egr1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description early growth response 1|The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014] (NCBI Entrez Gene Database, 1958)
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Genes

178 genes co-occuring with the biological term egr1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AGER advanced glycosylation end product-specific receptor
AHR aryl hydrocarbon receptor
AICDA activation-induced cytidine deaminase
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX15 arachidonate 15-lipoxygenase
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
AR androgen receptor
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATF3 activating transcription factor 3
ATF5 activating transcription factor 5
BAG3 BCL2-associated athanogene 3
BCAR1 breast cancer anti-estrogen resistance 1
BIRC5 baculoviral IAP repeat containing 5
CAV1 caveolin 1, caveolae protein, 22kDa
CCKBR cholecystokinin B receptor
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFLAR CASP8 and FADD-like apoptosis regulator
CHGA chromogranin A
CIDEC cell death-inducing DFFA-like effector c
COL1A2 collagen, type I, alpha 2
COL2A1 collagen, type II, alpha 1
CREB1 cAMP responsive element binding protein 1
CREBZF CREB/ATF bZIP transcription factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
E2F1 E2F transcription factor 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
ELAVL1 ELAV like RNA binding protein 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELK1 ELK1, member of ETS oncogene family
ENG endoglin
EPO erythropoietin
ERF Ets2 repressor factor
ETV6 ets variant 6
F13A1 coagulation factor XIII, A1 polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
FASLG Fas ligand (TNF superfamily, member 6)
FGF2 fibroblast growth factor 2 (basic)
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAST gastrin
GATA1 GATA binding protein 1 (globin transcription factor 1)
GDF15 growth differentiation factor 15
GGPS1 geranylgeranyl diphosphate synthase 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GSN gelsolin
HDAC4 histone deacetylase 4
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPK heterogeneous nuclear ribonucleoprotein K
HPSE heparanase
HPSE2 heparanase 2 (inactive)
HRAS Harvey rat sarcoma viral oncogene homolog
HRH1 histamine receptor H1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL1B interleukin 1, beta
IL2RB interleukin 2 receptor, beta
IL4 interleukin 4
IL6 interleukin 6
IPO7 importin 7
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KL klotho
KRT18 keratin 18, type I
KRT19 keratin 19, type I
LDLR low density lipoprotein receptor
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LPAR1 lysophosphatidic acid receptor 1
MAML1 mastermind-like 1 (Drosophila)
MAOB monoamine oxidase B
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MIR106A microRNA 106a
MIR183 microRNA 183
MIR199A1 microRNA 199a-1
MIR20B microRNA 20b
MST1R macrophage stimulating 1 receptor
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDRG1 N-myc downstream regulated 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX2-3 NK2 homeobox 3
NKX3-1 NK3 homeobox 1
NOD2 nucleotide-binding oligomerization domain containing 2
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1I2 nuclear receptor subfamily 1, group I, member 2
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIAS3 protein inhibitor of activated STAT, 3
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLD1 phospholipase D1, phosphatidylcholine-specific
PLK2 polo-like kinase 2
PNPLA2 patatin-like phospholipase domain containing 2
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCD protein kinase C, delta
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROM1 prominin 1
PSEN2 presenilin 2
PTEN phosphatase and tensin homolog
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RIT2 Ras-like without CAAX 2
SAMD9 sterile alpha motif domain containing 9
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SOCS1 suppressor of cytokine signaling 1
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SREBF1 sterol regulatory element binding transcription factor 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TBX21 T-box 21
TBXA2R thromboxane A2 receptor
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TH tyrosine hydroxylase
TMEM8B transmembrane protein 8B
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOE1 target of EGR1, member 1 (nuclear)
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TPH1 tryptophan hydroxylase 1
VEGFA vascular endothelial growth factor A
VIPR2 vasoactive intestinal peptide receptor 2
WT1 Wilms tumor 1
ZFP36 ZFP36 ring finger protein
ZNF300 zinc finger protein 300