elevation Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

419 genes co-occuring with the biological term elevation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACACB acetyl-CoA carboxylase beta
ACE angiotensin I converting enzyme
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM2 adrenomedullin 2
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
ADRBK1 adrenergic, beta, receptor kinase 1
AFP alpha-fetoprotein
AGER advanced glycosylation end product-specific receptor
AGR2 anterior gradient 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHCY adenosylhomocysteinase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALOX12 arachidonate 12-lipoxygenase
ALPL alkaline phosphatase, liver/bone/kidney
AMY1A amylase, alpha 1A (salivary)
ANPEP alanyl (membrane) aminopeptidase
AOC3 amine oxidase, copper containing 3
APAF1 apoptotic peptidase activating factor 1
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APP amyloid beta (A4) precursor protein
AQP2 aquaporin 2 (collecting duct)
AQP4 aquaporin 4
AR androgen receptor
ARF6 ADP-ribosylation factor 6
ARMS2 age-related maculopathy susceptibility 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATM ATM serine/threonine kinase
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
AVP arginine vasopressin
AVPR2 arginine vasopressin receptor 2
B2M beta-2-microglobulin
BACE1 beta-site APP-cleaving enzyme 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BDNF brain-derived neurotrophic factor
BIK BCL2-interacting killer (apoptosis-inducing)
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP7 bone morphogenetic protein 7
C4B complement component 4B (Chido blood group)
CALCA calcitonin-related polypeptide alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CATSPER1 cation channel, sperm associated 1
CBS cystathionine-beta-synthase
CCL17 chemokine (C-C motif) ligand 17
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CD14 CD14 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD59 CD59 molecule, complement regulatory protein
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDX2 caudal type homeobox 2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CERS6 ceramide synthase 6
CETP cholesteryl ester transfer protein, plasma
CGB chorionic gonadotropin, beta polypeptide
CHIT1 chitinase 1 (chitotriosidase)
CKBE creatine kinase, ectopic expression
CKM creatine kinase, muscle
COCH cochlin
COL3A1 collagen, type III, alpha 1
COMP cartilage oligomeric matrix protein
COMT catechol-O-methyltransferase
CPB2 carboxypeptidase B2 (plasma)
CRABP1 cellular retinoic acid binding protein 1
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CRP C-reactive protein, pentraxin-related
CS citrate synthase
CSF1 colony stimulating factor 1 (macrophage)
CST3 cystatin C
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSG cathepsin G
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DEFB4A defensin, beta 4A
DEGS1 delta(4)-desaturase, sphingolipid 1
DNER delta/notch-like EGF repeat containing
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
E2F3 E2F transcription factor 3
EDAR ectodysplasin A receptor
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
ELANE elastase, neutrophil expressed
ELAVL1 ELAV like RNA binding protein 1
ENG endoglin
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EVPL envoplakin
F2 coagulation factor II (thrombin)
F2RL3 coagulation factor II (thrombin) receptor-like 3
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FABP4 fatty acid binding protein 4, adipocyte
FADD Fas (TNFRSF6)-associated via death domain
FANCL Fanconi anemia, complementation group L
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGF23 fibroblast growth factor 23
FGFR3 fibroblast growth factor receptor 3
FOXO1 forkhead box O1
FOXP3 forkhead box P3
FTH1 ferritin, heavy polypeptide 1
FTL ferritin, light polypeptide
FXN frataxin
GALR2 galanin receptor 2
GDF15 growth differentiation factor 15
GFAP glial fibrillary acidic protein
GGT1 gamma-glutamyltransferase 1
GHRL ghrelin/obestatin prepropeptide
GLA galactosidase, alpha
GLI1 GLI family zinc finger 1
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GPX3 glutathione peroxidase 3
GRN granulin
GSK3A glycogen synthase kinase 3 alpha
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HBG1 hemoglobin, gamma A
HDC histidine decarboxylase
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HPGDS hematopoietic prostaglandin D synthase
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
HSPB1 heat shock 27kDa protein 1
HTRA1 HtrA serine peptidase 1
HTRA3 HtrA serine peptidase 3
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDO1 indoleamine 2,3-dioxygenase 1
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGFBP1 insulin-like growth factor binding protein 1
IGFBP4 insulin-like growth factor binding protein 4
IL10 interleukin 10
IL12A interleukin 12A
IL13 interleukin 13
IL15 interleukin 15
IL16 interleukin 16
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL22 interleukin 22
IL2RA interleukin 2 receptor, alpha
IL33 interleukin 33
IL33R interleukin 33 receptor
IL6 interleukin 6
IL7 interleukin 7
ILK integrin-linked kinase
ING4 inhibitor of growth family, member 4
INS insulin
