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TIGIT T cell immunoreceptor with Ig and ITIM domains
TLR2 toll-like receptor 2
TLR5 toll-like receptor 5
TMC8 transmembrane channel-like 8
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNIK TRAF2 and NCK interacting kinase
TNRC6A trinucleotide repeat containing 6A
TNRC6C trinucleotide repeat containing 6C
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
TRB T cell receptor beta locus
TRD T cell receptor delta locus
TRG T cell receptor gamma locus
TRIM22 tripartite motif containing 22
TRIM28 tripartite motif containing 28
TRIM33 tripartite motif containing 33
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSLP thymic stromal lymphopoietin
TWIST1 twist family bHLH transcription factor 1
TXN thioredoxin
TXNL1 thioredoxin-like 1
UBASH3B ubiquitin associated and SH3 domain containing B
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
UNC13B unc-13 homolog B (C. elegans)
UNC13D unc-13 homolog D (C. elegans)
UNC5B unc-5 homolog B (C. elegans)
URGCP upregulator of cell proliferation
USP22 ubiquitin specific peptidase 22
USP6 ubiquitin specific peptidase 6
VANGL1 VANGL planar cell polarity protein 1
VAV1 vav 1 guanine nucleotide exchange factor
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
VPRBP Vpr (HIV-1) binding protein
VWCE von Willebrand factor C and EGF domains
VWF von Willebrand factor
WNT2B wingless-type MMTV integration site family, member 2B
WNT3A wingless-type MMTV integration site family, member 3A
WNT7A wingless-type MMTV integration site family, member 7A
WNT9B wingless-type MMTV integration site family, member 9B
WT1 Wilms tumor 1
WWTR1 WW domain containing transcription regulator 1
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPO1 exportin 1
YAP1 Yes-associated protein 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB16 zinc finger and BTB domain containing 16
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF260 zinc finger protein 260
ZNF268 zinc finger protein 268
ZNF750 zinc finger protein 750