| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the ellipticine-6253 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA1 | actin, alpha 1, skeletal muscle |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADM | adrenomedullin |
| APOA1 | apolipoprotein A-I |
| APOE | apolipoprotein E |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ATF3 | activating transcription factor 3 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CACYBP | calcyclin binding protein |
| CCKAR | cholecystokinin A receptor |
| CCND2 | cyclin D2 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| COL14A1 | collagen, type XIV, alpha 1 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTGF | connective tissue growth factor |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DLX2 | distal-less homeobox 2 |
| DOC2B | double C2-like domains, beta |
| DUSP4 | dual specificity phosphatase 4 |
| EFHD1 | EF-hand domain family, member D1 |
| EGR1 | early growth response 1 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FAM46C | family with sequence similarity 46, member C |
| FGF18 | fibroblast growth factor 18 |
| FGF3 | fibroblast growth factor 3 |
| FH | fumarate hydratase |
| FSCN1 | fascin actin-bundling protein 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GLS | glutaminase |
| H3F3B | H3 histone, family 3B (H3.3B) |
| HBEGF | heparin-binding EGF-like growth factor |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IRS2 | insulin receptor substrate 2 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KLF9 | Kruppel-like factor 9 |
| LOC399491 | |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MAP4 | microtubule-associated protein 4 |
| MED14 | mediator complex subunit 14 |
| METTL7A | methyltransferase like 7A |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MSX1 | msh homeobox 1 |
| MTA1 | metastasis associated 1 |
| MTSS1 | metastasis suppressor 1 |
| NF2 | neurofibromin 2 (merlin) |
| NHLH2 | nescient helix loop helix 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPTX1 | neuronal pentraxin I |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| ONECUT2 | one cut homeobox 2 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEK | pleckstrin |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTMS | parathymosin |
| PTRF | polymerase I and transcript release factor |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| RGCC | regulator of cell cycle |
| RUFY3 | RUN and FYVE domain containing 3 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SUGP1 | SURP and G patch domain containing 1 |
| SUMO1 | small ubiquitin-like modifier 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TAT | tyrosine aminotransferase |
| TOX4 | TOX high mobility group box family member 4 |
| TTC33 | tetratricopeptide repeat domain 33 |
| VAX2 | ventral anterior homeobox 2 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADNP | activity-dependent neuroprotector homeobox |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARMC7 | armadillo repeat containing 7 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| ATF4 | activating transcription factor 4 |
| BANP | BTG3 associated nuclear protein |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BYSL | bystin-like |
| C17ORF62 | chromosome 17 open reading frame 62 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| C7ORF49 | chromosome 7 open reading frame 49 |
| CCNL1 | cyclin L1 |
| CDCA4 | cell division cycle associated 4 |
| CENPE | centromere protein E, 312kDa |
| CLDN4 | claudin 4 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| COIL | coilin |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| E2F6 | E2F transcription factor 6 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFNA4 | ephrin-A4 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM50B | family with sequence similarity 50, member B |
| FBXO34 | F-box protein 34 |
| FOXA1 | forkhead box A1 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HAUS3 | HAUS augmin-like complex, subunit 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HJURP | Holliday junction recognition protein |
| HOXC6 | homeobox C6 |
| HSPA8 | heat shock 70kDa protein 8 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IFRD1 | interferon-related developmental regulator 1 |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| LOC100272216 | uncharacterized LOC100272216 |
| MCRS1 | microspherule protein 1 |
| MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit |
| NCK1 | NCK adaptor protein 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PGS1 | phosphatidylglycerophosphate synthase 1 |
| PLK2 | polo-like kinase 2 |
| PNRC2 | proline-rich nuclear receptor coactivator 2 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit |
| PPAN | peter pan homolog (Drosophila) |
| PPP1R8 | protein phosphatase 1, regulatory subunit 8 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PRR15L | proline rich 15-like |
| RANBP6 | RAN binding protein 6 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RBM4B | RNA binding motif protein 4B |
| RHOB | ras homolog family member B |
| RIOK2 | RIO kinase 2 |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| SCAF8 | SR-related CTD-associated factor 8 |
| SLBP | stem-loop binding protein |
| SLC38A2 | solute carrier family 38, member 2 |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) |
| SPATA2L | spermatogenesis associated 2-like |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 |
| STC2 | stanniocalcin 2 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa |
| TBK1 | TANK-binding kinase 1 |
| TGS1 | trimethylguanosine synthase 1 |
| THEM6 | thioesterase superfamily member 6 |
| TMEM186 | transmembrane protein 186 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A |
| TOB1 | transducer of ERBB2, 1 |
| TRIM13 | tripartite motif containing 13 |
| TRIM32 | tripartite motif containing 32 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USP21 | ubiquitin specific peptidase 21 |
| WDR5B | WD repeat domain 5B |
| XBP1 | X-box binding protein 1 |
| ZBED5 | zinc finger, BED-type containing 5 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZIC1 | Zic family member 1 |
| ZNF107 | zinc finger protein 107 |
| ZNF146 | zinc finger protein 146 |
| ZNF232 | zinc finger protein 232 |
| ZNF443 | zinc finger protein 443 |
| ZNF587 | zinc finger protein 587 |
| ZNF85 | zinc finger protein 85 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
