ehrlichiosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A primary bacterial infectious disease that results_in infection located_in leukocyte, has_material_basis_in Ehrlichia chaffeensis or Anaplasma phagocytophilum, which are transmitted_by lone start stick and transmitted_by black-legged tick respectively. The infection has_symptom headache, has_symptom muscle aches, has_symptom fatigue and has_symptom rash. (Human Disease Ontology, DOID_10242)
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Genes

145 genes co-occuring with the disease ehrlichiosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
RGR retinal G protein coupled receptor 1.76004
ZAK sterile alpha motif and leucine zipper containing kinase AZK 1.5115
CCDC58 coiled-coil domain containing 58 1.50052
SELPLG selectin P ligand 1.40789
ICK intestinal cell (MAK-like) kinase 1.35115
NUP37 nucleoporin 37kDa 1.33283
MMP12 matrix metallopeptidase 12 1.33109
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 1.13585
VAMP4 vesicle-associated membrane protein 4 0.955361
ATG14 autophagy related 14 0.923387
UCK2 uridine-cytidine kinase 2 0.915551
CD4 CD4 molecule 0.8741
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.869596
ATR ATR serine/threonine kinase 0.860999
ABI1 abl-interactor 1 0.854449
ZC3HC1 zinc finger, C3HC-type containing 1 0.852811
CFLAR CASP8 and FADD-like apoptosis regulator 0.850354
TXNL1 thioredoxin-like 1 0.848307
BCL2A1 BCL2-related protein A1 0.803616
MYD88 myeloid differentiation primary response 88 0.797462
PLEC plectin 0.788442
TNF tumor necrosis factor 0.785574
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.784755
ZFYVE1 zinc finger, FYVE domain containing 1 0.757786
FSCN2 fascin actin-bundling protein 2, retinal 0.757378
CS citrate synthase 0.751678
DNASE1L1 deoxyribonuclease I-like 1 0.732596
IL10 interleukin 10 0.729357
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 0.716425
CXCR2 chemokine (C-X-C motif) receptor 2 0.691896
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.690694
DEFB1 defensin, beta 1 0.685091
CXCL2 chemokine (C-X-C motif) ligand 2 0.683493
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.669538
CXCL8 chemokine (C-X-C motif) ligand 8 0.666755
DEFB104B defensin, beta 104B 0.658818
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 0.636315
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.631991
PRG1 p53-responsive gene 1 0.624927
IER3 immediate early response 3 0.606152
STX16 syntaxin 16 0.595233
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.592116
BIRC3 baculoviral IAP repeat containing 3 0.5645
NOD1 nucleotide-binding oligomerization domain containing 1 0.560227
TLR2 toll-like receptor 2 0.530381
SAMM50 SAMM50 sorting and assembly machinery component 0.506123
RENBP renin binding protein 0.506123
APOPT1 apoptogenic 1, mitochondrial 0.505356
IL1B interleukin 1, beta 0.495029
PRKCD protein kinase C, delta 0.48893
CRP C-reactive protein, pentraxin-related 0.486646
IFNG interferon, gamma 0.485885
STAT1 signal transducer and activator of transcription 1, 91kDa 0.482844
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.482464
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 0.476014
HES4 hes family bHLH transcription factor 4 0.472225
CUX1 cut-like homeobox 1 0.468441
IL18R1 interleukin 18 receptor 1 0.465038
PYCARD PYD and CARD domain containing 0.454093
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.438282
SRRM1 serine/arginine repetitive matrix 1 0.434899
CXCR1 chemokine (C-X-C motif) receptor 1 0.431519
ANK1 ankyrin 1, erythrocytic 0.428891
TFRC transferrin receptor 0.426265
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.425139
NLRP12 NLR family, pyrin domain containing 12 0.419892
REV1 REV1, polymerase (DNA directed) 0.415773
DLD dihydrolipoamide dehydrogenase 0.413153
GNG8 guanine nucleotide binding protein (G protein), gamma 8 0.398962
LAMP1 lysosomal-associated membrane protein 1 0.395608
IL1R2 interleukin 1 receptor, type II 0.393746
SPI1 Spi-1 proto-oncogene 0.391513
RIPK2 receptor-interacting serine-threonine kinase 2 0.387051
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.382223
DUT deoxyuridine triphosphatase 0.373698
NLRP1 NLR family, pyrin domain containing 1 0.371847
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.364824
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.348981
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 0.33651
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.328105
GADD45B growth arrest and DNA-damage-inducible, beta 0.323365
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.320817
TLR4 toll-like receptor 4 0.312827
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.311739
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.309928
STAB2 stabilin 2 0.303059
CXCR6 chemokine (C-X-C motif) receptor 6 0.301254
DEFB4A defensin, beta 4A 0.294053
MATK megakaryocyte-associated tyrosine kinase 0.290821
NSF N-ethylmaleimide-sensitive factor 0.284013
IFT122 intraflagellar transport 122 0.274376
MAP2K3 mitogen-activated protein kinase kinase 3 0.273664
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.267622
BECN1 beclin 1, autophagy related 0.266558
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.261245
M6PR mannose-6-phosphate receptor (cation dependent) 0.259124
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.255946
CXCL9 chemokine (C-X-C motif) ligand 9 0.246799
CCKAR cholecystokinin A receptor 0.240148
CYBB cytochrome b-245, beta polypeptide 0.238752
SELL selectin L 0.238054
CCL2 chemokine (C-C motif) ligand 2 0.234573
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.234573
NOD2 nucleotide-binding oligomerization domain containing 2 0.231102
PLIN1 perilipin 1 0.227642
IL1A interleukin 1, alpha 0.226952
CCL7 chemokine (C-C motif) ligand 7 0.218715
ANO1 anoctamin 1, calcium activated chloride channel 0.210925
IL1R1 interleukin 1 receptor, type I 0.204593
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.196139
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.194548
PNLIP pancreatic lipase 0.192344
PRSS21 protease, serine, 21 (testisin) 0.190476
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.190168
CLDN4 claudin 4 0.189859
IGF2R insulin-like growth factor 2 receptor 0.177301
NTN1 netrin 1 0.176757
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.174881
BAX BCL2-associated X protein 0.168854
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.168148
CENPV centromere protein V 0.165874
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.162707
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.161716
ALB albumin 0.158951
LGALS4 lectin, galactoside-binding, soluble, 4 0.142989
HTRA1 HtrA serine peptidase 1 0.142544
CXCL13 chemokine (C-X-C motif) ligand 13 0.14248
CCR1 chemokine (C-C motif) receptor 1 0.142073
CCL20 chemokine (C-C motif) ligand 20 0.141802
IRF1 interferon regulatory factor 1 0.141749
JAK1 Janus kinase 1 0.141071
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.139608
ILK integrin-linked kinase 0.138602
GSTM2 glutathione S-transferase mu 2 (muscle) 0.13811
CCL5 chemokine (C-C motif) ligand 5 0.138001
NPC1 Niemann-Pick disease, type C1 0.137863
CCR2 chemokine (C-C motif) receptor 2 0.136859
UVRAG UV radiation resistance associated 0.136152
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.136099
CTSL cathepsin L 0.13581
CARD17 caspase recruitment domain family, member 17 0.135257
CALR calreticulin 0.135198
CYGB cytoglobin 0.134708
CD63 CD63 molecule 0.134408
HBD hemoglobin, delta 0.134343