endocardium Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A thin serous membrane lining the cavities of the heart. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000387)
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Genes

347 proteins co-occuring with the tissue endocardium in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 1.98313
SCN5A sodium channel, voltage gated, type V alpha subunit 1.85019
TBX20 T-box 20 1.75974
NOTCH1 notch 1 1.62108
EFS embryonal Fyn-associated substrate 1.54102
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 1.52569
GATA4 GATA binding protein 4 1.4575
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 1.43061
GATA5 GATA binding protein 5 1.42876
PTH1R parathyroid hormone 1 receptor 1.35041
IRX5 iroquois homeobox 5 1.32732
HAS2 hyaluronan synthase 2 1.30478
GJA1 gap junction protein, alpha 1, 43kDa 1.28412
TERF2 telomeric repeat binding factor 2 1.26218
FBLN1 fibulin 1 1.26039
IRX1 iroquois homeobox 1 1.25726
EDN1 endothelin 1 1.25279
TMEM2 transmembrane protein 2 1.24833
TPTE transmembrane phosphatase with tensin homology 1.20111
TGFB3 transforming growth factor, beta 3 1.19756
NPPA natriuretic peptide A 1.17491
TBX5 T-box 5 1.15628
VCAN versican 1.15052
BMPR1A bone morphogenetic protein receptor, type IA 1.14653
NKX2-5 NK2 homeobox 5 1.139
CA5B carbonic anhydrase VB, mitochondrial 1.13634
EVC2 Ellis van Creveld syndrome 2 1.11331
TWIST1 twist family bHLH transcription factor 1 1.1027
GJC1 gap junction protein, gamma 1, 45kDa 1.09783
TGFB1 transforming growth factor, beta 1 1.09651
TBX2 T-box 2 1.08899
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 1.08722
BMP4 bone morphogenetic protein 4 1.0806
BMP2 bone morphogenetic protein 2 1.08015
GJA5 gap junction protein, alpha 5, 40kDa 1.04708
CRIP2 cysteine-rich protein 2 1.04533
FN1 fibronectin 1 1.03961
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 1.01681
NOS3 nitric oxide synthase 3 (endothelial cell) 1.00632
EDNRA endothelin receptor type A 1.00414
FBLN2 fibulin 2 0.991509
TGFB2 transforming growth factor, beta 2 0.974583
GATA6 GATA binding protein 6 0.954271
NRG1 neuregulin 1 0.951685
VWF von Willebrand factor 0.946947
VEGFA vascular endothelial growth factor A 0.925907
SCN3B sodium channel, voltage gated, type III beta subunit 0.923767
FGF16 fibroblast growth factor 16 0.921627
HAND2 heart and neural crest derivatives expressed 2 0.909666
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.908814
IRX3 iroquois homeobox 3 0.905831
RYR2 ryanodine receptor 2 (cardiac) 0.885862
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 0.885862
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.884591
GLB1 galactosidase, beta 1 0.879512
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.864312
THBD thrombomodulin 0.861363
ACE angiotensin I converting enzyme 0.850005
BMP10 bone morphogenetic protein 10 0.847904
KNG1 kininogen 1 0.846644
FOXRED1 FAD-dependent oxidoreductase domain containing 1 0.839091
ISL1 ISL LIM homeobox 1 0.834899
MSX2 msh homeobox 2 0.83448
TNNI3 troponin I type 3 (cardiac) 0.833223
MANEAL mannosidase, endo-alpha-like 0.830291
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.828616
IRX6 iroquois homeobox 6 0.816904
IRF6 interferon regulatory factor 6 0.813144
TLL1 tolloid-like 1 0.802293
RAB39B RAB39B, member RAS oncogene family 0.792709
ADAM19 ADAM metallopeptidase domain 19 0.777325
POPDC3 popeye domain containing 3 0.776909
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.764468
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 0.764054
ALB albumin 0.758259
ENHO energy homeostasis associated 0.757845
JARID2 jumonji, AT rich interactive domain 2 0.747102
TAL1 T-cell acute lymphocytic leukemia 1 0.746277
MSTO1 misato 1, mitochondrial distribution and morphology regulator 0.743801
CDH5 cadherin 5, type 2 (vascular endothelium) 0.742152
MYBPC3 myosin binding protein C, cardiac 0.733089
JAG1 jagged 1 0.731854
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.725685
SMAD6 SMAD family member 6 0.724863
ARHGAP29 Rho GTPase activating protein 29 0.721577
