emetine-hcl Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

658 genes differentially expressed following the emetine-hcl small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RBKS ribokinase 7.32073
DDB2 damage-specific DNA binding protein 2, 48kDa 6.12269
H2AC6 H2A clustered histone 6 6.00363
TOGARAM1 TOG array regulator of axonemal microtubules 1 5.93703
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 5.89944
SOCS2 suppressor of cytokine signaling 2 5.84878
CENPE centromere protein E, 312kDa 5.72724
THADA thyroid adenoma associated 5.711
ZNF79 zinc finger protein 79 5.66719
METTL18 methyltransferase like 18 5.66717
PRKCH protein kinase C, eta 5.6086
TRIP11 thyroid hormone receptor interactor 11 5.5591
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 5.54193
NGDN neuroguidin, EIF4E binding protein 5.53684
PCF11 PCF11 cleavage and polyadenylation factor subunit 5.47296
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 5.45494
SNW1 SNW domain containing 1 5.40456
H2BC11 H2B clustered histone 11 5.37843
H2BC9 H2B clustered histone 9 5.29669
CDKL3 cyclin-dependent kinase-like 3 5.28753
TGFB2 transforming growth factor, beta 2 5.24563
JUN jun proto-oncogene 5.24351
IFT74 intraflagellar transport 74 5.13646
HES1 hes family bHLH transcription factor 1 5.09242
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 5.04047
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 5.01884
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 4.95204
ANKRD12 ankyrin repeat domain 12 4.94253
BIRC2 baculoviral IAP repeat containing 2 4.93459
ZNF140 zinc finger protein 140 4.89541
H2BC3 H2B clustered histone 3 4.88016
INTS12 integrator complex subunit 12 4.87329
THUMPD2 THUMP domain containing 2 4.81554
GADD45B growth arrest and DNA-damage-inducible, beta 4.80661
ATAD2B ATPase family, AAA domain containing 2B 4.79229
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 4.71795
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 4.71675
CLK4 CDC-like kinase 4 4.65061
SIRT4 sirtuin 4 4.61457
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 4.61379
PRCP prolylcarboxypeptidase (angiotensinase C) 4.58862
C1ORF105 chromosome 1 open reading frame 105 4.5849
TPR translocated promoter region, nuclear basket protein 4.57742
POLI polymerase (DNA directed) iota 4.57736
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 4.57502
ICOS inducible T-cell co-stimulator 4.56284
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 4.5521
TRMO tRNA methyltransferase O 4.53926
DNM3 dynamin 3 4.5322
H2BC5 H2B clustered histone 5 4.52215
XPA xeroderma pigmentosum, complementation group A 4.52099
H2BC17 H2B clustered histone 17 4.50493
WDR33 WD repeat domain 33 4.50379
TMEM80 transmembrane protein 80 4.48769
CENPF centromere protein F, 350/400kDa 4.48178
NME7 NME/NM23 family member 7 4.4663
DAXX death-domain associated protein 4.44805
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 4.43638
KIF18A kinesin family member 18A 4.4356
LYST lysosomal trafficking regulator 4.4227
ARID5B AT rich interactive domain 5B (MRF1-like) 4.41539
CCL15 chemokine (C-C motif) ligand 15 4.39759
ELP4 elongator acetyltransferase complex subunit 4 4.39372
DUSP14 dual specificity phosphatase 14 4.35259
PHF3 PHD finger protein 3 4.34181
OCA2 oculocutaneous albinism II 4.33776
SSX3 synovial sarcoma, X breakpoint 3 4.31611
SRCAP Snf2-related CREBBP activator protein 4.3142
RNF25 ring finger protein 25 4.30892
ATF7IP activating transcription factor 7 interacting protein 4.27031
IL23A interleukin 23, alpha subunit p19 4.26794
ZNHIT2 zinc finger, HIT-type containing 2 4.26542
HOXC13 homeobox C13 4.26088
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 4.25271
HMMR hyaluronan-mediated motility receptor (RHAMM) 4.25059
C18ORF25 chromosome 18 open reading frame 25 4.24688
MTRF1 mitochondrial translational release factor 1 4.24641
SOX4 SRY (sex determining region Y)-box 4 4.23989
PHF21A PHD finger protein 21A 4.23919
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 4.22766
KMT5B lysine methyltransferase 5B 4.22201
ERBB4 erb-b2 receptor tyrosine kinase 4 4.21423
