efficiency Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

422 genes co-occuring with the biological term efficiency in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACY1 aminoacylase 1
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADARB1 adenosine deaminase, RNA-specific, B1
ADORA2A adenosine A2a receptor
ADRB2 adrenoceptor beta 2, surface
AK1 adenylate kinase 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALB albumin
ALYREF Aly/REF export factor
ANXA2 annexin A2
ANXA5 annexin A5
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOB apolipoprotein B
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARG1 arginase 1
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
AS3MT arsenite methyltransferase
ASCL1 achaete-scute family bHLH transcription factor 1
ASF1A anti-silencing function 1A histone chaperone
ASF1B anti-silencing function 1B histone chaperone
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATM ATM serine/threonine kinase
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
AVPR2 arginine vasopressin receptor 2
AXL AXL receptor tyrosine kinase
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BACE1 beta-site APP-cleaving enzyme 1
BCHE butyrylcholinesterase
BCL2L1 BCL2-like 1
BCO1 beta-carotene oxygenase 1
BDNF brain-derived neurotrophic factor
BID BH3 interacting domain death agonist
BIRC3 baculoviral IAP repeat containing 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BST2 bone marrow stromal cell antigen 2
C7ORF49 chromosome 7 open reading frame 49
CA2 carbonic anhydrase II
CANX calnexin
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAT catalase
CBS cystathionine-beta-synthase
CBX2 chromobox homolog 2
CBX5 chromobox homolog 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD209 CD209 molecule
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CD52 CD52 molecule
CD80 CD80 molecule
CDA cytidine deaminase
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CES3 carboxylesterase 3
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHAT choline O-acetyltransferase
CHIT1 chitinase 1 (chitotriosidase)
CHRM3 cholinergic receptor, muscarinic 3
CLCN4 chloride channel, voltage-sensitive 4
CLEC4M C-type lectin domain family 4, member M
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLTC clathrin, heavy chain (Hc)
CNTNAP2 contactin associated protein-like 2
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL2A1 collagen, type II, alpha 1
COMT catechol-O-methyltransferase
COPS8 COP9 signalosome subunit 8
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CST3 cystatin C
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSK cathepsin K
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DBF4 DBF4 zinc finger
DCLRE1C DNA cross-link repair 1C
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFB1 defensin, beta 1
DIABLO diablo, IAP-binding mitochondrial protein
DICER1 dicer 1, ribonuclease type III
DMD dystrophin
DNM1 dynamin 1
DNM2 dynamin 2
DNTT DNA nucleotidylexotransferase
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DROSHA drosha, ribonuclease type III
DSPP dentin sialophosphoprotein
E2F3 E2F transcription factor 3
EBF1 early B-cell factor 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF3G eukaryotic translation initiation factor 3, subunit G
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ENG endoglin
EPM2AIP1 EPM2A (laforin) interacting protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERP44 endoplasmic reticulum protein 44
ESR1 estrogen receptor 1
ETF1 eukaryotic translation termination factor 1
EXOSC5 exosome component 5
EZR ezrin
F10 coagulation factor X
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F8 coagulation factor VIII, procoagulant component
FAS Fas cell surface death receptor
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCRL5 Fc receptor-like 5
FFAR4 free fatty acid receptor 4
FLNB filamin B, beta
FMR1 fragile X mental retardation 1
FTH1 ferritin, heavy polypeptide 1
FTL ferritin, light polypeptide
FTMT ferritin mitochondrial
FTO fat mass and obesity associated
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GALE UDP-galactose-4-epimerase
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GATA4 GATA binding protein 4
GHRL ghrelin/obestatin prepropeptide
GLP1R glucagon-like peptide 1 receptor
GLRA1 glycine receptor, alpha 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNRHR gonadotropin-releasing hormone receptor
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
GSTA1 glutathione S-transferase alpha 1
GSTA4 glutathione S-transferase alpha 4
GSTM2 glutathione S-transferase mu 2 (muscle)
GUCA1A guanylate cyclase activator 1A (retina)
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HDAC6 histone deacetylase 6
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HINT1 histidine triad nucleotide binding protein 1
HIST3H3 histone cluster 3, H3
HLA-G major histocompatibility complex, class I, G
HMGA1 high mobility group AT-hook 1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HOXA9 homeobox A9
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRAS Harvey rat sarcoma viral oncogene homolog
HTT huntingtin
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL10 interleukin 10
IL1A interleukin 1, alpha
IL6 interleukin 6
IL7 interleukin 7
IPO5 importin 5
IRF4 interferon regulatory factor 4
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KAT5 K(lysine) acetyltransferase 5
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDM4B lysine (K)-specific demethylase 4B
KIF11 kinesin family member 11
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LCAT lecithin-cholesterol acyltransferase
LDHA lactate dehydrogenase A
LDLR low density lipoprotein receptor
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LEP leptin
LIG1 ligase I, DNA, ATP-dependent
LIN28A lin-28 homolog A (C. elegans)
LMNA lamin A/C
LPL lipoprotein lipase
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAOB monoamine oxidase B
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MB21D1 Mab-21 domain containing 1
