endocardium disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A heart disease that is located_in the innermost layer of tissue that lines the chambers of the heart. (Human Disease Ontology, DOID_0050825)
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Genes

281 genes co-occuring with the disease endocardium disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PRTN3 proteinase 3 0.667073
CRP C-reactive protein, pentraxin-related 0.47215
FN1 fibronectin 1 0.420341
DLL1 delta-like 1 (Drosophila) 0.419142
F3 coagulation factor III (thromboplastin, tissue factor) 0.378736
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.371921
F2 coagulation factor II (thrombin) 0.366744
AMDHD2 amidohydrolase domain containing 2 0.344501
CD79A CD79a molecule, immunoglobulin-associated alpha 0.337242
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 0.281868
FAM155B family with sequence similarity 155, member B 0.280367
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.2763
LECT1 leukocyte cell derived chemotaxin 1 0.26351
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.248905
MTM1 myotubularin 1 0.246448
PLAT plasminogen activator, tissue 0.244205
SUMF2 sulfatase modifying factor 2 0.240777
ERAS ES cell expressed Ras 0.224196
GLRXP3 glutaredoxin (thioltransferase) pseudogene 3 0.212203
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.211194
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.192908
CAT catalase 0.183658
CD4 CD4 molecule 0.180652
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.172291
MPO myeloperoxidase 0.165391
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.162707
AQP9 aquaporin 9 0.160313
TAZ tafazzin 0.156678
MSRA methionine sulfoxide reductase A 0.155919
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.154828
MATK megakaryocyte-associated tyrosine kinase 0.153116
C1QBP complement component 1, q subcomponent binding protein 0.152434
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.150485
AGRN agrin 0.150216
IVD isovaleryl-CoA dehydrogenase 0.149464
LCK LCK proto-oncogene, Src family tyrosine kinase 0.149386
F5 coagulation factor V (proaccelerin, labile factor) 0.148796
LBP lipopolysaccharide binding protein 0.147918
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.147273
TBX1 T-box 1 0.146794
PEX19 peroxisomal biogenesis factor 19 0.146667
SSRP1 structure specific recognition protein 1 0.146198
C6ORF25 chromosome 6 open reading frame 25 0.145902
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.145881
IL6 interleukin 6 0.145856
FAM120A family with sequence similarity 120A 0.145548
ALB albumin 0.145482
LEFTY1 left-right determination factor 1 0.145482
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.145459
NEBL nebulette 0.145394
PRB3 proline-rich protein BstNI subfamily 3 0.14521
OR5K1 olfactory receptor, family 5, subfamily K, member 1 0.144845
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.144815
OR3A1 olfactory receptor, family 3, subfamily A, member 1 0.144806
FTL ferritin, light polypeptide 0.144787
FTH1 ferritin, heavy polypeptide 1 0.144785
MUC21 mucin 21, cell surface associated 0.144724
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.144703
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 0.144637
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.14459
CA5B carbonic anhydrase VB, mitochondrial 0.14455
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.144529
ACTN2 actinin, alpha 2 0.144501
PIDD1 p53-induced death domain protein 1 0.144459
MARCO macrophage receptor with collagenous structure 0.144413
GNPDA1 glucosamine-6-phosphate deaminase 1 0.144324
TNNI3 troponin I type 3 (cardiac) 0.144254
PER2 period circadian clock 2 0.144112
F12 coagulation factor XII (Hageman factor) 0.143974
HPR haptoglobin-related protein 0.143937
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.143893
CXCL16 chemokine (C-X-C motif) ligand 16 0.143844
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.143794
LYZ lysozyme 0.143792
BLVRA biliverdin reductase A 0.143769
HN1 hematological and neurological expressed 1 0.143757
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.143707
IGLV9-49 immunoglobulin lambda variable 9-49 0.143707
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 0.143703
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.143663
PLG plasminogen 0.14365
ICAM1 intercellular adhesion molecule 1 0.143623
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 0.143588
TRIM21 tripartite motif containing 21 0.143494
RTP4 receptor (chemosensory) transporter protein 4 0.143452
