enilconazole-5538 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the enilconazole-5538 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACTN2 actinin, alpha 2
ADAM22 ADAM metallopeptidase domain 22
ADAM8 ADAM metallopeptidase domain 8
AJAP1 adherens junctions associated protein 1
APC adenomatous polyposis coli
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASTN1 astrotactin 1
ATF6B activating transcription factor 6 beta
BATF3 basic leucine zipper transcription factor, ATF-like 3
BBS9 Bardet-Biedl syndrome 9
BMP1 bone morphogenetic protein 1
CEP164 centrosomal protein 164kDa
CHRD chordin
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLDN17 claudin 17
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DIO2 deiodinase, iodothyronine, type II
DNALI1 dynein, axonemal, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHX2 epoxide hydrolase 2, cytoplasmic
ERC1 ELKS/RAB6-interacting/CAST family member 1
FGF9 fibroblast growth factor 9
FGFR4 fibroblast growth factor receptor 4
FHL1 four and a half LIM domains 1
GAL galanin/GMAP prepropeptide
GALK1 galactokinase 1
GPR137 G protein-coupled receptor 137
GPR87 G protein-coupled receptor 87
GRM8 glutamate receptor, metabotropic 8
GSTA4 glutathione S-transferase alpha 4
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H1E histone cluster 1, H1e
HPS4 Hermansky-Pudlak syndrome 4
IRS2 insulin receptor substrate 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KEL Kell blood group, metallo-endopeptidase
KIAA0125 KIAA0125
LPCAT4 lysophosphatidylcholine acyltransferase 4
LTBP2 latent transforming growth factor beta binding protein 2
LUZP1 leucine zipper protein 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED25 mediator complex subunit 25
MMP26 matrix metallopeptidase 26
MOGAT2 monoacylglycerol O-acyltransferase 2
MX1 MX dynamin-like GTPase 1
MYO9B myosin IXB
NBEAL2 neurobeachin-like 2
NEUROD4 neuronal differentiation 4
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDPN podoplanin
PEX10 peroxisomal biogenesis factor 10
PHEX phosphate regulating endopeptidase homolog, X-linked
PITX1 paired-like homeodomain 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POFUT1 protein O-fucosyltransferase 1
PRLR prolactin receptor
PSG3 pregnancy specific beta-1-glycoprotein 3
PSG9 pregnancy specific beta-1-glycoprotein 9
QKI QKI, KH domain containing, RNA binding
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RPL7 ribosomal protein L7
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RS1 retinoschisin 1
RUFY3 RUN and FYVE domain containing 3
SCGB1D1 secretoglobin, family 1D, member 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEZ6L seizure related 6 homolog (mouse)-like
SH3BP2 SH3-domain binding protein 2
SIRT3 sirtuin 3
SLAMF8 SLAM family member 8
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX15 SRY (sex determining region Y)-box 15
SPATA1 spermatogenesis associated 1
STIM1 stromal interaction molecule 1
TAOK2 TAO kinase 2
TBC1D22A TBC1 domain family, member 22A
TCP11L1 t-complex 11, testis-specific-like 1
TET3 tet methylcytosine dioxygenase 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMEM259 transmembrane protein 259
TMEM63A transmembrane protein 63A
TTLL1 tubulin tyrosine ligase-like family member 1
TTLL3 tubulin tyrosine ligase-like family member 3
UNC119 unc-119 homolog (C. elegans)
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VIM vimentin
ZFPL1 zinc finger protein-like 1

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARID4A AT rich interactive domain 4A (RBP1-like)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AXIN1 axin 1
BAHCC1 BAH domain and coiled-coil containing 1
BAK1 BCL2-antagonist/killer 1
BIRC7 baculoviral IAP repeat containing 7
CALCOCO1 calcium binding and coiled-coil domain 1
CCNJ cyclin J
CCNL2 cyclin L2
CENPO centromere protein O
CHST10 carbohydrate sulfotransferase 10
CNR2 cannabinoid receptor 2 (macrophage)
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CTNNBIP1 catenin, beta interacting protein 1
CXADR coxsackie virus and adenovirus receptor
DCTN4 dynactin 4 (p62)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EDAR ectodysplasin A receptor
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EML4 echinoderm microtubule associated protein like 4
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLCN folliculin
FMO4 flavin containing monooxygenase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAN gigaxonin
GFOD1 glucose-fructose oxidoreductase domain containing 1
GPATCH2L G patch domain containing 2-like
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2AL histone cluster 1, H2al
HIST1H2BI histone cluster 1, H2bi
HIST1H2BJ histone cluster 1, H2bj
HPSE heparanase
IFNAR1 interferon (alpha, beta and omega) receptor 1
ITPKC inositol-trisphosphate 3-kinase C
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM5C lysine (K)-specific demethylase 5C
KIAA0753 KIAA0753
KIF18A kinesin family member 18A
KLF11 Kruppel-like factor 11
KLK5 kallikrein-related peptidase 5
KREMEN2 kringle containing transmembrane protein 2
KRI1 KRI1 homolog (S. cerevisiae)
LPXN leupaxin
LRP5 low density lipoprotein receptor-related protein 5
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC20 leucine rich repeat containing 20
LZTR1 leucine-zipper-like transcription regulator 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP9 microtubule-associated protein 9
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MFSD11 major facilitator superfamily domain containing 11
MSI1 musashi RNA-binding protein 1
MTMR12 myotubularin related protein 12
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NHEJ1 nonhomologous end-joining factor 1
NPFFR1 neuropeptide FF receptor 1
NPY5R neuropeptide Y receptor Y5
OPN3 opsin 3
PADI1 peptidyl arginine deiminase, type I
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
RFTN1 raftlin, lipid raft linker 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPL23AP32 ribosomal protein L23a pseudogene 32
RWDD3 RWD domain containing 3
SCAI suppressor of cancer cell invasion
SCAMP4 secretory carrier membrane protein 4
SCGB2A2 secretoglobin, family 2A, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SETMAR SET domain and mariner transposase fusion gene
SIRT6 sirtuin 6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SNHG20 small nucleolar RNA host gene 20
SP140L SP140 nuclear body protein-like
SPIDR scaffolding protein involved in DNA repair
SPINT1 serine peptidase inhibitor, Kunitz type 1
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
TMEM45A transmembrane protein 45A
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USP21 ubiquitin specific peptidase 21
VAV1 vav 1 guanine nucleotide exchange factor
VAX2 ventral anterior homeobox 2
VGF VGF nerve growth factor inducible
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF205 zinc finger protein 205
ZNF442 zinc finger protein 442
ZNF571 zinc finger protein 571
ZNF8 zinc finger protein 8
ZSCAN31 zinc finger and SCAN domain containing 31