enlarged pancreatic islets Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the size of the clusters of hormone-producing cells that are scattered throughout the pancreas (Mammalian Phenotype Ontology, MP_0009171)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009171
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39 gene mutations causing the enlarged pancreatic islets phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALMS1 Alstrom syndrome protein 1
ANXA7 annexin A7
ATXN2 ataxin 2
BRD2 bromodomain containing 2
CCDC80 coiled-coil domain containing 80
CPE carboxypeptidase E
CTF1 cardiotrophin 1
EHD4 EH-domain containing 4
ESR2 estrogen receptor 2 (ER beta)
FFAR4 free fatty acid receptor 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
GCGR glucagon receptor
GDF11 growth differentiation factor 11
INVS inversin
KMT2B lysine (K)-specific methyltransferase 2B
LEP leptin
LEPR leptin receptor
LIPE lipase, hormone-sensitive
MEN1 multiple endocrine neoplasia I
OPRM1 opioid receptor, mu 1
PAX2 paired box 2
PDPK1 3-phosphoinositide dependent protein kinase 1
PGR progesterone receptor
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PPARG peroxisome proliferator-activated receptor gamma
PRKCI protein kinase C, iota
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RIMS2 regulating synaptic membrane exocytosis 2
SCG5 secretogranin V
SH2B1 SH2B adaptor protein 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SOCS7 suppressor of cytokine signaling 7
SOX9 SRY (sex determining region Y)-box 9
THBS1 thrombospondin 1
TNK1 tyrosine kinase, non-receptor, 1
TOP3B topoisomerase (DNA) III beta
TUB tubby bipartite transcription factor