eif2ak2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description eukaryotic translation initiation factor 2-alpha kinase 2|The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] (NCBI Entrez Gene Database, 5610)
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Genes

2 genes co-occuring with the biological term eif2ak2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)