ellipticine-5779 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the ellipticine-5779 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AQP3 aquaporin 3 (Gill blood group)
ARC activity-regulated cytoskeleton-associated protein
ATF3 activating transcription factor 3
BAMBI BMP and activin membrane-bound inhibitor
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BTG2 BTG family, member 2
C10ORF10 chromosome 10 open reading frame 10
C9 complement component 9
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC14A cell division cycle 14A
CDHR2 cadherin-related family member 2
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CHGA chromogranin A
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CRABP2 cellular retinoic acid binding protein 2
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DIO3 deiodinase, iodothyronine, type III
DLX2 distal-less homeobox 2
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EDN1 endothelin 1
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EPHA4 EPH receptor A4
FGF18 fibroblast growth factor 18
FGR FGR proto-oncogene, Src family tyrosine kinase
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
HEXIM1 hexamethylene bis-acetamide inducible 1
HOOK1 hook microtubule-tethering protein 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL6 interleukin 6
KCNIP1 Kv channel interacting protein 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LAMA2 laminin, alpha 2
LBH limb bud and heart development
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MC5R melanocortin 5 receptor
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP10 matrix metallopeptidase 10
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NEFH neurofilament, heavy polypeptide
NEFM neurofilament, medium polypeptide
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPTX2 neuronal pentraxin II
NR4A2 nuclear receptor subfamily 4, group A, member 2
NSUN6 NOP2/Sun domain family, member 6
NUP88 nucleoporin 88kDa
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PAIP2B poly(A) binding protein interacting protein 2B
PCDH9 protocadherin 9
PITX2 paired-like homeodomain 2
PLIN2 perilipin 2
PNMAL1 paraneoplastic Ma antigen family-like 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRB3 proline-rich protein BstNI subfamily 3
PTHLH parathyroid hormone-like hormone
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RGCC regulator of cell cycle
RGS16 regulator of G-protein signaling 16
RGS4 regulator of G-protein signaling 4
RIMS3 regulating synaptic membrane exocytosis 3
RND1 Rho family GTPase 1
RPL10L ribosomal protein L10-like
SAT1 spermidine/spermine N1-acetyltransferase 1
SELPLG selectin P ligand
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SGK1 serum/glucocorticoid regulated kinase 1
SLC16A4 solute carrier family 16, member 4
SLC16A6 solute carrier family 16, member 6
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SMAD5-AS1 SMAD5 antisense RNA 1
SNAI1 snail family zinc finger 1
SPAG8 sperm associated antigen 8
STC1 stanniocalcin 1
SYT17 synaptotagmin XVII
TEX14 testis expressed 14
TMOD1 tropomodulin 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM29 tripartite motif containing 29
TRIM49 tripartite motif containing 49
ZNF224 zinc finger protein 224

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ADRB2 adrenoceptor beta 2, surface
AEN apoptosis enhancing nuclease
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARID4A AT rich interactive domain 4A (RBP1-like)
ARMC7 armadillo repeat containing 7
ASAP1-IT1 ASAP1 intronic transcript 1
ASTE1 asteroid homolog 1 (Drosophila)
ATXN7L3B ataxin 7-like 3B
BANP BTG3 associated nuclear protein
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BYSL bystin-like
C10ORF88 chromosome 10 open reading frame 88
C2ORF44 chromosome 2 open reading frame 44
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDCA4 cell division cycle associated 4
CENPC centromere protein C
CLDN4 claudin 4
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOLK dolichol kinase
E2F6 E2F transcription factor 6
EFNA1 ephrin-A1
EFNA4 ephrin-A4
ERCC6L excision repair cross-complementation group 6-like
FADD Fas (TNFRSF6)-associated via death domain
FBXL2 F-box and leucine-rich repeat protein 2
FKBPL FK506 binding protein like
FZD8 frizzled class receptor 8
GEMIN4 gem (nuclear organelle) associated protein 4
GSPT2 G1 to S phase transition 2
HAUS3 HAUS augmin-like complex, subunit 3
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HJURP Holliday junction recognition protein
HMGA2 high mobility group AT-hook 2
HMGXB4 HMG box domain containing 4
IER2 immediate early response 2
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
JMJD4 jumonji domain containing 4
KIAA0753 KIAA0753
KLHL9 kelch-like family member 9
LMNB1 lamin B1
LRRC8E leucine rich repeat containing 8 family, member E
MAPK6 mitogen-activated protein kinase 6
MED17 mediator complex subunit 17
MED7 mediator complex subunit 7
MGA MGA, MAX dimerization protein
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
MSL2 male-specific lethal 2 homolog (Drosophila)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
PCTP phosphatidylcholine transfer protein
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RANBP6 RAN binding protein 6
REV1 REV1, polymerase (DNA directed)
RIOK2 RIO kinase 2
RLF rearranged L-myc fusion
RNMTL1 RNA methyltransferase like 1
RPP38 ribonuclease P/MRP 38kDa subunit
RUFY2 RUN and FYVE domain containing 2
SCAF8 SR-related CTD-associated factor 8
SLC38A2 solute carrier family 38, member 2
SPATA2L spermatogenesis associated 2-like
SPEG SPEG complex locus
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TBK1 TANK-binding kinase 1
TGS1 trimethylguanosine synthase 1
TRIB1 tribbles pseudokinase 1
TRIM13 tripartite motif containing 13
TRIM32 tripartite motif containing 32
TRIM68 tripartite motif containing 68
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
WDR5B WD repeat domain 5B
ZBED8 zinc finger, BED-type containing 8
ZBTB24 zinc finger and BTB domain containing 24
ZBTB44 zinc finger and BTB domain containing 44
ZNF107 zinc finger protein 107
ZNF112 zinc finger protein 112
ZNF134 zinc finger protein 134
ZNF14 zinc finger protein 14
ZNF232 zinc finger protein 232
ZNF273 zinc finger protein 273
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF324 zinc finger protein 324
ZNF443 zinc finger protein 443
ZNF552 zinc finger protein 552
ZNF557 zinc finger protein 557
ZNF623 zinc finger protein 623
ZNF675 zinc finger protein 675
ZNF696 zinc finger protein 696
ZNF8 zinc finger protein 8
ZNF85 zinc finger protein 85
ZXDC ZXD family zinc finger C