ARID4B AT rich interactive domain 4B (RBP1-like) 4.213
HCFC2 host cell factor C2 4.2009
PSPC1 paraspeckle component 1 4.18346
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 4.18144
RIGI RNA sensor RIG-I 4.17957
MLH1 mutL homolog 1 4.17787
ST7L suppression of tumorigenicity 7 like 4.17241
FILIP1L filamin A interacting protein 1-like 4.16616
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 4.15604
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 4.14191
THOC1 THO complex 1 4.13468
CCDC7 coiled-coil domain containing 7 4.13019
CALCR calcitonin receptor 4.12019
RIOK2 RIO kinase 2 4.11305
BAZ1A bromodomain adjacent to zinc finger domain, 1A 4.10624
RPP38 ribonuclease P/MRP 38kDa subunit 4.10473
PEX12 peroxisomal biogenesis factor 12 4.09364
NPAT nuclear protein, ataxia-telangiectasia locus 4.06851
H1-2 H1.2 linker histone, cluster member 4.06651
IL21 interleukin 21 4.0627
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene 4.05936
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 4.058
TBC1D31 TBC1 domain family, member 31 4.05103
OBI1 ORC ubiquitin ligase 1 4.04027
EDN1 endothelin 1 4.03901
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4.02325
REXO5 RNA exonuclease 5 4.02308
IFT88 intraflagellar transport 88 4.01643
RNF146 ring finger protein 146 4.00592
SMC6 structural maintenance of chromosomes 6 4.0024
SPA17 sperm autoantigenic protein 17 3.98953
DERA deoxyribose-phosphate aldolase (putative) 3.9557
GIN1 gypsy retrotransposon integrase 1 3.94622
MYNN myoneurin 3.93426
SYCP1 synaptonemal complex protein 1 3.93152
H2AC14 H2A clustered histone 14 3.92412
VCX2 variable charge, X-linked 2 3.924
BTBD3 BTB (POZ) domain containing 3 3.90734
ODF1 outer dense fiber of sperm tails 1 3.90675
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 3.90258
SIK3 SIK family kinase 3 3.89723
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 3.89583
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.89356
ZBTB25 zinc finger and BTB domain containing 25 3.87413
TNPO1 transportin 1 3.87027
RSRC2 arginine/serine-rich coiled-coil 2 3.86597
PFDN2 prefoldin subunit 2 3.86049
PPIA peptidylprolyl isomerase A (cyclophilin A) 3.85943
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 3.85595
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 3.83889
H2AC13 H2A clustered histone 13 3.83631
ADNP2 ADNP homeobox 2 3.83349
SPATA5L1 spermatogenesis associated 5-like 1 3.82853
SMCP sperm mitochondria-associated cysteine-rich protein 3.8216
PTCD2 pentatricopeptide repeat domain 2 3.81815
ZNF45 zinc finger protein 45 3.81478
MRFAP1L1 Morf4 family associated protein 1-like 1 3.80873
AOPEP aminopeptidase O (putative) 3.80313
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) 3.79781
ZNF510 zinc finger protein 510 3.79676
ZC2HC1C zinc finger, C2HC-type containing 1C 3.79523
INTS7 integrator complex subunit 7 3.79193
C1ORF50 chromosome 1 open reading frame 50 3.78498
SLC16A6 solute carrier family 16, member 6 3.7803
IFNB1 interferon, beta 1, fibroblast 3.77186
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 3.76721
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 3.76597
TKTL1 transketolase-like 1 3.76458
IRAK4 interleukin-1 receptor-associated kinase 4 3.75737
ZFPM2 zinc finger protein, FOG family member 2 3.74423
DBP D site of albumin promoter (albumin D-box) binding protein 3.72933
PTBP2 polypyrimidine tract binding protein 2 3.72616
EXOC7 exocyst complex component 7 3.70798
DGKI diacylglycerol kinase, iota 3.70717
MCTP1 multiple C2 domains, transmembrane 1 3.70232
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.69672
RASAL2 RAS protein activator like 2 3.69193
PAN2 PAN2 poly(A) specific ribonuclease subunit 3.68825
PCLO piccolo presynaptic cytomatrix protein 3.68124
ABITRAM actin binding transcription modulator 3.67785
ZNF227 zinc finger protein 227 3.66437
CEP192 centrosomal protein 192kDa 3.66354
CCRL2 chemokine (C-C motif) receptor-like 2 3.65995
UIMC1 ubiquitin interaction motif containing 1 3.6596
C21ORF91 chromosome 21 open reading frame 91 3.64524
HJURP Holliday junction recognition protein 3.64233
MTERF1 mitochondrial transcription termination factor 1 3.64125
