enoxacin-1597 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the enoxacin-1597 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADK adenosine kinase
ALAD aminolevulinate dehydratase
ANKRD12 ankyrin repeat domain 12
APP amyloid beta (A4) precursor protein
ATP11B ATPase, class VI, type 11B
ATP9B ATPase, class II, type 9B
ATXN7 ataxin 7
AZI2 5-azacytidine induced 2
BBS10 Bardet-Biedl syndrome 10
CAST calpastatin
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CD164 CD164 molecule, sialomucin
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDCA3 cell division cycle associated 3
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CS citrate synthase
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CYB5A cytochrome b5 type A (microsomal)
DENND4A DENN/MADD domain containing 4A
DPYD dihydropyrimidine dehydrogenase
EID1 EP300 interacting inhibitor of differentiation 1
ERAP1 endoplasmic reticulum aminopeptidase 1
FAM188A family with sequence similarity 188, member A
FAM63A family with sequence similarity 63, member A
FN1 fibronectin 1
FSCN3 fascin actin-bundling protein 3, testicular
GIMAP5 GTPase, IMAP family member 5
GPR183 G protein-coupled receptor 183
HIRA histone cell cycle regulator
IDS iduronate 2-sulfatase
IRAK3 interleukin-1 receptor-associated kinase 3
ITM2B integral membrane protein 2B
JUN jun proto-oncogene
KDM6A lysine (K)-specific demethylase 6A
KIFC1 kinesin family member C1
KLHL20 kelch-like family member 20
KLHL7 kelch-like family member 7
KTN1 kinectin 1 (kinesin receptor)
LAMP2 lysosomal-associated membrane protein 2
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP12 low density lipoprotein receptor-related protein 12
LUC7L3 LUC7-like 3 (S. cerevisiae)
MCTP1 multiple C2 domains, transmembrane 1
MTMR6 myotubularin related protein 6
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NBPF10 neuroblastoma breakpoint family, member 10
NDRG2 NDRG family member 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
OGFRL1 opioid growth factor receptor-like 1
PAM peptidylglycine alpha-amidating monooxygenase
PAPOLG poly(A) polymerase gamma
PAQR3 progestin and adipoQ receptor family member III
PDE3B phosphodiesterase 3B, cGMP-inhibited
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLA2G12A phospholipase A2, group XIIA
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RABGGTB Rab geranylgeranyltransferase, beta subunit
RALB v-ral simian leukemia viral oncogene homolog B
REL v-rel avian reticuloendotheliosis viral oncogene homolog
REST RE1-silencing transcription factor
RGS1 regulator of G-protein signaling 1
RIOK3 RIO kinase 3
RNF170 ring finger protein 170
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL7 ribosomal protein L7
RPS2 ribosomal protein S2
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RWDD3 RWD domain containing 3
SCAF4 SR-related CTD-associated factor 4
SEC23B Sec23 homolog B (S. cerevisiae)
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SMAD7 SMAD family member 7
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMC2 structural maintenance of chromosomes 2
SNX11 sorting nexin 11
SOAT1 sterol O-acyltransferase 1
SOD2 superoxide dismutase 2, mitochondrial
TANK TRAF family member-associated NFKB activator
TK2 thymidine kinase 2, mitochondrial
TLK2 tousled-like kinase 2
TMED7 transmembrane emp24 protein transport domain containing 7
TTC37 tetratricopeptide repeat domain 37
UBE2D1 ubiquitin-conjugating enzyme E2D 1
WASF1 WAS protein family, member 1
WSB1 WD repeat and SOCS box containing 1
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZBTB22 zinc finger and BTB domain containing 22
ZFX zinc finger protein, X-linked
ZNF142 zinc finger protein 142
ZNF217 zinc finger protein 217
ZNF518A zinc finger protein 518A
ZNF83 zinc finger protein 83

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACVR2A activin A receptor, type IIA
ADAT1 adenosine deaminase, tRNA-specific 1
ADGRA3 adhesion G protein-coupled receptor A3
APOBR apolipoprotein B receptor
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGAP11A Rho GTPase activating protein 11A
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ASB13 ankyrin repeat and SOCS box containing 13
ATAD2B ATPase family, AAA domain containing 2B
ATAT1 alpha tubulin acetyltransferase 1
ATG2A autophagy related 2A
ATG4A autophagy related 4A, cysteine peptidase
BCL7B B-cell CLL/lymphoma 7B
BCL7C B-cell CLL/lymphoma 7C
C4ORF29 chromosome 4 open reading frame 29
C6ORF47 chromosome 6 open reading frame 47
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD151 CD151 molecule (Raph blood group)
CEP170B centrosomal protein 170B
CEP70 centrosomal protein 70kDa
CER1 cerberus 1, DAN family BMP antagonist
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST10 carbohydrate sulfotransferase 10
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CST3 cystatin C
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DRD5 dopamine receptor D5
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EPX eosinophil peroxidase
EXD2 exonuclease 3'-5' domain containing 2
FAM168B family with sequence similarity 168, member B
FAM50B family with sequence similarity 50, member B
FICD FIC domain containing
FMO4 flavin containing monooxygenase 4
FOS FBJ murine osteosarcoma viral oncogene homolog
GGTLC1 gamma-glutamyltransferase light chain 1
GPR27 G protein-coupled receptor 27
GRPR gastrin-releasing peptide receptor
GSS glutathione synthetase
GTPBP6 GTP binding protein 6 (putative)
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IL2RB interleukin 2 receptor, beta
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRT38 keratin 38, type I
LCT lactase
LINC00312 long intergenic non-protein coding RNA 312
LMAN2L lectin, mannose-binding 2-like
LTB lymphotoxin beta (TNF superfamily, member 3)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MBTD1 mbt domain containing 1
MCC mutated in colorectal cancers
MOGS mannosyl-oligosaccharide glucosidase
MPI mannose phosphate isomerase
MRPS34 mitochondrial ribosomal protein S34
MX1 MX dynamin-like GTPase 1
MXRA8 matrix-remodelling associated 8
NHEJ1 nonhomologous end-joining factor 1
NPDC1 neural proliferation, differentiation and control, 1
NUP93 nucleoporin 93kDa
NXT1 nuclear transport factor 2-like export factor 1
OR2C1 olfactory receptor, family 2, subfamily C, member 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PADI1 peptidyl arginine deiminase, type I
PCDHGB5 protocadherin gamma subfamily B, 5
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPIEL peptidylprolyl isomerase E-like pseudogene
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RWDD2B RWD domain containing 2B
SASH3 SAM and SH3 domain containing 3
SDF2L1 stromal cell-derived factor 2-like 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SPX spexin hormone
SRRD SRR1 domain containing
STARD8 StAR-related lipid transfer (START) domain containing 8
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
THAP7 THAP domain containing 7
TPCN1 two pore segment channel 1
TRAPPC12 trafficking protein particle complex 12
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TUBA3C tubulin, alpha 3c
TUBB3 tubulin, beta 3 class III
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UNC13B unc-13 homolog B (C. elegans)
USB1 U6 snRNA biogenesis 1
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
XDH xanthine dehydrogenase
ZC3H3 zinc finger CCCH-type containing 3
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF529 zinc finger protein 529
ZNF768 zinc finger protein 768