elk1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description ELK1, member of ETS oncogene family|This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 2002)
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Genes

75 genes co-occuring with the biological term elk1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AR androgen receptor
ATF4 activating transcription factor 4
ATF5 activating transcription factor 5
AURKA aurora kinase A
BLVRA biliverdin reductase A
BRAF B-Raf proto-oncogene, serine/threonine kinase
DDIT3 DNA-damage-inducible transcript 3
EGF epidermal growth factor
EGR1 early growth response 1
ELK1 ELK1, member of ETS oncogene family
EPAS1 endothelial PAS domain protein 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV4 ets variant 4
FADS2 fatty acid desaturase 2
FBXO25 F-box protein 25
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGF2 fibroblast growth factor 2 (basic)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GHSR growth hormone secretagogue receptor
GRPR gastrin-releasing peptide receptor
HLX H2.0-like homeobox
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
INS insulin
JUN jun proto-oncogene
KIAA1524 KIAA1524
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MCL1 myeloid cell leukemia 1
MED23 mediator complex subunit 23
MIR200B microRNA 200b
MIRLET7A1 microRNA let-7a-1
MISO1 mitochondrial inner membrane subdomain organizer 1
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MZF1 myeloid zinc finger 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS2 nitric oxide synthase 2, inducible
NR1I3 nuclear receptor subfamily 1, group I, member 3
PADI4 peptidyl arginine deiminase, type IV
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCG1 phospholipase C, gamma 1
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCH protein kinase C, eta
PTK2 protein tyrosine kinase 2
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RIT1 Ras-like without CAAX 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RUNX1 runt-related transcription factor 1
SENP1 SUMO1/sentrin specific peptidase 1
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLPI secretory leukocyte peptidase inhibitor
SLU7 SLU7 splicing factor homolog (S. cerevisiae)
SRF serum response factor (c-fos serum response element-binding transcription factor)
TBP TATA box binding protein
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
UBE2I ubiquitin-conjugating enzyme E2I
VIL1 villin 1
ZFP36 ZFP36 ring finger protein