PER1 period circadian clock 1 0.143438
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.143336
CS citrate synthase 0.143336
VCAM1 vascular cell adhesion molecule 1 0.143274
SRPX2 sushi-repeat containing protein, X-linked 2 0.143167
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.143124
BAG6 BCL2-associated athanogene 6 0.143113
ENO1 enolase 1, (alpha) 0.143077
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) 0.142997
PRF1 perforin 1 (pore forming protein) 0.142972
GAA glucosidase, alpha; acid 0.142967
VWF von Willebrand factor 0.142953
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 0.142827
PHF12 PHD finger protein 12 0.142771
CFP complement factor properdin 0.142703
LNX2 ligand of numb-protein X 2 0.142661
JMJD6 jumonji domain containing 6 0.142561
TNF tumor necrosis factor 0.142549
MOGS mannosyl-oligosaccharide glucosidase 0.142542
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.142466
PTCH1 patched 1 0.142449
GAB2 GRB2-associated binding protein 2 0.142426
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.142213
FBXO21 F-box protein 21 0.142152
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.142127
F8 coagulation factor VIII, procoagulant component 0.142109
CXCL8 chemokine (C-X-C motif) ligand 8 0.142033
TROVE2 TROVE domain family, member 2 0.142022
RGMB repulsive guidance molecule family member b 0.141828
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.141566
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.141473
A1BG alpha-1-B glycoprotein 0.141369
S100A11 S100 calcium binding protein A11 0.141364
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.141258
ATG4C autophagy related 4C, cysteine peptidase 0.141149
HM13 histocompatibility (minor) 13 0.141139
TLR2 toll-like receptor 2 0.141135
CCDC112 coiled-coil domain containing 112 0.14106
KIF21A kinesin family member 21A 0.140998
IDUA iduronidase, alpha-L- 0.14096
NAAA N-acylethanolamine acid amidase 0.140897
NEUROD4 neuronal differentiation 4 0.140877
NLRC5 NLR family, CARD domain containing 5 0.140748
PLEK2 pleckstrin 2 0.140009
TMEM131 transmembrane protein 131 0.139532
ODC1 ornithine decarboxylase 1 0.139449
GPR84 G protein-coupled receptor 84 0.139422
SLURP1 secreted LY6/PLAUR domain containing 1 0.139403
FABP3 fatty acid binding protein 3, muscle and heart 0.13939
ESYT1 extended synaptotagmin-like protein 1 0.139324
PNP purine nucleoside phosphorylase 0.139317
PRSS21 protease, serine, 21 (testisin) 0.139122
ST20 suppressor of tumorigenicity 20 0.139004
ARRDC3 arrestin domain containing 3 0.138332
HP haptoglobin 0.1383
PCSK6 proprotein convertase subtilisin/kexin type 6 0.138214
LPO lactoperoxidase 0.13811
APEH acylaminoacyl-peptide hydrolase 0.137988
GRB2 growth factor receptor-bound protein 2 0.137963
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.13788
ANGPT1 angiopoietin 1 0.137711
APOH apolipoprotein H (beta-2-glycoprotein I) 0.137676
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.137616
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.137511
ARMC10 armadillo repeat containing 10 0.13744
EMC3 ER membrane protein complex subunit 3 0.137093
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.137046
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.136904
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.136846
FBN1 fibrillin 1 0.136531
TNMD tenomodulin 0.136501
CCNE1 cyclin E1 0.136388
ZYX zyxin 0.136347
BTNL2 butyrophilin-like 2 0.136316
SCPEP1 serine carboxypeptidase 1 0.136275
NEUROD2 neuronal differentiation 2 0.136243
FIP1L1 factor interacting with PAPOLA and CPSF1 0.136031
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.13568
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.135646
SCIN scinderin 0.135612
CNOT8 CCR4-NOT transcription complex, subunit 8 0.135301
IL10 interleukin 10 0.135098
IL16 interleukin 16 0.13464
ALLC allantoicase 0.134551
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.134395
EPX eosinophil peroxidase 0.134317
IVL involucrin 0.13425
NQO2 NAD(P)H dehydrogenase, quinone 2 0.134197
GLUL glutamate-ammonia ligase 0.134103
WDFY2 WD repeat and FYVE domain containing 2 0.134089
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.133939
CNOT1 CCR4-NOT transcription complex, subunit 1 0.133531
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.133502
RNF19B ring finger protein 19B 0.133342
PRIMA1 proline rich membrane anchor 1 0.133298
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.133163
CDAN1 codanin 1 0.132905
SECISBP2 SECIS binding protein 2 0.132577