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KDR kinase insert domain receptor
KIF21A kinesin family member 21A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
KLK3 kallikrein-related peptidase 3
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRT18 keratin 18, type I
LASP1 LIM and SH3 protein 1
LATS2 large tumor suppressor kinase 2
LCN2 lipocalin 2
LCT lactase
LDHB lactate dehydrogenase B
LDLR low density lipoprotein receptor
LEP leptin
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS9 lectin, galactoside-binding, soluble, 9
LIPC lipase, hepatic
LOX lysyl oxidase
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LRRK2 leucine-rich repeat kinase 2
LTB4R leukotriene B4 receptor
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAG myelin associated glycoprotein
MAOB monoamine oxidase B
MAPK14 mitogen-activated protein kinase 14
MAPT microtubule-associated protein tau
MARK4 MAP/microtubule affinity-regulating kinase 4
MASP2 mannan-binding lectin serine peptidase 2
MBD2 methyl-CpG binding domain protein 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCAM melanoma cell adhesion molecule
MDK midkine (neurite growth-promoting factor 2)
MDM4 MDM4, p53 regulator
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR155 microRNA 155
MIR181A2 microRNA 181a-2
MIR205 microRNA 205
MIR210 microRNA 210
MIR34A microRNA 34a
MIR499A microRNA 499a
MIR92A1 microRNA 92a-1
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MT-CYB cytochrome b
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYH9 myosin, heavy chain 9, non-muscle
MYLIP myosin regulatory light chain interacting protein
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAMPT nicotinamide phosphoribosyltransferase
NCR1 natural cytotoxicity triggering receptor 1
NDEL1 nudE neurodevelopment protein 1-like 1
NF1 neurofibromin 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLRP3 NLR family, pyrin domain containing 3
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPEPPS aminopeptidase puromycin sensitive
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPY neuropeptide Y
NQO1 NAD(P)H dehydrogenase, quinone 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OXTR oxytocin receptor
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAWR PRKC, apoptosis, WT1, regulator
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCSK9 proprotein convertase subtilisin/kexin type 9
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDYN prodynorphin
PFN1 profilin 1
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLTP phospholipid transfer protein
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNPLA3 patatin-like phospholipase domain containing 3
PON1 paraoxonase 1
POU2F1 POU class 2 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPL periplakin
PRAME preferentially expressed antigen in melanoma
PRF1 perforin 1 (pore forming protein)
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PRSS2 protease, serine, 2 (trypsin 2)
PSEN1 presenilin 1
PTGDR prostaglandin D2 receptor (DP)
PTGDR2 prostaglandin D2 receptor 2
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTK2 protein tyrosine kinase 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTX3 pentraxin 3, long
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RARA retinoic acid receptor, alpha
RASA4 RAS p21 protein activator 4
RBP4 retinol binding protein 4, plasma
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RUNX2 runt-related transcription factor 2
RYR2 ryanodine receptor 2 (cardiac)
S100B S100 calcium binding protein B
S100G S100 calcium binding protein G
SAA1 serum amyloid A1
SARAF store-operated calcium entry-associated regulatory factor
SCN5A sodium channel, voltage gated, type V alpha subunit
SDC1 syndecan 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIRT1 sirtuin 1
SKIL SKI-like proto-oncogene
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMS spermine synthase
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOAT1 sterol O-acyltransferase 1
SOD2 superoxide dismutase 2, mitochondrial
SOST sclerostin
SP1 Sp1 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRSF3 serine/arginine-rich splicing factor 3
ST2 suppression of tumorigenicity 2
STMN2 stathmin 2
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SYK spleen tyrosine kinase
TARDBP TAR DNA binding protein
TEAD4 TEA domain family member 4
TERF2 telomeric repeat binding factor 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBD thrombomodulin
TIMP1 TIMP metallopeptidase inhibitor 1
TLK1 tousled-like kinase 1
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53
TP63 tumor protein p63
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSHR thyroid stimulating hormone receptor
TSLP thymic stromal lymphopoietin
UBIAD1 UbiA prenyltransferase domain containing 1
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
USF1 upstream transcription factor 1
UTS2 urotensin 2
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VNN1 vanin 1
VTRNA2-1 vault RNA 2-1
VWF von Willebrand factor
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
XDH xanthine dehydrogenase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YY1AP1 YY1 associated protein 1
ZPR1 ZPR1 zinc finger