ERICH1 glutamate-rich 1 3.62936
NOVA1 neuro-oncological ventral antigen 1 3.62523
WASHC3 WASH complex subunit 3 3.62474
TDRD7 tudor domain containing 7 3.62005
IK IK cytokine, down-regulator of HLA II 3.61888
PRDM4 PR domain containing 4 3.61413
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.60991
PALB2 partner and localizer of BRCA2 3.60763
SART3 squamous cell carcinoma antigen recognized by T cells 3 3.60576
GSPT2 G1 to S phase transition 2 3.60329
C11ORF71 chromosome 11 open reading frame 71 3.59906
TTLL5 tubulin tyrosine ligase-like family member 5 3.59519
SLCO5A1 solute carrier organic anion transporter family, member 5A1 3.5915
COA7 cytochrome c oxidase assembly factor 7 (putative) 3.59126
ABRAXAS2 abraxas 2, BRISC complex subunit 3.58885
MRM3 mitochondrial rRNA methyltransferase 3 3.57927
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 3.57863
YTHDC1 YTH domain containing 1 3.57194
LTN1 listerin E3 ubiquitin protein ligase 1 3.56987
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 3.56707
SIRPG signal-regulatory protein gamma 3.55454
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 3.55072
USP15 ubiquitin specific peptidase 15 3.55023
ZNF804A zinc finger protein 804A 3.54881
ZSCAN32 zinc finger and SCAN domain containing 32 3.54752
PRPF38B pre-mRNA processing factor 38B 3.54167
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 3.54117
SMC3 structural maintenance of chromosomes 3 3.53671
TGFB3 transforming growth factor, beta 3 3.52631
IL3RA interleukin 3 receptor, alpha (low affinity) 3.52334
BCOR BCL6 corepressor 3.52027
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 3.51931
BNC2 basonuclin 2 3.51026
RSF1 remodeling and spacing factor 1 3.50942
IFT81 intraflagellar transport 81 3.49669
TSGA10 testis specific, 10 3.48954
PDHX pyruvate dehydrogenase complex, component X 3.4864
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 3.47858
KIAA0586 KIAA0586 3.47833
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 3.47725
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 3.47692
ZNF85 zinc finger protein 85 3.47343
ERI2 ERI1 exoribonuclease family member 2 3.47328
UTP25 UTP25 small subunit processome component 3.47283
WBP4 WW domain binding protein 4 3.46476
ZNF821 zinc finger protein 821 3.46328
C10ORF88 chromosome 10 open reading frame 88 3.46256
ZNF200 zinc finger protein 200 3.45845
LNPEP leucyl/cystinyl aminopeptidase 3.4581
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 3.45044
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 3.4485
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 3.43492
SCN2A sodium channel, voltage gated, type II alpha subunit 3.43451
TRIM23 tripartite motif containing 23 3.42691
XPO1 exportin 1 3.4209
ZMYM4 zinc finger, MYM-type 4 3.41471
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 3.41379
DOP1A DOP1 leucine zipper like protein A 3.41147
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) 3.40805
GPN2 GPN-loop GTPase 2 3.40788
CEP135 centrosomal protein 135kDa 3.39823
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 3.39357
KLF10 Kruppel-like factor 10 3.38903
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 3.38817
LRRC17 leucine rich repeat containing 17 3.38784
CRY1 cryptochrome circadian clock 1 3.38597
WNT4 wingless-type MMTV integration site family, member 4 3.38581
EDC3 enhancer of mRNA decapping 3 3.38513
PLEKHA8P1 pleckstrin homology domain containing, family A member 8 pseudogene 1 3.37813
RABEP1 rabaptin, RAB GTPase binding effector protein 1 3.37299
C12ORF4 chromosome 12 open reading frame 4 3.36449
GTPBP4 GTP binding protein 4 3.36386
BMPR1B bone morphogenetic protein receptor, type IB 3.36084
CCDC90B coiled-coil domain containing 90B 3.3591
ZNF451 zinc finger protein 451 3.35646
CDADC1 cytidine and dCMP deaminase domain containing 1 3.35323
EDA2R ectodysplasin A2 receptor 3.34919
GSTZ1 glutathione S-transferase zeta 1 3.34859
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 3.34847
EPB41L2 erythrocyte membrane protein band 4.1-like 2 3.34636
NPAS3 neuronal PAS domain protein 3 3.34456