MDFIC MyoD family inhibitor domain containing
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MECP2 methyl CpG binding protein 2
MEF2C myocyte enhancer factor 2C
MET MET proto-oncogene, receptor tyrosine kinase
MGC16025 uncharacterized LOC85009
MID1 midline 1
MIR107 microRNA 107
MIR127 microRNA 127
MIR200B microRNA 200b
MIR200C microRNA 200c
MIR3201 microRNA 3201
MIR34A microRNA 34a
MIRLET7G microRNA let-7g
MLH1 mutL homolog 1
MMP11 matrix metallopeptidase 11
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MOGAT2 monoacylglycerol O-acyltransferase 2
MPG N-methylpurine-DNA glycosylase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH6 mutS homolog 6
MSTN myostatin
MT-TI tRNA
MT2A metallothionein 2A
MTFMT mitochondrial methionyl-tRNA formyltransferase
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUTYH mutY homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
NAMPT nicotinamide phosphoribosyltransferase
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NBN nibrin
NEK2 NIMA-related kinase 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFYA nuclear transcription factor Y, alpha
NLK nemo-like kinase
NME1 NME/NM23 nucleoside diphosphate kinase 1
NME2 NME/NM23 nucleoside diphosphate kinase 2
NME4 NME/NM23 nucleoside diphosphate kinase 4
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH4 notch 4
NPPB natriuretic peptide B
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NT5C3A 5'-nucleotidase, cytosolic IIIA
NUCLEOLIN nucleolin multifunctional protein
NXF1 nuclear RNA export factor 1
OCLN occludin
OCRL oculocerebrorenal syndrome of Lowe
OGG1 8-oxoguanine DNA glycosylase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPA1 optic atrophy 1 (autosomal dominant)
OPRM1 opioid receptor, mu 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PADI4 peptidyl arginine deiminase, type IV
PAH phenylalanine hydroxylase
PARP1 poly (ADP-ribose) polymerase 1
PAX3 paired box 3
PCLO piccolo presynaptic cytomatrix protein
PCSK1 proprotein convertase subtilisin/kexin type 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PDX1 pancreatic and duodenal homeobox 1
PEPD peptidase D
PFKM phosphofructokinase, muscle
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLK1 polo-like kinase 1
PMP22 peripheral myelin protein 22
PNP purine nucleoside phosphorylase
PNPO pyridoxamine 5'-phosphate oxidase
POLB polymerase (DNA directed), beta
POLG polymerase (DNA directed), gamma
POLH polymerase (DNA directed), eta
POLK polymerase (DNA directed) kappa
POLL polymerase (DNA directed), lambda
POLM polymerase (DNA directed), mu
POLN polymerase (DNA directed) nu
POLQ polymerase (DNA directed), theta
PON1 paraoxonase 1
POU5F1 POU class 5 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRL prolactin
PRNP prion protein
PROM1 prominin 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PURA purine-rich element binding protein A
PURB purine-rich element binding protein B
RAD50 RAD50 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RANBP2 RAN binding protein 2
RBBP8 retinoblastoma binding protein 8
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RHOA ras homolog family member A
RIPK2 receptor-interacting serine-threonine kinase 2
RNU1-4 RNA, U1 small nuclear 4
RPA1 replication protein A1, 70kDa
RPL7 ribosomal protein L7
RPLP1 ribosomal protein, large, P1
RPLP2 ribosomal protein, large, P2
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SAMHD1 SAM domain and HD domain 1
SCARB2 scavenger receptor class B, member 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SELE selectin E
SELPLG selectin P ligand
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFPQ splicing factor proline/glutamine-rich
SFTPB surfactant protein B
SIRT2 sirtuin 2
SIRT4 sirtuin 4
SLC16A12 solute carrier family 16, member 12
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLIT3 slit homolog 3 (Drosophila)
SMAD4 SMAD family member 4
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
SMN2 survival of motor neuron 2, centromeric
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SP1 Sp1 transcription factor
SP100 SP100 nuclear antigen
SPHK2 sphingosine kinase 2
SPI1 Spi-1 proto-oncogene
SPOP speckle-type POZ protein
SRPK1 SRSF protein kinase 1
SRPX sushi-repeat containing protein, X-linked
SRSF10 serine/arginine-rich splicing factor 10
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STAMBP STAM binding protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAU1 staufen double-stranded RNA binding protein 1
SUMO1 small ubiquitin-like modifier 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBK1 TANK-binding kinase 1
TBX5 T-box 5
TERT telomerase reverse transcriptase
TG thyroglobulin
THAP1 THAP domain containing, apoptosis associated protein 1
TK1 thymidine kinase 1, soluble
TMEM173 transmembrane protein 173
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNPO1 transportin 1
TOP1MT topoisomerase (DNA) I, mitochondrial
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TRIM21 tripartite motif containing 21
TRIM5 tripartite motif containing 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPY1 testis specific protein, Y-linked 1
TUSC3 tumor suppressor candidate 3
TYMS thymidylate synthetase
UBE2I ubiquitin-conjugating enzyme E2I
UBE3A ubiquitin protein ligase E3A
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT1A UDP glucuronosyltransferase 1 family, polypeptide A complex locus
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
UHRF1 ubiquitin-like with PHD and ring finger domains 1
USP8 ubiquitin specific peptidase 8
UTF1 undifferentiated embryonic cell transcription factor 1
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VWF von Willebrand factor
WNK2 WNK lysine deficient protein kinase 2
WRN Werner syndrome, RecQ helicase-like
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC6BP1 XRCC6 binding protein 1
YBX1 Y box binding protein 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB38 zinc finger and BTB domain containing 38
ZFP42 ZFP42 zinc finger protein
ZRANB1 zinc finger, RAN-binding domain containing 1
ZW10 zw10 kinetochore protein