effector Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

405 proteins co-occuring with the biological term effector in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ADAM17 ADAM metallopeptidase domain 17
ADD1 adducin 1 (alpha)
ADRA2A adrenoceptor alpha 2A
ADRBK1 adrenergic, beta, receptor kinase 1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGO2 argonaute RISC catalytic component 2
AGTR1 angiotensin II receptor, type 1
AICDA activation-induced cytidine deaminase
AJUBA ajuba LIM protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKTIP AKT interacting protein
ALB albumin
ALK anaplastic lymphoma receptor tyrosine kinase
ALYREF Aly/REF export factor
ANKRD17 ankyrin repeat domain 17
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGAP15 Rho GTPase activating protein 15
ARHGAP35 Rho GTPase activating protein 35
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF2 activating transcription factor 2
ATG5 autophagy related 5
ATM ATM serine/threonine kinase
ATRIP ATR interacting protein
AVEN apoptosis, caspase activation inhibitor
AXL AXL receptor tyrosine kinase
BAD BCL2-associated agonist of cell death
BAIAP2 BAI1-associated protein 2
BBC3 BCL2 binding component 3
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
BLNK B-cell linker
BMX BMX non-receptor tyrosine kinase
BPGM 2,3-bisphosphoglycerate mutase
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRSK1 BR serine/threonine kinase 1
BRSK2 BR serine/threonine kinase 2
BTK Bruton agammaglobulinemia tyrosine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALD1 caldesmon 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD22 CD22 molecule
CD247 CD247 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD79A CD79a molecule, immunoglobulin-associated alpha
CD84 CD84 molecule
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDK5 cyclin-dependent kinase 5
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFL1 cofilin 1 (non-muscle)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CLEC1B C-type lectin domain family 1, member B
CLTC clathrin, heavy chain (Hc)
COX2
COX5A cytochrome c oxidase subunit Va
COX5B cytochrome c oxidase subunit Vb
COX7C cytochrome c oxidase subunit VIIc
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CRHR1 corticotropin releasing hormone receptor 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRMP1 collapsin response mediator protein 1
CROCC ciliary rootlet coiled-coil, rootletin
CRYAB crystallin, alpha B
CSF1R colony stimulating factor 1 receptor
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CXCR4 chemokine (C-X-C motif) receptor 4
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK1 death-associated protein kinase 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCLRE1C DNA cross-link repair 1C
DCP1A decapping mRNA 1A
DCTN1 dynactin 1
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DIAPH1 diaphanous-related formin 1
DNM1L dynamin 1-like
DNM2 dynamin 2
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPYSL2 dihydropyrimidinase-like 2
DSTN destrin (actin depolymerizing factor)
DVL2 dishevelled segment polarity protein 2
E2F3 E2F transcription factor 3
EEA1 early endosome antigen 1
EFNB2 ephrin-B2
EGFR epidermal growth factor receptor
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELK1 ELK1, member of ETS oncogene family
EMD emerin
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERF Ets2 repressor factor
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV1 ets variant 1
EZR ezrin
FADD Fas (TNFRSF6)-associated via death domain
FCRL6 Fc receptor-like 6
FGF2 fibroblast growth factor 2 (basic)
FHIT fragile histidine triad
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FMR1 fragile X mental retardation 1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FXR1 fragile X mental retardation, autosomal homolog 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAB2 GRB2-associated binding protein 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GAP43 growth associated protein 43
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA4 GATA binding protein 4
GCH1 GTP cyclohydrolase 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJA1 gap junction protein, alpha 1, 43kDa
GLI1 GLI family zinc finger 1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
H2AFX H2A histone family, member X
HCLS1 hematopoietic cell-specific Lyn substrate 1
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HIST1H3A histone cluster 1, H3a
HSPB1 heat shock 27kDa protein 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IER3 immediate early response 3
IFI16 interferon, gamma-inducible protein 16
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL4R interleukin 4 receptor
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
IRF3 interferon regulatory factor 3
IRF5 interferon regulatory factor 5
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGB4 integrin, beta 4
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KALRN kalirin, RhoGEF kinase
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNK2 potassium channel, two pore domain subfamily K, member 2
KDR kinase insert domain receptor
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT8 keratin 8, type II