RND3 Rho family GTPase 3 0.132545
TOX thymocyte selection-associated high mobility group box 0.132465
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.132318
MTUS1 microtubule associated tumor suppressor 1 0.132204
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.131953
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.131764
LTF lactotransferrin 0.131712
THBD thrombomodulin 0.131643
CSF1R colony stimulating factor 1 receptor 0.131448
ELOVL6 ELOVL fatty acid elongase 6 0.131288
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 0.131269
POMC proopiomelanocortin 0.130919
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.1309
CCL23 chemokine (C-C motif) ligand 23 0.130787
AURKC aurora kinase C 0.130768
TIMP1 TIMP metallopeptidase inhibitor 1 0.130731
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.130577
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.130577
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.130499
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 0.130264
KRT83 keratin 83, type II 0.130084
ZNF77 zinc finger protein 77 0.130064
C5AR1 complement component 5a receptor 1 0.130044
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.130044
SCG5 secretogranin V 0.130024
KMT2A lysine (K)-specific methyltransferase 2A 0.129901
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 0.129901
ADGRV1 adhesion G protein-coupled receptor V1 0.129818
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.12927
STAG2 stromal antigen 2 0.12927
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.129072
CYTIP cytohesin 1 interacting protein 0.128962
TCEA1 transcription elongation factor A (SII), 1 0.128896
TLR4 toll-like receptor 4 0.128783
GUSB glucuronidase, beta 0.128647
OCM2 oncomodulin 2 0.128348
ADSL adenylosuccinate lyase 0.12823
ICA1 islet cell autoantigen 1, 69kDa 0.128183
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.128136
PKP2 plakophilin 2 0.1278
TXNRD1 thioredoxin reductase 1 0.127654
ALPPL2 alkaline phosphatase, placental-like 2 0.127579
SOCS5 suppressor of cytokine signaling 5 0.127554
ALPP alkaline phosphatase, placental 0.127554
ALPL alkaline phosphatase, liver/bone/kidney 0.127504
KARS lysyl-tRNA synthetase 0.127504
OCM oncomodulin 0.127178
NPB neuropeptide B 0.126868
KAT8 K(lysine) acetyltransferase 8 0.126738
TSN translin 0.126711
PF4 platelet factor 4 0.126631
SELE selectin E 0.126551
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.126417
FUT2 fucosyltransferase 2 (secretor status included) 0.126118
GH2 growth hormone 2 0.126035
ATOH1 atonal homolog 1 (Drosophila) 0.1253
ADORA2B adenosine A2b receptor 0.125241
TNNT2 troponin T type 2 (cardiac) 0.124857
IARS isoleucyl-tRNA synthetase 0.124828
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.124828
RNH1 ribonuclease/angiogenin inhibitor 1 0.124798
C1S complement component 1, s subcomponent 0.124341
PTH1R parathyroid hormone 1 receptor 0.12431
HTRA3 HtrA serine peptidase 3 0.124122
IFI30 interferon, gamma-inducible protein 30 0.123996
IGLV3-10 immunoglobulin lambda variable 3-10 0.123965
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.123615
CD5 CD5 molecule 0.123549
RAET1E retinoic acid early transcript 1E 0.123223
SEBOX SEBOX homeobox 0.123125
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 0.122956
CFH complement factor H 0.122855
PNMA1 paraneoplastic Ma antigen 1 0.122687
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.122308
HTRA1 HtrA serine peptidase 1 0.122308
HCAR2 hydroxycarboxylic acid receptor 2 0.122134
IL1B interleukin 1, beta 0.122064
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.121851
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.121707
GLB1 galactosidase, beta 1 0.120976
KDR kinase insert domain receptor 0.120939
GPR162 G protein-coupled receptor 162 0.120753
CD99 CD99 molecule 0.120715
ALOX15 arachidonate 15-lipoxygenase 0.120715
RAD23B RAD23 homolog B (S. cerevisiae) 0.120678
WIF1 WNT inhibitory factor 1 0.120601
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.120409
MAPK8 mitogen-activated protein kinase 8 0.12037
ANXA5 annexin A5 0.120255
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.120178
FBL fibrillarin 0.120178
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.119746
AHR aryl hydrocarbon receptor 0.118527
RFXANK regulatory factor X-associated ankyrin-containing protein 0.118187
MED28 mediator complex subunit 28 0.118145
HLA-E major histocompatibility complex, class I, E 0.11806
EVC Ellis van Creveld protein 0.117933
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.11776