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 3.33766
KDM5B lysine (K)-specific demethylase 5B 3.32824
APOLD1 apolipoprotein L domain containing 1 3.32736
ZNF606 zinc finger protein 606 3.32709
NBR1 neighbor of BRCA1 gene 1 3.32691
EMC9 ER membrane protein complex subunit 9 3.32337
ZNF7 zinc finger protein 7 3.32173
UVRAG UV radiation resistance associated 3.32141
NFX1 nuclear transcription factor, X-box binding 1 3.32064
MED13L mediator complex subunit 13-like 3.32036
CEP76 centrosomal protein 76kDa 3.31974
NSUN3 NOP2/Sun domain family, member 3 3.31912
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 3.31796
TTC12 tetratricopeptide repeat domain 12 3.30843
MED1 mediator complex subunit 1 3.30368
STARD13 StAR-related lipid transfer (START) domain containing 13 3.30348
MID1 midline 1 3.29897
TNF tumor necrosis factor 3.29574
CDK7 cyclin-dependent kinase 7 3.29564
ZNF571 zinc finger protein 571 3.2927
APH1B APH1B gamma secretase subunit 3.2926
CD83 CD83 molecule 3.29218
DDIT3 DNA-damage-inducible transcript 3 3.29089
PARP11 poly (ADP-ribose) polymerase family, member 11 3.2902
RASA1 RAS p21 protein activator (GTPase activating protein) 1 3.28712
CDK17 cyclin-dependent kinase 17 3.28528
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 3.28276
GPR52 G protein-coupled receptor 52 3.2791
KRCC1 lysine-rich coiled-coil 1 3.27577
TASOR transcription activation suppressor 3.27255
CEP290 centrosomal protein 290kDa 3.26907
ACKR3 atypical chemokine receptor 3 3.26603
RB1CC1 RB1-inducible coiled-coil 1 3.26374
GIGYF2 GRB10 interacting GYF protein 2 3.2623
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 3.26176
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 3.25725
AKAP4 A kinase (PRKA) anchor protein 4 3.25712
H2BC21 H2B clustered histone 21 3.2558
MTMR6 myotubularin related protein 6 3.25557
CD3G CD3g molecule, gamma (CD3-TCR complex) 3.25176
YJU2B YJU2 splicing factor homolog B 3.24418
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 3.23626
CFLAR CASP8 and FADD-like apoptosis regulator 3.23531
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 3.23318
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 3.23283
BEX3 brain expressed X-linked 3 3.23
CRNKL1 crooked neck pre-mRNA splicing factor 1 3.22608
H2AC8 H2A clustered histone 8 3.22592
CDC73 cell division cycle 73 3.22275
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 3.21977
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 3.21646
MED17 mediator complex subunit 17 3.21605
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 3.2158
ICE2 interactor of little elongation complex ELL subunit 2 3.21125
MTERF4 mitochondrial transcription termination factor 4 3.20526
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 3.20276
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 3.2024
CNTRL centriolin 3.19807
SOX30 SRY (sex determining region Y)-box 30 3.19295
ZFR zinc finger RNA binding protein 3.19284
NKAPD1 NKAP domain containing 1 3.19254
EMCN endomucin 3.18914
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 3.187
TUFT1 tuftelin 1 3.18646
CHM choroideremia (Rab escort protein 1) 3.18453
NCAPG non-SMC condensin I complex, subunit G 3.18432
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 3.18349
CLDN1 claudin 1 3.17675
H2BC12 H2B clustered histone 12 3.17336
TRAPPC10 trafficking protein particle complex 10 3.16934
TMEM187 transmembrane protein 187 3.16666
SFRP4 secreted frizzled-related protein 4 3.16217
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene 3.15991
CHTOP chromatin target of PRMT1 3.15866
ZNF442 zinc finger protein 442 3.15603
TSG101 tumor susceptibility 101 3.15404
RPL9 ribosomal protein L9 3.1522
ZC3H11A zinc finger CCCH-type containing 11A 3.1448
CDK13 cyclin-dependent kinase 13 3.14458
NUP88 nucleoporin 88kDa 3.14328
NR1D2 nuclear receptor subfamily 1, group D, member 2 3.1418
STK38L serine/threonine kinase 38 like 3.13813
ZNF33B zinc finger protein 33B 3.13787
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 3.13579
DSC2 desmocollin 2 3.12158
SRPK2 SRSF protein kinase 2 3.11921
SMC4 structural maintenance of chromosomes 4 3.11814
