| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the emetine-4243 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADM | adrenomedullin |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATF3 | activating transcription factor 3 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CDKN2AIP | CDKN2A interacting protein |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLK4 | CDC-like kinase 4 |
| COL4A6 | collagen, type IV, alpha 6 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DLX2 | distal-less homeobox 2 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNMBP | dynamin binding protein |
| DUSP1 | dual specificity phosphatase 1 |
| EDN1 | endothelin 1 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| FRMD4B | FERM domain containing 4B |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GATA3 | GATA binding protein 3 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPR87 | G protein-coupled receptor 87 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3H | histone cluster 1, H3h |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4H | histone cluster 1, H4h |
| HIST2H2BE | histone cluster 2, H2be |
| HIST3H2A | histone cluster 3, H2a |
| HOXA1 | homeobox A1 |
| ICAM1 | intercellular adhesion molecule 1 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL1A | interleukin 1, alpha |
| IL24 | interleukin 24 |
| IL6 | interleukin 6 |
| ING3 | inhibitor of growth family, member 3 |
| IRF1 | interferon regulatory factor 1 |
| JUN | jun proto-oncogene |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KLF2 | Kruppel-like factor 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF6 | Kruppel-like factor 6 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MT1F | metallothionein 1F |
| MT1M | metallothionein 1M |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PER1 | period circadian clock 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PTHLH | parathyroid hormone-like hormone |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RND1 | Rho family GTPase 1 |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 |
| RUNX1 | runt-related transcription factor 1 |
| SAFB | scaffold attachment factor B |
| SFPQ | splicing factor proline/glutamine-rich |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| ST7L | suppression of tumorigenicity 7 like |
| STC2 | stanniocalcin 2 |
| STX1A | syntaxin 1A (brain) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TP53 | tumor protein p53 |
| TUFT1 | tuftelin 1 |
| TXNIP | thioredoxin interacting protein |
| ZNF16 | zinc finger protein 16 |
| ZNF235 | zinc finger protein 235 |
| ZNF274 | zinc finger protein 274 |
| ZNF350 | zinc finger protein 350 |
| ZNF442 | zinc finger protein 442 |
| ZNF571 | zinc finger protein 571 |
| ZNF606 | zinc finger protein 606 |
| ZNF671 | zinc finger protein 671 |
| Symbol | Name |
|---|---|
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| AXIN1 | axin 1 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 |
| BCL7A | B-cell CLL/lymphoma 7A |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CD302 | CD302 molecule |
| CD68 | CD68 molecule |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A |
| CDON | cell adhesion associated, oncogene regulated |
| CERK | ceramide kinase |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CRABP2 | cellular retinoic acid binding protein 2 |
| DMTN | dematin actin binding protein |
| DSPP | dentin sialophosphoprotein |
| EFNA3 | ephrin-A3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM172A | family with sequence similarity 172, member A |
| FAM20B | family with sequence similarity 20, member B |
| FBXO2 | F-box protein 2 |
| FST | follistatin |
| FZD4 | frizzled class receptor 4 |
| FZD8 | frizzled class receptor 8 |
| GBX2 | gastrulation brain homeobox 2 |
| GRM4 | glutamate receptor, metabotropic 4 |
| HDAC4 | histone deacetylase 4 |
| HELLS | helicase, lymphoid-specific |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HSPA1A | heat shock 70kDa protein 1A |
| IL36RN | interleukin 36 receptor antagonist |
| INHBB | inhibin, beta B |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KIAA1456 | KIAA1456 |
| KIAA1462 | KIAA1462 |
| KLF13 | Kruppel-like factor 13 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC100127972 | uncharacterized LOC100127972 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MBTD1 | mbt domain containing 1 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MSX1 | msh homeobox 1 |
| MTSS1L | metastasis suppressor 1-like |
| MYO15A | myosin XVA |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUBPL | nucleotide binding protein-like |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PDZD8 | PDZ domain containing 8 |
| PLBD1 | phospholipase B domain containing 1 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PRKX | protein kinase, X-linked |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTGFR | prostaglandin F receptor (FP) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RGCC | regulator of cell cycle |
| RGS19 | regulator of G-protein signaling 19 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUFY2 | RUN and FYVE domain containing 2 |
| SERINC5 | serine incorporator 5 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNHG3 | small nucleolar RNA host gene 3 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| STBD1 | starch binding domain 1 |
| STIM1 | stromal interaction molecule 1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TMEM121 | transmembrane protein 121 |
| TMEM212 | transmembrane protein 212 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| UNC119B | unc-119 homolog B (C. elegans) |
| UNKL | unkempt family zinc finger-like |
| VGF | VGF nerve growth factor inducible |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZMAT3 | zinc finger, matrin-type 3 |