ALG10B ALG10B, alpha-1,2-glucosyltransferase 0.721166
HAPLN1 hyaluronan and proteoglycan link protein 1 0.718292
DNAH8 dynein, axonemal, heavy chain 8 0.717882
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.71009
ARL5A ADP-ribosylation factor-like 5A 0.70886
LIMS1 LIM and senescent cell antigen-like domains 1 0.707631
ACSL1 acyl-CoA synthetase long-chain family member 1 0.703945
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.701899
MSX1 msh homeobox 1 0.696989
CRELD1 cysteine-rich with EGF-like domains 1 0.695354
CGNL1 cingulin-like 1 0.693311
TBX18 T-box 18 0.691268
PTPRM protein tyrosine phosphatase, receptor type, M 0.688
F3 coagulation factor III (thromboplastin, tissue factor) 0.688
BRI3BP BRI3 binding protein 0.680656
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 0.67984
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 0.67658
HAND1 heart and neural crest derivatives expressed 1 0.67495
ECE1 endothelin converting enzyme 1 0.671692
SOX9 SRY (sex determining region Y)-box 9 0.669657
BMPR1B bone morphogenetic protein receptor, type IB 0.665995
GUCY2C guanylate cyclase 2C 0.663962
NPR1 natriuretic peptide receptor 1 0.661929
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.659897
BMX BMX non-receptor tyrosine kinase 0.652183
POPDC2 popeye domain containing 2 0.65056
NOG noggin 0.644479
FBN2 fibrillin 2 0.63638
F8 coagulation factor VIII, procoagulant component 0.635572
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.633953
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.627485
CRLS1 cardiolipin synthase 1 0.622639
MLX MLX, MAX dimerization protein 0.619814
NPY neuropeptide Y 0.6182
TNC tenascin C 0.617796
PLN phospholamban 0.614167
MEF2C myocyte enhancer factor 2C 0.613764
MNX1 motor neuron and pancreas homeobox 1 0.596058
CHGA chromogranin A 0.584422
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.58242
SLA2 Src-like-adaptor 2 0.580017
TNNT2 troponin T type 2 (cardiac) 0.578816
CASQ2 calsequestrin 2 (cardiac muscle) 0.577615
RAET1E retinoic acid early transcript 1E 0.576816
SOX4 SRY (sex determining region Y)-box 4 0.571619
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.57042
PHF12 PHD finger protein 12 0.567626
PARD6A par-6 family cell polarity regulator alpha 0.560847
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.55607
ERBB3 erb-b2 receptor tyrosine kinase 3 0.552888
FGF20 fibroblast growth factor 20 0.549312
C10ORF10 chromosome 10 open reading frame 10 0.547724
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.533856
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 0.533856
TTN titin 0.53346
CORO1B coronin, actin binding protein, 1B 0.533065
HEYL hes-related family bHLH transcription factor with YRPW motif-like 0.529508
CS citrate synthase 0.527928
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.527534
PLVAP plasmalemma vesicle associated protein 0.526744
EFNA1 ephrin-A1 0.524771
AMH anti-Mullerian hormone 0.519253
THOP1 thimet oligopeptidase 1 0.510992
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.503141
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 0.492963
TIMP4 TIMP metallopeptidase inhibitor 4 0.492182
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 0.490229
FGF8 fibroblast growth factor 8 (androgen-induced) 0.482817
TNRC6A trinucleotide repeat containing 6A 0.48048
DOK4 docking protein 4 0.479312
GFRA3 GDNF family receptor alpha 3 0.477756
EFNB2 ephrin-B2 0.475812
FLT1 fms-related tyrosine kinase 1 0.473092
EDN3 endothelin 3 0.472315
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.471927
RASIP1 Ras interacting protein 1 0.471539
ODAM odontogenic, ameloblast asssociated 0.468436
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.468048
MECOM MDS1 and EVI1 complex locus 0.463013
KIAA0101 KIAA0101 0.463013
GJA4 gap junction protein, alpha 4, 37kDa 0.459918
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.459918
TH tyrosine hydroxylase 0.459145
PLAT plasminogen activator, tissue 0.458373
TBX1 T-box 1 0.4576
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.456828
