endopeptidase regulator activity Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. (Gene Ontology, GO_0061135)
External Link http://amigo.geneontology.org/amigo/term/GO:0061135
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Genes

50 genes performing the endopeptidase regulator activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADRM1 adhesion regulating molecule 1
AHSG alpha-2-HS-glycoprotein
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
CST3 cystatin C
CST7 cystatin F (leukocystatin)
CSTB cystatin B (stefin B)
ERC2 ELKS/RAB6-interacting/CAST family member 2
GBP2 guanylate binding protein 2, interferon-inducible
GBP5 guanylate binding protein 5
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
LGMN legumain
LPA lipoprotein, Lp(a)
MALT1 MALT1 paracaspase
NCSTN nicastrin
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NLRC4 NLR family, CARD domain containing 4
OPRPN opiorphin prepropeptide
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PI3 peptidase inhibitor 3, skin-derived
PROS1 protein S (alpha)
PSENEN presenilin enhancer gamma secretase subunit
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PZP pregnancy-zone protein
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RENBP renin binding protein
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SGPP2 sphingosine-1-phosphate phosphatase 2
SLPI secretory leukocyte peptidase inhibitor
SMR3A submaxillary gland androgen regulated protein 3A
SMR3B submaxillary gland androgen regulated protein 3B
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBS1 thrombospondin 1
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VSIR V-set immunoregulatory receptor
WFDC2 WAP four-disulfide core domain 2