ei24 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description etoposide induced 2.4|This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014] (NCBI Entrez Gene Database, 9538)
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Genes

5 genes co-occuring with the biological term ei24 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CHEK1 checkpoint kinase 1
E2F1 E2F transcription factor 1
EI24 etoposide induced 2.4
KPNB1 karyopherin (importin) beta 1
TP53 tumor protein p53