endocardial cushion development Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. (Gene Ontology, GO_0003197)
External Link http://amigo.geneontology.org/amigo/term/GO:0003197
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Genes

23 genes participating in the endocardial cushion development biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACVRL1 activin A receptor type II-like 1
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMPR1A bone morphogenetic protein receptor, type IA
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CRELD1 cysteine-rich with EGF-like domains 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
ENG endoglin
FOXF1 forkhead box F1
GATA4 GATA binding protein 4
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEYL hes-related family bHLH transcription factor with YRPW motif-like
ISL1 ISL LIM homeobox 1
MDM4 MDM4, p53 regulator
NANOS3 nanos homolog 3 (Drosophila)
NOTCH1 notch 1
PROC protein C (inactivator of coagulation factors Va and VIIIa)
SMAD2 SMAD family member 2
SOX9 SRY (sex determining region Y)-box 9
TBX2 T-box 2
TBX20 T-box 20
TGFB2 transforming growth factor, beta 2