MMP2 matrix metallopeptidase 2 0.45374
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.452969
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.452198
KLF10 Kruppel-like factor 10 0.451428
MBNL1 muscleblind-like splicing regulator 1 0.450271
BLVRA biliverdin reductase A 0.448346
RAB5B RAB5B, member RAS oncogene family 0.445653
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.444884
ZFPM2 zinc finger protein, FOG family member 2 0.443731
HHEX hematopoietically expressed homeobox 0.443347
KALRN kalirin, RhoGEF kinase 0.443347
ADRB1 adrenoceptor beta 1 0.443347
MB myoglobin 0.441426
TAC1 tachykinin, precursor 1 0.439123
TCEA1 transcription elongation factor A (SII), 1 0.438739
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.437205
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.433757
ETV1 ets variant 1 0.433374
IGLV2-14 immunoglobulin lambda variable 2-14 0.432608
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.427254
ERBB4 erb-b2 receptor tyrosine kinase 4 0.423436
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.422292
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.417718
IL17C interleukin 17C 0.416195
ALG10 ALG10, alpha-1,2-glucosyltransferase 0.413912
APLNR apelin receptor 0.411251
POSTN periostin, osteoblast specific factor 0.410111
PRSS30P protease, serine, 30, pseudogene 0.405935
PARP15 poly (ADP-ribose) polymerase family, member 15 0.405555
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.404797
ACTC1 actin, alpha, cardiac muscle 1 0.402523
GRAP GRB2-related adaptor protein 0.401007
COL12A1 collagen, type XII, alpha 1 0.40025
NPNT nephronectin 0.399492
HBA1 hemoglobin, alpha 1 0.399492
FAM131C family with sequence similarity 131, member C 0.396465
GATA2 GATA binding protein 2 0.396465
ADM adrenomedullin 0.394953
ERAS ES cell expressed Ras 0.394197
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.393442
EPHA3 EPH receptor A3 0.392686
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.392309
LYZ lysozyme 0.390044
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 0.387404
HBA2 hemoglobin, alpha 2 0.387027
FGF2 fibroblast growth factor 2 (basic) 0.387027
PITX2 paired-like homeodomain 2 0.38326
ZYX zyxin 0.38326
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.382131
MYSM1 Myb-like, SWIRM and MPN domains 1 0.37687
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.375743
ACVR1 activin A receptor, type I 0.375743
GFRA2 GDNF family receptor alpha 2 0.374618
TMSB4X thymosin beta 4, X-linked 0.374243
FOXC1 forkhead box C1 0.373118
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.372743
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.368998
SMAD4 SMAD family member 4 0.367876
PPT1 palmitoyl-protein thioesterase 1 0.363393
MON1A MON1 secretory trafficking family member A 0.361155
RNASE3 ribonuclease, RNase A family, 3 0.358174
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.356686
NEFM neurofilament, medium polypeptide 0.355198
CIC capicua transcriptional repressor 0.354826
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.354084
FTL ferritin, light polypeptide 0.352227
SOD2 superoxide dismutase 2, mitochondrial 0.351485
DSE dermatan sulfate epimerase 0.347778
NLRP10 NLR family, pyrin domain containing 10 0.347408
NPAT nuclear protein, ataxia-telangiectasia locus 0.347038
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.345928
IRX4 iroquois homeobox 4 0.345928
FTH1 ferritin, heavy polypeptide 1 0.345188
HDAC5 histone deacetylase 5 0.34334
OAZ3 ornithine decarboxylase antizyme 3 0.342233
CD34 CD34 molecule 0.341495
PRB3 proline-rich protein BstNI subfamily 3 0.341126
APLN apelin 0.339282
RXRA retinoid X receptor, alpha 0.338914
SMAD2 SMAD family member 2 0.338545
CSRP2 cysteine and glycine-rich protein 2 0.338177
ACKR3 atypical chemokine receptor 3 0.33744
TPM1 tropomyosin 1 (alpha) 0.3356
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.335233
COL13A1 collagen, type XIII, alpha 1 0.333396
GYLTL1B glycosyltransferase-like 1B 0.33156
SNAI1 snail family zinc finger 1 0.330827
MMP9 matrix metallopeptidase 9 0.33046
