emetine-2801 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the emetine-2801 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ARID4A AT rich interactive domain 4A (RBP1-like)
ATF3 activating transcription factor 3
BCL3 B-cell CLL/lymphoma 3
BHLHE40 basic helix-loop-helix family, member e40
BHLHE41 basic helix-loop-helix family, member e41
BIRC3 baculoviral IAP repeat containing 3
BTN2A2 butyrophilin, subfamily 2, member A2
C8ORF4 chromosome 8 open reading frame 4
CCL2 chemokine (C-C motif) ligand 2
CCNL1 cyclin L1
CD83 CD83 molecule
CDKN2AIP CDKN2A interacting protein
CSF1 colony stimulating factor 1 (macrophage)
CTGF connective tissue growth factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DPY19L2P2 DPY19L2 pseudogene 2
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EFNA1 ephrin-A1
EGR1 early growth response 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENO3 enolase 3 (beta, muscle)
EPHA2 EPH receptor A2
FOS FBJ murine osteosarcoma viral oncogene homolog
FRMD4B FERM domain containing 4B
GADD45B growth arrest and DNA-damage-inducible, beta
H2AFJ H2A histone family, member J
HES1 hes family bHLH transcription factor 1
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H3H histone cluster 1, H3h
HIST1H4C histone cluster 1, H4c
HIST1H4H histone cluster 1, H4h
HIST2H2BE histone cluster 2, H2be
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL32 interleukin 32
IL6 interleukin 6
IRF1 interferon regulatory factor 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF10 Kruppel-like factor 10
KLF6 Kruppel-like factor 6
LDAH lipid droplet associated hydrolase
LIN7B lin-7 homolog B (C. elegans)
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K13 mitogen-activated protein kinase kinase kinase 13
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NKX3-1 NK3 homeobox 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
OPTN optineurin
PER1 period circadian clock 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTCH1 patched 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
SERTAD3 SERTA domain containing 3
SIRT4 sirtuin 4
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC16A6 solute carrier family 16, member 6
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SNCAIP synuclein, alpha interacting protein
SOX9 SRY (sex determining region Y)-box 9
SRCAP Snf2-related CREBBP activator protein
ST7L suppression of tumorigenicity 7 like
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ZFP36 ZFP36 ring finger protein
ZMYM5 zinc finger, MYM-type 5
ZNF34 zinc finger protein 34
ZNF571 zinc finger protein 571
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ABLIM3 actin binding LIM protein family, member 3
ADGRA3 adhesion G protein-coupled receptor A3
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD40 ankyrin repeat domain 40
BICD2 bicaudal D homolog 2 (Drosophila)
C5AR2 complement component 5a receptor 2
CAMK1 calcium/calmodulin-dependent protein kinase I
CCNE1 cyclin E1
CCNE2 cyclin E2
CCNG1 cyclin G1
CD302 CD302 molecule
CD81 CD81 molecule
CDC25A cell division cycle 25A
CDC50A cell division cycle 50 P4-ATPase accessory subunit A
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CENPQ centromere protein Q
CROT carnitine O-octanoyltransferase
DCAF13 DDB1 and CUL4 associated factor 13
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DPYSL2 dihydropyrimidinase-like 2
E2F6 E2F transcription factor 6
EGR3 early growth response 3
ERMP1 endoplasmic reticulum metallopeptidase 1
ERO1L ERO1-like (S. cerevisiae)
FAM114A1 family with sequence similarity 114, member A1
FAM172A family with sequence similarity 172, member A
FAM20B family with sequence similarity 20, member B
FAM3C family with sequence similarity 3, member C
FSD1 fibronectin type III and SPRY domain containing 1
FZD4 frizzled class receptor 4
GAMT guanidinoacetate N-methyltransferase
GJA1 gap junction protein, alpha 1, 43kDa
GNPDA1 glucosamine-6-phosphate deaminase 1
HECA headcase homolog (Drosophila)
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA8 heat shock 70kDa protein 8
INSIG1 insulin induced gene 1
KIAA0125 KIAA0125
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LOC257152 uncharacterized LOC257152
LOC390998 ribosomal protein L10 pseudogene
LPCAT1 lysophosphatidylcholine acyltransferase 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAN1A1 mannosidase, alpha, class 1A, member 1
MAT2A methionine adenosyltransferase II, alpha
MBTD1 mbt domain containing 1
MCM3AP-AS1 MCM3AP antisense RNA 1
MED9 mediator complex subunit 9
MEGF9 multiple EGF-like-domains 9
METTL2B methyltransferase like 2B
MGC12488
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NPFFR1 neuropeptide FF receptor 1
NPY1R neuropeptide Y receptor Y1
PARD6A par-6 family cell polarity regulator alpha
PCDHB3 protocadherin beta 3
PDZD8 PDZ domain containing 8
PLA2G12A phospholipase A2, group XIIA
PPP1R26 protein phosphatase 1, regulatory subunit 26
PRKX protein kinase, X-linked
RABAC1 Rab acceptor 1 (prenylated)
REPS2 RALBP1 associated Eps domain containing 2
RNF38 ring finger protein 38
RNF44 ring finger protein 44
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS14P3 ribosomal protein S14 pseudogene 3
SACS sacsin molecular chaperone
SERINC5 serine incorporator 5
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC38A1 solute carrier family 38, member 1
SLC38A2 solute carrier family 38, member 2
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNHG3 small nucleolar RNA host gene 3
SNORA21 small nucleolar RNA, H/ACA box 21
SNX6 sorting nexin 6
SOWAHC sosondowah ankyrin repeat domain family member C
SRD5A3 steroid 5 alpha-reductase 3
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
TFDP1 transcription factor Dp-1
TMEM109 transmembrane protein 109
TMEM123 transmembrane protein 123
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
UBL3 ubiquitin-like 3
UNKL unkempt family zinc finger-like
WRB tryptophan rich basic protein
ZBTB22 zinc finger and BTB domain containing 22
ZMAT3 zinc finger, matrin-type 3