ZNF134 zinc finger protein 134 3.11766
PIBF1 progesterone immunomodulatory binding factor 1 3.1145
PEX16 peroxisomal biogenesis factor 16 3.11403
OARD1 O-acyl-ADP-ribose deacylase 1 3.11382
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 3.11212
CADM1 cell adhesion molecule 1 3.11052
CLEC1A C-type lectin domain family 1, member A 3.10856
ZNF557 zinc finger protein 557 3.10807
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 3.10588
CEP162 centrosomal protein 162kDa 3.10391
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 3.10301
RMI1 RecQ mediated genome instability 1 3.09557
CKS2 CDC28 protein kinase regulatory subunit 2 3.09479
NEK11 NIMA-related kinase 11 3.09033
RPS24 ribosomal protein S24 3.08952
THAP1 THAP domain containing, apoptosis associated protein 1 3.08786
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 3.08614
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 3.08579
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 3.08547
TTC30A tetratricopeptide repeat domain 30A 3.08385
LCMT2 leucine carboxyl methyltransferase 2 3.0826
ZNF268 zinc finger protein 268 3.08171
BMP4 bone morphogenetic protein 4 3.07937
S1PR1 sphingosine-1-phosphate receptor 1 3.07539
SPEN spen family transcriptional repressor 3.07149
NCAPD2 non-SMC condensin I complex, subunit D2 3.06937
CATSPERG catsper channel auxiliary subunit gamma 3.06936
CCDC170 coiled-coil domain containing 170 3.06916
MNAT1 MNAT CDK-activating kinase assembly factor 1 3.06781
PALS1 protein associated with LIN7 1, MAGUK p55 family member 3.06628
OSR2 odd-skipped related transciption factor 2 3.06095
GEM GTP binding protein overexpressed in skeletal muscle 3.05969
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 3.05665
STYXL1 serine/threonine/tyrosine interacting-like 1 3.05528
CDK6 cyclin-dependent kinase 6 3.05162
JMJD1C jumonji domain containing 1C 3.05081
LINS1 lines homolog 1 3.04696
AMOTL2 angiomotin like 2 3.0454
RNMT RNA (guanine-7-) methyltransferase 3.04428
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 3.04195
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 3.03737
NIT1 nitrilase 1 3.03606
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 3.03474
TTC4 tetratricopeptide repeat domain 4 3.02761
BATF basic leucine zipper transcription factor, ATF-like 3.02529
LTB lymphotoxin beta (TNF superfamily, member 3) 3.02461
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 3.02389
GDAP1 ganglioside induced differentiation associated protein 1 3.0237
AKAP3 A kinase (PRKA) anchor protein 3 3.02286
FLRT2 fibronectin leucine rich transmembrane protein 2 3.01607
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 3.01553
TSNAXIP1 translin-associated factor X interacting protein 1 3.01444
HINFP histone H4 transcription factor 3.01388
INTS6 integrator complex subunit 6 3.01333
CHD1 chromodomain helicase DNA binding protein 1 3.01159
GFI1 growth factor independent 1 transcription repressor 3.01096
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 3.00832
MFAP3 microfibrillar-associated protein 3 3.00473
TJP1 tight junction protein 1 3.00439
EYA4 EYA transcriptional coactivator and phosphatase 4 3.00433
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 3.00227

decreased expression

Symbol Name Standardized Value
CRTAP cartilage associated protein -6.17229
CALU calumenin -6.00063
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -5.74585
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -5.72864
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -5.67747
MAT2A methionine adenosyltransferase II, alpha -5.54156
TMEM109 transmembrane protein 109 -5.36101
NAGA N-acetylgalactosaminidase, alpha- -5.12547
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -5.09315
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 -5.05438
CSNK1E casein kinase 1, epsilon -5.04106
CTSB cathepsin B -4.92674
FCHSD2 FCH and double SH3 domains 2 -4.86562
PHGDH phosphoglycerate dehydrogenase -4.82758
NUP43 nucleoporin 43kDa -4.82128
MLEC malectin -4.81871
C2CD2 C2 calcium-dependent domain containing 2 -4.74995
HSPA8 heat shock 70kDa protein 8 -4.73684
IL13RA1 interleukin 13 receptor, alpha 1 -4.72609
MPST mercaptopyruvate sulfurtransferase -4.71787
NUCB2 nucleobindin 2 -4.65102
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -4.64766
MAP3K6 mitogen-activated protein kinase kinase kinase 6 -4.58033
MBOAT2 membrane bound O-acyltransferase domain containing 2 -4.56228
INSIG1 insulin induced gene 1 -4.56052
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -4.55083
PACS2 phosphofurin acidic cluster sorting protein 2 -4.517
UNC5B unc-5 homolog B (C. elegans) -4.5051
XPOT exportin, tRNA -4.47341
LOXL1 lysyl oxidase-like 1 -4.4123
FAM20B family with sequence similarity 20, member B -4.34166
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 -4.32245
CARM1 coactivator-associated arginine methyltransferase 1 -4.259
RAB11A RAB11A, member RAS oncogene family -4.2451
ANXA11 annexin A11 -4.24099
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -4.23994
GPD1L glycerol-3-phosphate dehydrogenase 1-like -4.23416
FKBP9 FK506 binding protein 9, 63 kDa -4.22317
ICMT isoprenylcysteine carboxyl methyltransferase -4.19908
SH2D2A SH2 domain containing 2A -4.19535
DNPEP aspartyl aminopeptidase -4.17722
EPN3 epsin 3 -4.17221
MCM5 minichromosome maintenance complex component 5 -4.17157
NUCB1 nucleobindin 1 -4.15002
ZDHHC18 zinc finger, DHHC-type containing 18 -4.12854
SCARB1 scavenger receptor class B, member 1 -4.10861
PYCR1 pyrroline-5-carboxylate reductase 1 -4.1082
TEAD3 TEA domain family member 3 -4.09264
GM2A GM2 ganglioside activator -4.08313
C1ORF174 chromosome 1 open reading frame 174 -4.04766
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha -4.0434
DVL3 dishevelled segment polarity protein 3 -4.04322
PDIA4 protein disulfide isomerase family A, member 4 -4.0313
CCNI cyclin I -4.03111
GSR glutathione reductase -4.02604
SNX1 sorting nexin 1 -4.02253
NCK2 NCK adaptor protein 2 -4.01768
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 -4.00707
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -3.99623
GTPBP3 GTP binding protein 3 (mitochondrial) -3.98231
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -3.97694
CYB5R3 cytochrome b5 reductase 3 -3.97152
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -3.96949
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 -3.96075
ENTREP3 endosomal transmembrane epsin interactor 3 -3.94464
ELAC2 elaC ribonuclease Z 2 -3.93881
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase -3.89945
ALG3 ALG3, alpha-1,3- mannosyltransferase -3.85507
ADIRF adipogenesis regulatory factor -3.85037
LAMP1 lysosomal-associated membrane protein 1 -3.82757
HSPA1A heat shock 70kDa protein 1A -3.81353
TMEM147 transmembrane protein 147 -3.80986
CIB2 calcium and integrin binding family member 2 -3.80429
PDIA3 protein disulfide isomerase family A, member 3 -3.80283
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -3.78074
TMEM164 transmembrane protein 164 -3.77931
CBS cystathionine-beta-synthase -3.77803
GRM5 glutamate receptor, metabotropic 5 -3.77799
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -3.77151
RPA1 replication protein A1, 70kDa -3.76609
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -3.75257
SCD stearoyl-CoA desaturase (delta-9-desaturase) -3.74608
RIPPLY3 ripply transcriptional repressor 3 -3.73579
RUSC1 RUN and SH3 domain containing 1 -3.73323
PTPRU protein tyrosine phosphatase, receptor type, U -3.7331
TMC7 transmembrane channel-like 7 -3.72111
APLP2 amyloid beta (A4) precursor-like protein 2 -3.71022
NQO2 NAD(P)H dehydrogenase, quinone 2 -3.7096
CCPG1 cell cycle progression 1 -3.70886
MPZL1 myelin protein zero-like 1 -3.70351
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -3.70007
P4HB prolyl 4-hydroxylase, beta polypeptide -3.6989
ANKH ANKH inorganic pyrophosphate transport regulator -3.69799
MCM3 minichromosome maintenance complex component 3 -3.69277
PPARD peroxisome proliferator-activated receptor delta -3.68766
STS steroid sulfatase (microsomal), isozyme S -3.67971
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -3.67073
MFGE8 milk fat globule-EGF factor 8 protein -3.66776
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -3.66652
