emetine-2145 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the emetine-2145 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM28 ADAM metallopeptidase domain 28
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AREG amphiregulin
ARHGAP25 Rho GTPase activating protein 25
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4C ADP-ribosylation factor-like 4C
ATAD2B ATPase family, AAA domain containing 2B
B9D2 B9 protein domain 2
BCL3 B-cell CLL/lymphoma 3
BIRC3 baculoviral IAP repeat containing 3
C17ORF53 chromosome 17 open reading frame 53
CCL20 chemokine (C-C motif) ligand 20
CCL4 chemokine (C-C motif) ligand 4
CD86 CD86 molecule
CDK12 cyclin-dependent kinase 12
CREM cAMP responsive element modulator
DNAH17 dynein, axonemal, heavy chain 17
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EGR2 early growth response 2
EGR3 early growth response 3
FCAR Fc fragment of IgA receptor
FILIP1L filamin A interacting protein 1-like
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
G0S2 G0/G1 switch 2
GADD45B growth arrest and DNA-damage-inducible, beta
GPR65 G protein-coupled receptor 65
HBEGF heparin-binding EGF-like growth factor
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BH histone cluster 1, H2bh
HIST1H2BJ histone cluster 1, H2bj
HIST1H4H histone cluster 1, H4h
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLX H2.0-like homeobox
HOXA9 homeobox A9
HRH1 histamine receptor H1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL10RA interleukin 10 receptor, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL24 interleukin 24
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
KLF10 Kruppel-like factor 10
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRCC1 lysine-rich coiled-coil 1
KYNU kynureninase
LAX1 lymphocyte transmembrane adaptor 1
MEF2C myocyte enhancer factor 2C
MTERF1 mitochondrial transcription termination factor 1
N4BP2L2 NEDD4 binding protein 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NLRP1 NLR family, pyrin domain containing 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
PCLO piccolo presynaptic cytomatrix protein
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLSCR1 phospholipid scramblase 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRDM1 PR domain containing 1, with ZNF domain
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTX3 pentraxin 3, long
RAB20 RAB20, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS2 regulator of G-protein signaling 2
RIN3 Ras and Rab interactor 3
RNF25 ring finger protein 25
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SNX11 sorting nexin 11
TGFBR3 transforming growth factor, beta receptor III
THAP10 THAP domain containing 10
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TRAF3IP2 TRAF3 interacting protein 2
TRAF3IP3 TRAF3 interacting protein 3
TXNIP thioredoxin interacting protein
UBAP1 ubiquitin associated protein 1
VNN1 vanin 1
ZNF222 zinc finger protein 222
ZNF606 zinc finger protein 606
ZNF671 zinc finger protein 671
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACVR2B activin A receptor, type IIB
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRA3 adhesion G protein-coupled receptor A3
ADM adrenomedullin
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASB13 ankyrin repeat and SOCS box containing 13
AXIN1 axin 1
C2CD2 C2 calcium-dependent domain containing 2
C5ORF30 chromosome 5 open reading frame 30
CALU calumenin
CBX6 chromobox homolog 6
CCNE1 cyclin E1
CCNE2 cyclin E2
CCNJ cyclin J
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEP295 centrosomal protein 295kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTH cystathionine gamma-lyase
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DEAF1 DEAF1 transcription factor
DHCR24 24-dehydrocholesterol reductase
DPY19L2P2 DPY19L2 pseudogene 2
DYM dymeclin
ENO2 enolase 2 (gamma, neuronal)
ERCC6L excision repair cross-complementation group 6-like
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM172A family with sequence similarity 172, member A
FAM20B family with sequence similarity 20, member B
FAM57A family with sequence similarity 57, member A
FAT1 FAT atypical cadherin 1
FOSL1 FOS-like antigen 1
GPR22 G protein-coupled receptor 22
GPR63 G protein-coupled receptor 63
HELLS helicase, lymphoid-specific
HLTF helicase-like transcription factor
HMGA2 high mobility group AT-hook 2
HSPA8 heat shock 70kDa protein 8
INSIG1 insulin induced gene 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNK5 potassium channel, two pore domain subfamily K, member 5
LAPTM4B lysosomal protein transmembrane 4 beta
LINC00597 long intergenic non-protein coding RNA 597
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MAN1C1 mannosidase, alpha, class 1C, member 1
MAT2A methionine adenosyltransferase II, alpha
MCM3AP-AS1 MCM3AP antisense RNA 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MSMO1 methylsterol monooxygenase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NPIPB3 nuclear pore complex interacting protein family, member B3
NTSR1 neurotensin receptor 1 (high affinity)
NUP210 nucleoporin 210kDa
OAT ornithine aminotransferase
PALB2 partner and localizer of BRCA2
PAQR4 progestin and adipoQ receptor family member IV
PARP1 poly (ADP-ribose) polymerase 1
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PBX3 pre-B-cell leukemia homeobox 3
PHGDH phosphoglycerate dehydrogenase
PIEZO1 piezo-type mechanosensitive ion channel component 1
PRKX protein kinase, X-linked
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSAT1 phosphoserine aminotransferase 1
RAD54L RAD54-like (S. cerevisiae)
SACS sacsin molecular chaperone
SDCCAG3 serologically defined colon cancer antigen 3
SFMBT1 Scm-like with four mbt domains 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLITRK5 SLIT and NTRK-like family, member 5
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNHG3 small nucleolar RNA host gene 3
SOX12 SRY (sex determining region Y)-box 12
SPON2 spondin 2, extracellular matrix protein
SPP1 secreted phosphoprotein 1
SQLE squalene epoxidase
STC2 stanniocalcin 2
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TMEM158 transmembrane protein 158 (gene/pseudogene)
TUBA3C tubulin, alpha 3c
TXLNG taxilin gamma
VANGL1 VANGL planar cell polarity protein 1
VLDLR very low density lipoprotein receptor
VSIG4 V-set and immunoglobulin domain containing 4
WRB tryptophan rich basic protein
WT1-AS WT1 antisense RNA
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF37BP zinc finger protein 37B, pseudogene