| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the enoxacin-5251 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AK1 | adenylate kinase 1 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| ANO1 | anoctamin 1, calcium activated chloride channel |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| AQP7 | aquaporin 7 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CACNG3 | calcium channel, voltage-dependent, gamma subunit 3 |
| CD58 | CD58 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDK13 | cyclin-dependent kinase 13 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHI3L2 | chitinase 3-like 2 |
| CLCA2 | chloride channel accessory 2 |
| CLTA | clathrin, light chain A |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CPM | carboxypeptidase M |
| CRH | corticotropin releasing hormone |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP3A7 | cytochrome P450, family 3, subfamily A, polypeptide 7 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DCTN1 | dynactin 1 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DMXL2 | Dmx-like 2 |
| EGR1 | early growth response 1 |
| EXOC7 | exocyst complex component 7 |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 |
| FBLN1 | fibulin 1 |
| FGF16 | fibroblast growth factor 16 |
| FHL1 | four and a half LIM domains 1 |
| FOXG1 | forkhead box G1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GARNL3 | GTPase activating Rap/RanGAP domain-like 3 |
| GPR137 | G protein-coupled receptor 137 |
| GPR143 | G protein-coupled receptor 143 |
| GYPB | glycophorin B (MNS blood group) |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HFE | hemochromatosis |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL16 | interleukin 16 |
| IL1A | interleukin 1, alpha |
| ING2 | inhibitor of growth family, member 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JUN | jun proto-oncogene |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MVB12B | multivesicular body subunit 12B |
| NF1 | neurofibromin 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| ONECUT2 | one cut homeobox 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PARVA | parvin, alpha |
| PCDH7 | protocadherin 7 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| POLM | polymerase (DNA directed), mu |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RAB6B | RAB6B, member RAS oncogene family |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| REEP2 | receptor accessory protein 2 |
| RND2 | Rho family GTPase 2 |
| RPL35A | ribosomal protein L35a |
| SHOX2 | short stature homeobox 2 |
| SLAMF7 | SLAM family member 7 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TNS1 | tensin 1 |
| UPK3B | uroplakin 3B |
| VN1R1 | vomeronasal 1 receptor 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZNF407 | zinc finger protein 407 |
| ZNF440 | zinc finger protein 440 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACTL8 | actin-like 8 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ALS2CL | ALS2 C-terminal like |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMC6 | armadillo repeat containing 6 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BLNK | B-cell linker |
| BMP15 | bone morphogenetic protein 15 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CENPO | centromere protein O |
| CERK | ceramide kinase |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN15 | claudin 15 |
| CLGN | calmegin |
| CLSTN2 | calsyntenin 2 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORT | cortistatin |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EDAR | ectodysplasin A receptor |
| EFNA3 | ephrin-A3 |
| ERCC5 | excision repair cross-complementation group 5 |
| FGL1 | fibrinogen-like 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAS2 | growth arrest-specific 2 |
| GID4 | GID complex subunit 4 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR21 | G protein-coupled receptor 21 |
| GPR27 | G protein-coupled receptor 27 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KIAA0754 | KIAA0754 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LMNB1 | lamin B1 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MATK | megakaryocyte-associated tyrosine kinase |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MGC12488 | |
| MPI | mannose phosphate isomerase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MUC3A | mucin 3A, cell surface associated |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPFFR1 | neuropeptide FF receptor 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OVOL1 | ovo-like zinc finger 1 |
| PCDHB13 | protocadherin beta 13 |
| PGR | progesterone receptor |
| PGS1 | phosphatidylglycerophosphate synthase 1 |
| PLA2G10 | phospholipase A2, group X |
| PLA2G3 | phospholipase A2, group III |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PRSS16 | protease, serine, 16 (thymus) |
| PRSS53 | protease, serine, 53 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RNF43 | ring finger protein 43 |
| RPGRIP1L | RPGRIP1-like |
| RPL10L | ribosomal protein L10-like |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| S100A7 | S100 calcium binding protein A7 |
| S100A9 | S100 calcium binding protein A9 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLPI | secretory leukocyte peptidase inhibitor |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STK16 | serine/threonine kinase 16 |
| STK25 | serine/threonine kinase 25 |
| STON1 | stonin 1 |
| STRA6 | stimulated by retinoic acid 6 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TCTA | T-cell leukemia translocation altered |
| TCTN1 | tectonic family member 1 |
| TMEM120B | transmembrane protein 120B |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRIM36 | tripartite motif containing 36 |
| TUBG2 | tubulin, gamma 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VPS9D1 | VPS9 domain containing 1 |
| ZIC3 | Zic family member 3 |
| ZNF324 | zinc finger protein 324 |
| ZNF639 | zinc finger protein 639 |
| ZNF816 | zinc finger protein 816 |
| ZNF862 | zinc finger protein 862 |