elderly Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

263 genes co-occuring with the biological term elderly in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
ADRBK1 adrenergic, beta, receptor kinase 1
AFP alpha-fetoprotein
AGTR1 angiotensin II receptor, type 1
AHSG alpha-2-HS-glycoprotein
AICDA activation-induced cytidine deaminase
AKTIP AKT interacting protein
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APOA1 apolipoprotein A-I
APOA4 apolipoprotein A-IV
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP4 aquaporin 4
AR androgen receptor
ARMS2 age-related maculopathy susceptibility 2
ATP10D ATPase, class V, type 10D
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
AVP arginine vasopressin
BCL2 B-cell CLL/lymphoma 2
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP2 bone morphogenetic protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
C9ORF72 chromosome 9 open reading frame 72
CASR calcium-sensing receptor
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD27 CD27 molecule
CD28 CD28 molecule
CD4 CD4 molecule
CD68 CD68 molecule
CD8A CD8a molecule
CETP cholesteryl ester transfer protein, plasma
CFH complement factor H
CFLAR CASP8 and FADD-like apoptosis regulator
CHIT1 chitinase 1 (chitotriosidase)
CIITA class II, major histocompatibility complex, transactivator
CLEC16A C-type lectin domain family 16, member A
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COMT catechol-O-methyltransferase
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CREBBP CREB binding protein
CRP C-reactive protein, pentraxin-related
CST3 cystatin C
CTSS cathepsin S
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DCN decorin
DDAH1 dimethylarginine dimethylaminohydrolase 1
DIO1 deiodinase, iodothyronine, type I
DIO2 deiodinase, iodothyronine, type II
DKK3 dickkopf WNT signaling pathway inhibitor 3
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
EGFR epidermal growth factor receptor
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F10 coagulation factor X
F12 coagulation factor XII (Hageman factor)
F2 coagulation factor II (thrombin)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FABP2 fatty acid binding protein 2, intestinal
FAS Fas cell surface death receptor
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGF23 fibroblast growth factor 23
FLG filaggrin
FLT3 fms-related tyrosine kinase 3
FMR1 fragile X mental retardation 1
FNDC5 fibronectin type III domain containing 5
FOXP3 forkhead box P3
GCG glucagon
GDF15 growth differentiation factor 15
GDF5 growth differentiation factor 5
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GLA galactosidase, alpha
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRM7 glutamate receptor, metabotropic 7
GRN granulin
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GYS1 glycogen synthase 1 (muscle)
HBA1 hemoglobin, alpha 1
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
HSPB1 heat shock 27kDa protein 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTRA1 HtrA serine peptidase 1
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
INSIG2 insulin induced gene 2
IRS2 insulin receptor substrate 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
IVL involucrin
JAK2 Janus kinase 2
KIF6 kinesin family member 6
KL klotho
KNG1 kininogen 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMA5 laminin, alpha 5
LCT lactase
LDHA lactate dehydrogenase A
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LMNA lamin A/C
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LRRK2 leucine-rich repeat kinase 2
LTA lymphotoxin alpha
LTF lactotransferrin
MAPT microtubule-associated protein tau
MGMT O-6-methylguanine-DNA methyltransferase
MGP matrix Gla protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR499A microRNA 499a
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MMP9 matrix metallopeptidase 9
MRC1 mannose receptor, C type 1
MSH3 mutS homolog 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NF2 neurofibromin 2 (merlin)
NGF nerve growth factor (beta polypeptide)
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPY2R neuropeptide Y receptor Y2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPRD1 opioid receptor, delta 1
PDYN prodynorphin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAUR plasminogen activator, urokinase receptor
PON1 paraoxonase 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTPRC protein tyrosine phosphatase, receptor type, C
RBP4 retinol binding protein 4, plasma
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RETN resistin
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RXRB retinoid X receptor, beta
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SELE selectin E
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINA13P serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOST sclerostin
SP1 Sp1 transcription factor
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TACR3 tachykinin receptor 3
TARDBP TAR DNA binding protein
TAS2R50 taste receptor, type 2, member 50
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNNI3 troponin I type 3 (cardiac)
TNNT1 troponin T type 1 (skeletal, slow)
TNNT2 troponin T type 2 (cardiac)
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TP53 tumor protein p53
TPH1 tryptophan hydroxylase 1
TSHR thyroid stimulating hormone receptor
TTR transthyretin
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
UNC93B1 unc-93 homolog B1 (C. elegans)
VAMP8 vesicle-associated membrane protein 8
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIPR1 vasoactive intestinal peptide receptor 1
VWF von Willebrand factor
WWC1 WW and C2 domain containing 1
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1