eldeline-3750 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the eldeline-3750 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
AKR1C4 aldo-keto reductase family 1, member C4
ALDOB aldolase B, fructose-bisphosphate
ASCL1 achaete-scute family bHLH transcription factor 1
ATP10A ATPase, class V, type 10A
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP9B ATPase, class II, type 9B
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C10ORF10 chromosome 10 open reading frame 10
C2 complement component 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CARTPT CART prepropeptide
CDK20 cyclin-dependent kinase 20
CLDN9 claudin 9
CLEC4E C-type lectin domain family 4, member E
CNGB3 cyclic nucleotide gated channel beta 3
COLEC11 collectin sub-family member 11
CORO7 coronin 7
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREBZF CREB/ATF bZIP transcription factor
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DOK5 docking protein 5
EGR1 early growth response 1
EMID1 EMI domain containing 1
FABP6 fatty acid binding protein 6, ileal
FASLG Fas ligand (TNF superfamily, member 6)
FRZB frizzled-related protein
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GAS7 growth arrest-specific 7
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GHRHR growth hormone releasing hormone receptor
GJA8 gap junction protein, alpha 8, 50kDa
GRIK2 glutamate receptor, ionotropic, kainate 2
HCRP1 hepatocellular carcinoma-related HCRP1
IFFO1 intermediate filament family orphan 1
IL36G interleukin 36, gamma
IRF4 interferon regulatory factor 4
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KANK1 KN motif and ankyrin repeat domains 1
KDM4C lysine (K)-specific demethylase 4C
KEL Kell blood group, metallo-endopeptidase
KLHL25 kelch-like family member 25
LGSN lengsin, lens protein with glutamine synthetase domain
LRRN2 leucine rich repeat neuronal 2
MEFV Mediterranean fever
MFAP3L microfibrillar-associated protein 3-like
MIER2 mesoderm induction early response 1, family member 2
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MMP11 matrix metallopeptidase 11
MMP13 matrix metallopeptidase 13
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUC7 mucin 7, secreted
MYH15 myosin, heavy chain 15
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MYOZ1 myozenin 1
NEK9 NIMA-related kinase 9
NEUROD1 neuronal differentiation 1
NF1 neurofibromin 1
NLRP3 NLR family, pyrin domain containing 3
NNMT nicotinamide N-methyltransferase
NOS3 nitric oxide synthase 3 (endothelial cell)
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NUDC nudC nuclear distribution protein
NUMA1 nuclear mitotic apparatus protein 1
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
OSGIN2 oxidative stress induced growth inhibitor family member 2
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE8B phosphodiesterase 8B
PKNOX1 PBX/knotted 1 homeobox 1
PMFBP1 polyamine modulated factor 1 binding protein 1
RAB6B RAB6B, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RIF1 replication timing regulatory factor 1
RNF185 ring finger protein 185
RNF208 ring finger protein 208
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SFRP4 secreted frizzled-related protein 4
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SRSF7 serine/arginine-rich splicing factor 7
SULT4A1 sulfotransferase family 4A, member 1
SV2B synaptic vesicle glycoprotein 2B
TEF thyrotrophic embryonic factor
TFDP3 transcription factor Dp family, member 3
TMEM180 transmembrane protein 180
TSGA10 testis specific, 10
TTC12 tetratricopeptide repeat domain 12
USP29 ubiquitin specific peptidase 29
USP46 ubiquitin specific peptidase 46
VPRBP Vpr (HIV-1) binding protein
WNT2 wingless-type MMTV integration site family member 2
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZER1 zyg-11 related, cell cycle regulator
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAP2 ArfGAP with dual PH domains 2
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARC activity-regulated cytoskeleton-associated protein
ARMC4 armadillo repeat containing 4
ARPIN actin-related protein 2/3 complex inhibitor
ASAP1-IT1 ASAP1 intronic transcript 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BCL9 B-cell CLL/lymphoma 9
CCNJL cyclin J-like
CD79B CD79b molecule, immunoglobulin-associated beta
CHM choroideremia (Rab escort protein 1)
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CORT cortistatin
CPZ carboxypeptidase Z
CYB5R2 cytochrome b5 reductase 2
DCAF13 DDB1 and CUL4 associated factor 13
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DPF3 D4, zinc and double PHD fingers, family 3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ENOX1 ecto-NOX disulfide-thiol exchanger 1
F11R F11 receptor
FAM120C family with sequence similarity 120C
FAM184A family with sequence similarity 184, member A
FAM186A family with sequence similarity 186, member A
FBXW12 F-box and WD repeat domain containing 12
FGL1 fibrinogen-like 1
FKBP10 FK506 binding protein 10, 65 kDa
GDAP1 ganglioside induced differentiation associated protein 1
GRAMD1C GRAM domain containing 1C
HDAC7 histone deacetylase 7
HIST1H1D histone cluster 1, H1d
HIST1H2AM histone cluster 1, H2am
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IQSEC2 IQ motif and Sec7 domain 2
ITPKA inositol-trisphosphate 3-kinase A
KIAA1107 KIAA1107
KIFC1 kinesin family member C1
LMBR1L limb development membrane protein 1-like
LMCD1 LIM and cysteine-rich domains 1
LMNB1 lamin B1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC729164 hCG1732469
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MFSD10 major facilitator superfamily domain containing 10
MOCS3 molybdenum cofactor synthesis 3
MX1 MX dynamin-like GTPase 1
MYO19 myosin XIX
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PEX26 peroxisomal biogenesis factor 26
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLCD1 phospholipase C, delta 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPL periplakin
PRKCE protein kinase C, epsilon
PRPH peripherin
PRR15L proline rich 15-like
PSD4 pleckstrin and Sec7 domain containing 4
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RFX7 regulatory factor X, 7
RIBC2 RIB43A domain with coiled-coils 2
RNF122 ring finger protein 122
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
SCIN scinderin
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SGK2 serum/glucocorticoid regulated kinase 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
STK16 serine/threonine kinase 16
SYTL2 synaptotagmin-like 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAOK1 TAO kinase 1
TRAC T cell receptor alpha constant
TSPYL2 TSPY-like 2
TTLL7 tubulin tyrosine ligase-like family member 7
USP20 ubiquitin specific peptidase 20
VASP vasodilator-stimulated phosphoprotein
VEZT vezatin, adherens junctions transmembrane protein
VGF VGF nerve growth factor inducible
ZNF140 zinc finger protein 140
ZNF268 zinc finger protein 268
ZNF286A zinc finger protein 286A
ZNF711 zinc finger protein 711
ZNF770 zinc finger protein 770
ZNF778 zinc finger protein 778