enilconazole-3139 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the enilconazole-3139 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AKAP5 A kinase (PRKA) anchor protein 5
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AMPH amphiphysin
ATF6B activating transcription factor 6 beta
BPI bactericidal/permeability-increasing protein
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF16 chromosome 11 open reading frame 16
C16ORF45 chromosome 16 open reading frame 45
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CFAP45 cilia and flagella associated protein 45
CLCN7 chloride channel, voltage-sensitive 7
CNGA1 cyclic nucleotide gated channel alpha 1
COL10A1 collagen, type X, alpha 1
COL5A2 collagen, type V, alpha 2
CPN2 carboxypeptidase N, polypeptide 2
CREM cAMP responsive element modulator
CYB5R2 cytochrome b5 reductase 2
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DCT dopachrome tautomerase
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEPTOR DEP domain containing MTOR-interacting protein
DGAT1 diacylglycerol O-acyltransferase 1
ENG endoglin
EYA3 EYA transcriptional coactivator and phosphatase 3
FAAH fatty acid amide hydrolase
FAM127B family with sequence similarity 127, member B
FAM149A family with sequence similarity 149, member A
FBXL7 F-box and leucine-rich repeat protein 7
FBXO31 F-box protein 31
FGB fibrinogen beta chain
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR85 G protein-coupled receptor 85
HCG4 HLA complex group 4 (non-protein coding)
HLA-F major histocompatibility complex, class I, F
HOXA10 homeobox A10
IGFBP3 insulin-like growth factor binding protein 3
INHBC inhibin, beta C
INO80B INO80 complex subunit B
JAG1 jagged 1
KDM5B lysine (K)-specific demethylase 5B
KDM8 lysine (K)-specific demethylase 8
KIAA1654 KIAA1654 protein
LENEP lens epithelial protein
MID1 midline 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MLXIPL MLX interacting protein-like
MYBPC3 myosin binding protein C, cardiac
NCS1 neuronal calcium sensor 1
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NTSR1 neurotensin receptor 1 (high affinity)
OLFM1 olfactomedin 1
OMG oligodendrocyte myelin glycoprotein
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4C phosphodiesterase 4C, cAMP-specific
PGAM2 phosphoglycerate mutase 2 (muscle)
PHF8 PHD finger protein 8
PLA2G3 phospholipase A2, group III
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PON3 paraoxonase 3
PPAP2B phosphatidic acid phosphatase type 2B
PPT2 palmitoyl-protein thioesterase 2
QTRT1 queuine tRNA-ribosyltransferase 1
RBPMS RNA binding protein with multiple splicing
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RECQL5 RecQ protein-like 5
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPGRIP1L RPGRIP1-like
RPL10 ribosomal protein L10
SBNO2 strawberry notch homolog 2 (Drosophila)
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH3GL3 SH3-domain GRB2-like 3
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SOCS2 suppressor of cytokine signaling 2
SORBS3 sorbin and SH3 domain containing 3
SOX12 SRY (sex determining region Y)-box 12
SPHK2 sphingosine kinase 2
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SULT4A1 sulfotransferase family 4A, member 1
TICAM1 toll-like receptor adaptor molecule 1
TJP3 tight junction protein 3
TNK1 tyrosine kinase, non-receptor, 1
TPMT thiopurine S-methyltransferase
TSC22D2 TSC22 domain family, member 2
TTLL7 tubulin tyrosine ligase-like family member 7
TYMP thymidine phosphorylase
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UNC45A unc-45 homolog A (C. elegans)
ZNF276 zinc finger protein 276
ZNF407 zinc finger protein 407
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABHD14A abhydrolase domain containing 14A
ARG1 arginase 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAMBI BMP and activin membrane-bound inhibitor
BTBD2 BTB (POZ) domain containing 2
C11ORF95 chromosome 11 open reading frame 95
C1ORF159 chromosome 1 open reading frame 159
C5ORF45 chromosome 5 open reading frame 45
CA5BP1 carbonic anhydrase VB pseudogene 1
CD151 CD151 molecule (Raph blood group)
CD180 CD180 molecule
CDCP1 CUB domain containing protein 1
CHPF chondroitin polymerizing factor
CLEC4E C-type lectin domain family 4, member E
CNTLN centlein, centrosomal protein
CNTN1 contactin 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNMBP dynamin binding protein
EPHA4 EPH receptor A4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOC6B exocyst complex component 6B
FAM222B family with sequence similarity 222, member B
FBXO46 F-box protein 46
FGF9 fibroblast growth factor 9
FKBP2 FK506 binding protein 2, 13kDa
FKBP9 FK506 binding protein 9, 63 kDa
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GAA glucosidase, alpha; acid
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GEM GTP binding protein overexpressed in skeletal muscle
GPR3 G protein-coupled receptor 3
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H1B histone cluster 1, H1b
HIST1H3B histone cluster 1, H3b
IGLV1-44 immunoglobulin lambda variable 1-44
IL11RA interleukin 11 receptor, alpha
IRX5 iroquois homeobox 5
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KRT8P12 keratin 8 pseudogene 12
LATS1 large tumor suppressor kinase 1
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LIMD2 LIM domain containing 2
LINC00216 long intergenic non-protein coding RNA 216
LOC100286895 cell division cycle 27 homolog pseudogene
MED31 mediator complex subunit 31
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MLPH melanophilin
MRPL28 mitochondrial ribosomal protein L28
MRPS18C mitochondrial ribosomal protein S18C
MUM1 melanoma associated antigen (mutated) 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NFE2L3 nuclear factor, erythroid 2-like 3
OXTR oxytocin receptor
PDE12 phosphodiesterase 12
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCD1 phospholipase C, delta 1
PLCL1 phospholipase C-like 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PNOC prepronociceptin
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
RNF31 ring finger protein 31
SALL2 spalt-like transcription factor 2
SCAMP4 secretory carrier membrane protein 4
SCGB2A2 secretoglobin, family 2A, member 2
SCML1 sex comb on midleg-like 1 (Drosophila)
SHPK sedoheptulokinase
SLC10A3 solute carrier family 10, member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPAG4 sperm associated antigen 4
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TAS2R4 taste receptor, type 2, member 4
TGFBR3 transforming growth factor, beta receptor III
TMEM212 transmembrane protein 212
TOR4A torsin family 4, member A
TRAF1 TNF receptor-associated factor 1
TRAIP TRAF interacting protein
TRPS1 trichorhinophalangeal syndrome I
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN13 tetraspanin 13
TTC23 tetratricopeptide repeat domain 23
TTC26 tetratricopeptide repeat domain 26
TUBA3C tubulin, alpha 3c
TWSG1 twisted gastrulation BMP signaling modulator 1
UBTD1 ubiquitin domain containing 1
ULK1 unc-51 like autophagy activating kinase 1
WNT16 wingless-type MMTV integration site family, member 16
ZBTB38 zinc finger and BTB domain containing 38
ZC3H12A zinc finger CCCH-type containing 12A
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF280B zinc finger protein 280B
ZNF528 zinc finger protein 528
ZNF574 zinc finger protein 574
ZNF778 zinc finger protein 778
ZNF85 zinc finger protein 85