endometriosis Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs. (Experimental Factor Ontology, EFO_0001065)
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Genes

85 genes associated with the disease endometriosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
AHR aryl hydrocarbon receptor
AHSG alpha-2-HS-glycoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
AR androgen receptor
ARNT aryl hydrocarbon receptor nuclear translocator
CCL5 chemokine (C-C motif) ligand 5
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2B-AS1 CDKN2B antisense RNA 1
CLOCK clock circadian regulator
COMT catechol-O-methyltransferase
CXCL8 chemokine (C-X-C motif) ligand 8
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
EGFR epidermal growth factor receptor
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGF1 fibroblast growth factor 1 (acidic)
FSHR follicle stimulating hormone receptor
GALT galactose-1-phosphate uridylyltransferase
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOXA10 homeobox A10
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IL10 interleukin 10
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL2RB interleukin 2 receptor, beta
IL4 interleukin 4
IL6 interleukin 6
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
LTA lymphotoxin alpha
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NFE2L3 nuclear factor, erythroid 2-like 3
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NRIP1 nuclear receptor interacting protein 1
OGG1 8-oxoguanine DNA glycosylase
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLG plasminogen
PPARG peroxisome proliferator-activated receptor gamma
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TACR1 tachykinin receptor 1
TGFB1 transforming growth factor, beta 1
TIMP2 TIMP metallopeptidase inhibitor 2
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WNT4 wingless-type MMTV integration site family, member 4
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1