enlarged thymus Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increased size of thymus (Mammalian Phenotype Ontology, MP_0000709)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000709
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51 gene mutations causing the enlarged thymus phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADRM1 adhesion regulating molecule 1
BHLHE40 basic helix-loop-helix family, member e40
BOK BCL2-related ovarian killer
BRCA2 breast cancer 2, early onset
CD28 CD28 molecule
CDK6 cyclin-dependent kinase 6
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CISH cytokine inducible SH2-containing protein
CYLD cylindromatosis (turban tumor syndrome)
E2F1 E2F transcription factor 1
ERAP1 endoplasmic reticulum aminopeptidase 1
ERRFI1 ERBB receptor feedback inhibitor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FOXN1 forkhead box N1
GADD45A growth arrest and DNA-damage-inducible, alpha
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL2RG interleukin 2 receptor, gamma
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
KISS1R KISS1 receptor
KLF13 Kruppel-like factor 13
LCN2 lipocalin 2
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
PIP prolactin-induced protein
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PTEN phosphatase and tensin homolog
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTTG1 pituitary tumor-transforming 1
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RUNX2 runt-related transcription factor 2
SAC3D1 SAC3 domain containing 1
SELENBP1 selenium binding protein 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SOAT1 sterol O-acyltransferase 1
STK4 serine/threonine kinase 4
TBATA thymus, brain and testes associated
TCF3 transcription factor 3
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UNG uracil-DNA glycosylase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor