emphysema Gene Set
Genes
32 gene mutations causing the emphysema phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
| Symbol |
Name |
|
ADAMTS2
|
ADAM metallopeptidase with thrombospondin type 1 motif, 2
|
|
ADGRF5
|
adhesion G protein-coupled receptor F5
|
|
BLOC1S6
|
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
|
|
C11ORF73
|
chromosome 11 open reading frame 73
|
|
CRHR1
|
corticotropin releasing hormone receptor 1
|
|
CSF2
|
colony stimulating factor 2 (granulocyte-macrophage)
|
|
DBNL
|
drebrin-like
|
|
EFEMP2
|
EGF containing fibulin-like extracellular matrix protein 2
|
|
ELN
|
elastin
|
|
FBLN5
|
fibulin 5
|
|
FBN1
|
fibrillin 1
|
|
FLNA
|
filamin A, alpha
|
|
FUT8
|
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
|
|
HCK
|
HCK proto-oncogene, Src family tyrosine kinase
|
|
HMGN5
|
high mobility group nucleosome binding domain 5
|
|
HOXA5
|
homeobox A5
|
|
ITGB6
|
integrin, beta 6
|
|
KL
|
klotho
|
|
LIPA
|
lipase A, lysosomal acid, cholesterol esterase
|
|
LOX
|
lysyl oxidase
|
|
LRP2
|
low density lipoprotein receptor-related protein 2
|
|
LTBP4
|
latent transforming growth factor beta binding protein 4
|
|
LYST
|
lysosomal trafficking regulator
|
|
NPAS3
|
neuronal PAS domain protein 3
|
|
PDGFA
|
platelet-derived growth factor alpha polypeptide
|
|
PDGFRA
|
platelet-derived growth factor receptor, alpha polypeptide
|
|
RGN
|
regucalcin
|
|
SFTPC
|
surfactant protein C
|
|
SFTPD
|
surfactant protein D
|
|
SMPD3
|
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
|
|
TOM1L2
|
target of myb1-like 2 (chicken)
|
|
WWTR1
|
WW domain containing transcription regulator 1
|