UTS2 urotensin 2 0.32753
PARP14 poly (ADP-ribose) polymerase family, member 14 0.326432
NOVA2 neuro-oncological ventral antigen 2 0.326067
SPATA5 spermatogenesis associated 5 0.324605
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.323144
FOXP1 forkhead box P1 0.322414
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.322414
FBL fibrillarin 0.319863
F2 coagulation factor II (thrombin) 0.319134
FOXO4 forkhead box O4 0.314046
TNNI2 troponin I type 2 (skeletal, fast) 0.31187
HTRA2 HtrA serine peptidase 2 0.309335
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.307889
ETV2 ets variant 2 0.307528
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.305361
ZBTB48 zinc finger and BTB domain containing 48 0.305001
CMA1 chymase 1, mast cell 0.30464
PRKD2 protein kinase D2 0.299242
RREB1 ras responsive element binding protein 1 0.29673
VCAM1 vascular cell adhesion molecule 1 0.295297
WNT9A wingless-type MMTV integration site family, member 9A 0.293508
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.293151
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.292793
EPX eosinophil peroxidase 0.290652
WNT1 wingless-type MMTV integration site family, member 1 0.28887
COL2A1 collagen, type II, alpha 1 0.284253
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.280717
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 0.279307
BVES blood vessel epicardial substance 0.276846
NOS1 nitric oxide synthase 1 (neuronal) 0.276495
DAND5 DAN domain family member 5, BMP antagonist 0.274394
PPIF peptidylprolyl isomerase F 0.273696
COL5A2 collagen, type V, alpha 2 0.2723
ACAN aggrecan 0.270561
GZMM granzyme M (lymphocyte met-ase 1) 0.270214
SLA Src-like-adaptor 0.269867
NCAN neurocan 0.268828
DAB2IP DAB2 interacting protein 0.267791
USO1 USO1 vesicle transport factor 0.267446
CRP C-reactive protein, pentraxin-related 0.266069
TAGLN transgelin 0.265381
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 0.264011
PDLIM1 PDZ and LIM domain 1 0.263669
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.260945
MYH4 myosin, heavy chain 4, skeletal muscle 0.259254
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 0.259254
CD59 CD59 molecule, complement regulatory protein 0.258917
WNT2 wingless-type MMTV integration site family member 2 0.25858
IRX2 iroquois homeobox 2 0.257907
SEBOX SEBOX homeobox 0.256234
NPR3 natriuretic peptide receptor 3 0.255567
WT1 Wilms tumor 1 0.255234
FBLL1 fibrillarin-like 1 0.252261
A1BG alpha-1-B glycoprotein 0.250301
FRZB frizzled-related protein 0.249653
IDUA iduronidase, alpha-L- 0.247719
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 0.245491
SULT4A1 sulfotransferase family 4A, member 1 0.243918
TNF tumor necrosis factor 0.243918
PID1 phosphotyrosine interaction domain containing 1 0.242672
NOTCH4 notch 4 0.240216
ECE2 endothelin converting enzyme 2 0.239307
MORF4 mortality factor 4 (pseudogene) 0.239007
PAX3 paired box 3 0.234302
CALCRL calcitonin receptor-like 0.234302
TTR transthyretin 0.234016
CALCA calcitonin-related polypeptide alpha 0.229032
SMAD3 SMAD family member 3 0.226411
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.226155
MAN2B1 mannosidase, alpha, class 2B, member 1 0.224893
EMILIN1 elastin microfibril interfacer 1 0.224398
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.223906
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.222699
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.220831
GLRA1 glycine receptor, alpha 1 0.220378
IGLV3-9 immunoglobulin lambda variable 3-9 (gene/pseudogene) 0.219485
SOX17 SRY (sex determining region Y)-box 17 0.219264
ACHE acetylcholinesterase (Yt blood group) 0.218398
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.218186
MRC1 mannose receptor, C type 1 0.217762
MDM4 MDM4, p53 regulator 0.217139
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 0.216126
CD68 CD68 molecule 0.215534
CPLX1 complexin 1 0.214576
MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.21365
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 0.213471
ITGA7 integrin, alpha 7 0.213112
TPM4 tropomyosin 4 0.212761