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -3.66439
MOCOS molybdenum cofactor sulfurase -3.66432
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -3.65429
COPG1 coatomer protein complex, subunit gamma 1 -3.65249
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) -3.64365
TPBG trophoblast glycoprotein -3.64191
IL26 interleukin 26 -3.63747
OGG1 8-oxoguanine DNA glycosylase -3.63382
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -3.63324
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -3.60009
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -3.59637
SNHG3 small nucleolar RNA host gene 3 -3.59483
DUSP7 dual specificity phosphatase 7 -3.58737
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -3.5786
CASP10 caspase 10, apoptosis-related cysteine peptidase -3.57593
CLCC1 chloride channel CLIC-like 1 -3.57147
EFS embryonal Fyn-associated substrate -3.56973
EMP2 epithelial membrane protein 2 -3.56904
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 -3.56481
MBOAT7 membrane bound O-acyltransferase domain containing 7 -3.56121
PSAT1 phosphoserine aminotransferase 1 -3.54979
AOC4P amine oxidase, copper containing 4, pseudogene -3.54773
UNG uracil-DNA glycosylase -3.54688
SEC13 SEC13 homolog (S. cerevisiae) -3.54436
CHAF1B chromatin assembly factor 1, subunit B (p60) -3.52084
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -3.50913
PDIA6 protein disulfide isomerase family A, member 6 -3.50805
PDLIM1 PDZ and LIM domain 1 -3.50566
CTSZ cathepsin Z -3.49878
COL9A1 collagen, type IX, alpha 1 -3.49506
MCUB mitochondrial calcium uniporter dominant negative subunit beta -3.49335
TSPYL1 TSPY-like 1 -3.49062
FGFR1 fibroblast growth factor receptor 1 -3.48721
NPTX2 neuronal pentraxin II -3.47154
YIPF3 Yip1 domain family, member 3 -3.47126
ECHDC2 enoyl CoA hydratase domain containing 2 -3.47042
ITPK1 inositol-tetrakisphosphate 1-kinase -3.47016
MLXIP MLX interacting protein -3.46396
MPRIP myosin phosphatase Rho interacting protein -3.46358
SAR1A secretion associated, Ras related GTPase 1A -3.46257
CRELD1 cysteine-rich with EGF-like domains 1 -3.45661
METAP1 methionyl aminopeptidase 1 -3.44937
CALR calreticulin -3.44111
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -3.4307
SORBS3 sorbin and SH3 domain containing 3 -3.42882
SLC19A1 solute carrier family 19 (folate transporter), member 1 -3.42081
FHOD1 formin homology 2 domain containing 1 -3.419
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -3.40629
MGLL monoglyceride lipase -3.40339
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -3.40205
TM9SF2 transmembrane 9 superfamily member 2 -3.39608
TRIB3 tribbles pseudokinase 3 -3.39421
MYD88 myeloid differentiation primary response 88 -3.39118
TRIOBP TRIO and F-actin binding protein -3.37904
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -3.37902
NFE2L1 nuclear factor, erythroid 2-like 1 -3.37873
ASIC1 acid sensing (proton gated) ion channel 1 -3.36601
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F -3.36483
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -3.35948
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -3.35823
FTO fat mass and obesity associated -3.35618
SPINT1 serine peptidase inhibitor, Kunitz type 1 -3.3514
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -3.34998
EML2 echinoderm microtubule associated protein like 2 -3.34465
MED9 mediator complex subunit 9 -3.33641
PDIA5 protein disulfide isomerase family A, member 5 -3.32847
BCR breakpoint cluster region -3.32474
PDZD8 PDZ domain containing 8 -3.31993
CDCP1 CUB domain containing protein 1 -3.30657
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -3.29254
TECR trans-2,3-enoyl-CoA reductase -3.29031
H2AZ2 H2A.Z variant histone 2 -3.28942
CTDNEP1 CTD nuclear envelope phosphatase 1 -3.28816
ILVBL ilvB (bacterial acetolactate synthase)-like -3.28793
TADA3 transcriptional adaptor 3 -3.27952
TMEM214 transmembrane protein 214 -3.27829
TUSC3 tumor suppressor candidate 3 -3.27601
MAPK3 mitogen-activated protein kinase 3 -3.26403
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -3.25702
PLPPR2 phospholipid phosphatase related 2 -3.25662
CHPF2 chondroitin polymerizing factor 2 -3.25564
AGMAT agmatine ureohydrolase (agmatinase) -3.25151
GPR153 G protein-coupled receptor 153 -3.24085
STK24 serine/threonine kinase 24 -3.23923
PEBP1 phosphatidylethanolamine binding protein 1 -3.23296
ATP2A3 ATPase, Ca++ transporting, ubiquitous -3.23093
ATXN2L ataxin 2-like -3.22637
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -3.22413
CC2D1A coiled-coil and C2 domain containing 1A -3.22386
TSEN34 TSEN34 tRNA splicing endonuclease subunit -3.21989
BACE2 beta-site APP-cleaving enzyme 2 -3.21568
SDC2 syndecan 2 -3.21302
PRKX protein kinase, X-linked -3.21234
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -3.20541
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -3.20155
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -3.19334
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -3.19197
TMED2 transmembrane emp24 domain trafficking protein 2 -3.18998
ZNF358 zinc finger protein 358 -3.18475
EIF2D eukaryotic translation initiation factor 2D -3.1843
DPYSL2 dihydropyrimidinase-like 2 -3.18141
CHPF chondroitin polymerizing factor -3.1814
DNASE1L1 deoxyribonuclease I-like 1 -3.17731
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -3.16529
CCNA1 cyclin A1 -3.16188
ALG12 ALG12, alpha-1,6-mannosyltransferase -3.16011
CPQ carboxypeptidase Q -3.15535
CA12 carbonic anhydrase XII -3.15212
FASN fatty acid synthase -3.15056
MAP4 microtubule-associated protein 4 -3.15035
CD81 CD81 molecule -3.14952
NOS2 nitric oxide synthase 2, inducible -3.14685
CFAP70 cilia and flagella associated protein 70 -3.14002
MKRN2 makorin ring finger protein 2 -3.13185
COPS7A COP9 signalosome subunit 7A -3.12962
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -3.12923
CASP2 caspase 2, apoptosis-related cysteine peptidase -3.12791
XKR8 XK, Kell blood group complex subunit-related family, member 8 -3.12486
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome -3.12033
GSTT1 glutathione S-transferase theta 1 -3.11745
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -3.11518
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -3.11274
PRRC2B proline-rich coiled-coil 2B -3.11065
AKT1 v-akt murine thymoma viral oncogene homolog 1 -3.11005
FAM168A family with sequence similarity 168, member A -3.10872
GJB5 gap junction protein, beta 5, 31.1kDa -3.10724
HOMER2 homer scaffolding protein 2 -3.10368
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -3.10042
CREB3L2 cAMP responsive element binding protein 3-like 2 -3.09771
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -3.09674
CALHM2 calcium homeostasis modulator 2 -3.09325
KATNB1 katanin p80 (WD repeat containing) subunit B 1 -3.08911
IQSEC1 IQ motif and Sec7 domain 1 -3.08058
TAC1 tachykinin, precursor 1 -3.07886
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -3.0762
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -3.06505
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -3.06008
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -3.0512
GATAD2A GATA zinc finger domain containing 2A -3.04994
ALOX15B arachidonate 15-lipoxygenase, type B -3.04786
EHBP1L1 EH domain binding protein 1-like 1 -3.04751
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -3.04354
TUBG1 tubulin, gamma 1 -3.03933
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -3.03866
AP2M1 adaptor-related protein complex 2, mu 1 subunit -3.03521
PABPC3 poly(A) binding protein, cytoplasmic 3 -3.03358
CALCB calcitonin-related polypeptide beta -3.03067
COL6A2 collagen, type VI, alpha 2 -3.0294
MKNK2 MAP kinase interacting serine/threonine kinase 2 -3.02911
NIT2 nitrilase family, member 2 -3.02872
RIN2 Ras and Rab interactor 2 -3.02596
HDLBP high density lipoprotein binding protein -3.02425
WDR6 WD repeat domain 6 -3.02164
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.0157
ADCY3 adenylate cyclase 3 -3.01391
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -3.00982
NDRG1 N-myc downstream regulated 1 -3.00822
TALDO1 transaldolase 1 -3.00565
BCAP31 B-cell receptor-associated protein 31 -3.00528
NCS1 neuronal calcium sensor 1 -3.00525
SRM spermidine synthase -3.00416