enalapril-2397 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the enalapril-2397 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APC adenomatous polyposis coli
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL4C ADP-ribosylation factor-like 4C
ASB1 ankyrin repeat and SOCS box containing 1
B9D1 B9 protein domain 1
BBS9 Bardet-Biedl syndrome 9
C11ORF30 chromosome 11 open reading frame 30
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL13 chemokine (C-C motif) ligand 13
CD59 CD59 molecule, complement regulatory protein
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEP250 centrosomal protein 250kDa
CPT1A carnitine palmitoyltransferase 1A (liver)
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSF1 colony stimulating factor 1 (macrophage)
CTNS cystinosin, lysosomal cystine transporter
DAPK3 death-associated protein kinase 3
DENND5B DENN/MADD domain containing 5B
EEA1 early endosome antigen 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPS8L3 EPS8-like 3
F2RL3 coagulation factor II (thrombin) receptor-like 3
FNTB farnesyltransferase, CAAX box, beta
FOXC1 forkhead box C1
GIF gastric intrinsic factor (vitamin B synthesis)
GPATCH4 G patch domain containing 4
GPR153 G protein-coupled receptor 153
GRTP1 growth hormone regulated TBC protein 1
HCFC1 host cell factor C1
HES1 hes family bHLH transcription factor 1
HIST1H3B histone cluster 1, H3b
HOXA1 homeobox A1
ICA1 islet cell autoantigen 1, 69kDa
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INE1 inactivation escape 1 (non-protein coding)
KIF13B kinesin family member 13B
KLF2 Kruppel-like factor 2
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT31 keratin 31, type I
LIMD1 LIM domains containing 1
LOC100286895 cell division cycle 27 homolog pseudogene
LOC100287590 uncharacterized LOC100287590
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LTBP1 latent transforming growth factor beta binding protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MKL2 MKL/myocardin-like 2
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NR1I2 nuclear receptor subfamily 1, group I, member 2
OMD osteomodulin
ONECUT2 one cut homeobox 2
OSBPL10 oxysterol binding protein-like 10
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDLIM3 PDZ and LIM domain 3
PLCH1 phospholipase C, eta 1
PLK4 polo-like kinase 4
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PODNL1 podocan-like 1
PPARD peroxisome proliferator-activated receptor delta
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
RAD52 RAD52 homolog (S. cerevisiae)
RUFY3 RUN and FYVE domain containing 3
RUNX1 runt-related transcription factor 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC35F5 solute carrier family 35, member F5
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SRPX sushi-repeat containing protein, X-linked
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
SUSD4 sushi domain containing 4
TBC1D17 TBC1 domain family, member 17
TEP1 telomerase-associated protein 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM180 transmembrane protein 180
TMLHE trimethyllysine hydroxylase, epsilon
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPM3 tropomyosin 3
TRAF4 TNF receptor-associated factor 4
TREM1 triggering receptor expressed on myeloid cells 1
TROVE2 TROVE domain family, member 2
TSC22D4 TSC22 domain family, member 4
U2AF2 U2 small nuclear RNA auxiliary factor 2
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
YLPM1 YLP motif containing 1
ZDHHC17 zinc finger, DHHC-type containing 17
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF500 zinc finger protein 500
ZNF639 zinc finger protein 639
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADTRP androgen-dependent TFPI-regulating protein
ALG12 ALG12, alpha-1,6-mannosyltransferase
APOLD1 apolipoprotein L domain containing 1
BAG4 BCL2-associated athanogene 4
BAHCC1 BAH domain and coiled-coil containing 1
BAHD1 bromo adjacent homology domain containing 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCORL1 BCL6 corepressor-like 1
BTBD2 BTB (POZ) domain containing 2
BTBD7 BTB (POZ) domain containing 7
C11ORF68 chromosome 11 open reading frame 68
C1ORF95 chromosome 1 open reading frame 95
CAMKMT calmodulin-lysine N-methyltransferase
CAPN15 calpain 15
CAPRIN2 caprin family member 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC85C coiled-coil domain containing 85C
CDA cytidine deaminase
CDK6 cyclin-dependent kinase 6
CEP97 centrosomal protein 97kDa
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLCF1 cardiotrophin-like cytokine factor 1
CSNK1G3 casein kinase 1, gamma 3
DEPDC5 DEP domain containing 5
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOC2A double C2-like domains, alpha
DSPP dentin sialophosphoprotein
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EMILIN2 elastin microfibril interfacer 2
EPHB6 EPH receptor B6
ERAP2 endoplasmic reticulum aminopeptidase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM163A family with sequence similarity 163, member A
FANCC Fanconi anemia, complementation group C
FBRS fibrosin
GCC1 GRIP and coiled-coil domain containing 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRAMD1B GRAM domain containing 1B
HAMP hepcidin antimicrobial peptide
HOOK2 hook microtubule-tethering protein 2
IL18 interleukin 18
IL4R interleukin 4 receptor
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
ITGB7 integrin, beta 7
JUNB jun B proto-oncogene
LTBP2 latent transforming growth factor beta binding protein 2
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MBD5 methyl-CpG binding domain protein 5
MCMBP minichromosome maintenance complex binding protein
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
NIPAL2 NIPA-like domain containing 2
NLK nemo-like kinase
NPFFR1 neuropeptide FF receptor 1
NTSR1 neurotensin receptor 1 (high affinity)
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PCYOX1 prenylcysteine oxidase 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDZD7 PDZ domain containing 7
PEX6 peroxisomal biogenesis factor 6
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLH polymerase (DNA directed), eta
POM121 POM121 transmembrane nucleoporin
POMZP3 POM121 and ZP3 fusion
PPT2 palmitoyl-protein thioesterase 2
PRKG2 protein kinase, cGMP-dependent, type II
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RAB33B RAB33B, member RAS oncogene family
RFXAP regulatory factor X-associated protein
RNF167 ring finger protein 167
RPL23AP32 ribosomal protein L23a pseudogene 32
SAMD9 sterile alpha motif domain containing 9
SKI SKI proto-oncogene
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
STEAP3 STEAP family member 3, metalloreductase
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUOX sulfite oxidase
TESK1 testis-specific kinase 1
TET3 tet methylcytosine dioxygenase 3
TGM5 transglutaminase 5
TMEM209 transmembrane protein 209
TMEM246 transmembrane protein 246
TMEM53 transmembrane protein 53
TNIP1 TNFAIP3 interacting protein 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
USP27X ubiquitin specific peptidase 27, X-linked
WFDC2 WAP four-disulfide core domain 2
XAB2 XPA binding protein 2
ZBTB10 zinc finger and BTB domain containing 10
ZC4H2 zinc finger, C4H2 domain containing
ZNF222 zinc finger protein 222
ZNF493 zinc finger protein 493
ZNF552 zinc finger protein 552
ZNF696 zinc finger protein 696
ZNF747 zinc finger protein 747