KSR1 kinase suppressor of ras 1
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
LHCGR luteinizing hormone/choriogonadotropin receptor
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
LPCAT1 lysophosphatidylcholine acyltransferase 1
LRRK2 leucine-rich repeat kinase 2
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MAPT microtubule-associated protein tau
MARCKS myristoylated alanine-rich protein kinase C substrate
MARK2 MAP/microtubule affinity-regulating kinase 2
MCM2 minichromosome maintenance complex component 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED1 mediator complex subunit 1
MEF2C myocyte enhancer factor 2C
MEF2D myocyte enhancer factor 2D
MET MET proto-oncogene, receptor tyrosine kinase
MSN moesin
MSX2 msh homeobox 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH9 myosin, heavy chain 9, non-muscle
MYL12B myosin, light chain 12B, regulatory
MYL9 myosin, light chain 9, regulatory
NBN nibrin
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NDRG1 N-myc downstream regulated 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NET1 neuroepithelial cell transforming 1
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFE2 nuclear factor, erythroid 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKX3-1 NK3 homeobox 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
PA2G4 proliferation-associated 2G4, 38kDa
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PANX2 pannexin 2
PARD3 par-3 family cell polarity regulator
PARVA parvin, alpha
PDC phosducin
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PDX1 pancreatic and duodenal homeobox 1
PDZD11 PDZ domain containing 11
PEA15 phosphoprotein enriched in astrocytes 15
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIKFYVE phosphoinositide kinase, FYVE finger containing
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PKLR pyruvate kinase, liver and RBC
PKM pyruvate kinase, muscle
PKN1 protein kinase N1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCG1 phospholipase C, gamma 1
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLK1 polo-like kinase 1
PLN phospholamban
PLSCR3 phospholipid scramblase 3
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRDX1 peroxiredoxin 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCQ protein kinase C, theta
PRKD1 protein kinase D1
PRLR prolactin receptor
PTEN phosphatase and tensin homolog
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
PTPRA protein tyrosine phosphatase, receptor type, A
PTPRE protein tyrosine phosphatase, receptor type, E
PTTG1 pituitary tumor-transforming 1
PXN paxillin
PYGM phosphorylase, glycogen, muscle
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB24 RAB24, member RAS oncogene family
RAB3IP RAB3A interacting protein
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAD9A RAD9 homolog A (S. pombe)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RAP1B RAP1B, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBSN rabenosyn, RAB effector
RDX radixin
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RGS14 regulator of G-protein signaling 14
RGS16 regulator of G-protein signaling 16
RHOA ras homolog family member A
RHOU ras homolog family member U
RIMS1 regulating synaptic membrane exocytosis 1
RIN1 Ras and Rab interactor 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPH3A rabphilin 3A
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPTOR regulatory associated protein of MTOR, complex 1
RRAS related RAS viral (r-ras) oncogene homolog
RRM2 ribonucleotide reductase M2
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RTKN rhotekin
RUFY1 RUN and FYVE domain containing 1
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
SATB1 SATB homeobox 1
SETMAR SET domain and mariner transposase fusion gene
SH2B3 SH2B adaptor protein 3
SH3GL2 SH3-domain GRB2-like 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMC1A structural maintenance of chromosomes 1A
SNAP25 synaptosomal-associated protein, 25kDa
SP1 Sp1 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRCIN1 SRC kinase signaling inhibitor 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK11 serine/threonine kinase 11
STK3 serine/threonine kinase 3
STK38 serine/threonine kinase 38
STK4 serine/threonine kinase 4
STMN1 stathmin 1
STMN2 stathmin 2
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SYK spleen tyrosine kinase
SYN1 synapsin I
SYN3 synapsin III
TBC1D4 TBC1 domain family, member 4
TBX21 T-box 21
TIAM1 T-cell lymphoma invasion and metastasis 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TIGIT T cell immunoreceptor with Ig and ITIM domains
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53
TRIM28 tripartite motif containing 28
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TWIST1 twist family bHLH transcription factor 1
USO1 USO1 vesicle transport factor
VASP vasodilator-stimulated phosphoprotein
VAV1 vav 1 guanine nucleotide exchange factor
VIM vimentin
WAS Wiskott-Aldrich syndrome
WASF1 WAS protein family, member 1
WASL Wiskott-Aldrich syndrome-like
WWOX WW domain containing oxidoreductase
XPO1 exportin 1
YAP1 Yes-associated protein 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZFP36 ZFP36 ring finger protein