enoxacin-4655 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the enoxacin-4655 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARTN artemin
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
B3GAT1 beta-1,3-glucuronyltransferase 1
BST1 bone marrow stromal cell antigen 1
CARD10 caspase recruitment domain family, member 10
CD1C CD1c molecule
CDC42 cell division cycle 42
CHIA chitinase, acidic
COL14A1 collagen, type XIV, alpha 1
COL9A3 collagen, type IX, alpha 3
CPEB3 cytoplasmic polyadenylation element binding protein 3
CSF1R colony stimulating factor 1 receptor
CST4 cystatin S
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
DCX doublecortin
DMPK dystrophia myotonica-protein kinase
DPYSL4 dihydropyrimidinase-like 4
DRP2 dystrophin related protein 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERAP1 endoplasmic reticulum aminopeptidase 1
EXOSC2 exosome component 2
FAM63A family with sequence similarity 63, member A
FBRS fibrosin
FCAR Fc fragment of IgA receptor
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FLJ22184
FLT4 fms-related tyrosine kinase 4
FMOD fibromodulin
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GADD45G growth arrest and DNA-damage-inducible, gamma
GLRA1 glycine receptor, alpha 1
GPR75 G protein-coupled receptor 75
HABP4 hyaluronan binding protein 4
HCRP1 hepatocellular carcinoma-related HCRP1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOOK1 hook microtubule-tethering protein 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IBSP integrin-binding sialoprotein
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
INSR insulin receptor
JAG1 jagged 1
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
LEF1 lymphoid enhancer-binding factor 1
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LOC100294391 uncharacterized LOC100294391
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MCTP2 multiple C2 domains, transmembrane 2
MEF2D myocyte enhancer factor 2D
MYL10 myosin, light chain 10, regulatory
NCR1 natural cytotoxicity triggering receptor 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR4A2 nuclear receptor subfamily 4, group A, member 2
ONECUT2 one cut homeobox 2
PAPPA2 pappalysin 2
PCDHB3 protocadherin beta 3
PCSK6 proprotein convertase subtilisin/kexin type 6
PI3 peptidase inhibitor 3, skin-derived
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLA2G3 phospholipase A2, group III
PML promyelocytic leukemia
PRDM12 PR domain containing 12
PRDM14 PR domain containing 14
PTGDS prostaglandin D2 synthase 21kDa (brain)
PVT1 Pvt1 oncogene (non-protein coding)
RAB2A RAB2A, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RFXAP regulatory factor X-associated protein
RPL35A ribosomal protein L35a
RPS4Y1 ribosomal protein S4, Y-linked 1
SARM1 sterile alpha and TIR motif containing 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEPP1 selenoprotein P, plasma, 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLMO1 slowmo homolog 1 (Drosophila)
SMAD5-AS1 SMAD5 antisense RNA 1
SOS2 son of sevenless homolog 2 (Drosophila)
SSTR2 somatostatin receptor 2
SUGP1 SURP and G patch domain containing 1
SULF1 sulfatase 1
TAOK1 TAO kinase 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRIM29 tripartite motif containing 29
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VASH1 vasohibin 1
VGLL1 vestigial-like family member 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WSB1 WD repeat and SOCS box containing 1
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF334 zinc finger protein 334

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACP2 acid phosphatase 2, lysosomal
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKRD40 ankyrin repeat domain 40
AUH AU RNA binding protein/enoyl-CoA hydratase
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHD1 bromo adjacent homology domain containing 1
BEX1 brain expressed, X-linked 1
C11ORF63 chromosome 11 open reading frame 63
C14ORF105 chromosome 14 open reading frame 105
C14ORF79 chromosome 14 open reading frame 79
C1QTNF1 C1q and tumor necrosis factor related protein 1
CAMKMT calmodulin-lysine N-methyltransferase
CIDEC cell death-inducing DFFA-like effector c
CINP cyclin-dependent kinase 2 interacting protein
CIR1 corepressor interacting with RBPJ, 1
CLDN15 claudin 15
CNTNAP1 contactin associated protein 1
COQ4 coenzyme Q4
CPZ carboxypeptidase Z
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYBRD1 cytochrome b reductase 1
DEPTOR DEP domain containing MTOR-interacting protein
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EHF ets homologous factor
ERCC2 excision repair cross-complementation group 2
FAM188A family with sequence similarity 188, member A
FBXL7 F-box and leucine-rich repeat protein 7
FMO4 flavin containing monooxygenase 4
FUZ fuzzy planar cell polarity protein
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GPR27 G protein-coupled receptor 27
GTF2I general transcription factor IIi
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
H2AFJ H2A histone family, member J
HDAC7 histone deacetylase 7
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2BO histone cluster 1, H2bo
HSPA1L heat shock 70kDa protein 1-like
IL6 interleukin 6
KLHL25 kelch-like family member 25
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT20 keratin 20, type I
LAMC3 laminin, gamma 3
LIG4 ligase IV, DNA, ATP-dependent
LIME1 Lck interacting transmembrane adaptor 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTC4S leukotriene C4 synthase
MANBA mannosidase, beta A, lysosomal
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MFSD6 major facilitator superfamily domain containing 6
MOCS3 molybdenum cofactor synthesis 3
MYH15 myosin, heavy chain 15
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
NTF3 neurotrophin 3
NUPR1 nuclear protein, transcriptional regulator, 1
PCDH12 protocadherin 12
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGPEP1 pyroglutamyl-peptidase I
PID1 phosphotyrosine interaction domain containing 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PTK6 protein tyrosine kinase 6
R3HCC1L R3H domain and coiled-coil containing 1-like
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RSL24D1 ribosomal L24 domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC25A40 solute carrier family 25, member 40
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMR3A submaxillary gland androgen regulated protein 3A
SPATA2L spermatogenesis associated 2-like
SPINK1 serine peptidase inhibitor, Kazal type 1
SPTBN2 spectrin, beta, non-erythrocytic 2
STAB2 stabilin 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP4 STEAP family member 4
STK16 serine/threonine kinase 16
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBX19 T-box 19
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM183A transmembrane protein 183A
TMEM212 transmembrane protein 212
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNRC6B trinucleotide repeat containing 6B
TRAPPC13 trafficking protein particle complex 13
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TUBA4B tubulin, alpha 4b
WNT10B wingless-type MMTV integration site family, member 10B
ZBTB22 zinc finger and BTB domain containing 22
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF205 zinc finger protein 205
ZNF230 zinc finger protein 230
ZNF778 zinc finger protein 778
ZNF816 zinc finger protein 816