| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the enoxacin-5616 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAMTS8 | ADAM metallopeptidase with thrombospondin type 1 motif, 8 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ART1 | ADP-ribosyltransferase 1 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| BTG2 | BTG family, member 2 |
| CALD1 | caldesmon 1 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) |
| CERS4 | ceramide synthase 4 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 |
| COL6A2 | collagen, type VI, alpha 2 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CST4 | cystatin S |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DCTN1 | dynactin 1 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DGCR14 | DiGeorge syndrome critical region gene 14 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| EDNRA | endothelin receptor type A |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
| EVA1B | eva-1 homolog B (C. elegans) |
| EXTL1 | exostosin-like glycosyltransferase 1 |
| FBLN1 | fibulin 1 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GFAP | glial fibrillary acidic protein |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GOLGA8A | golgin A8 family, member A |
| GPR85 | G protein-coupled receptor 85 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
| HIST1H3I | histone cluster 1, H3i |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HOPX | HOP homeobox |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IL11 | interleukin 11 |
| IL11RA | interleukin 11 receptor, alpha |
| IQCA1 | IQ motif containing with AAA domain 1 |
| IRS4 | insulin receptor substrate 4 |
| ITGB5 | integrin, beta 5 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KIF5A | kinesin family member 5A |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LDHB | lactate dehydrogenase B |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LRRN2 | leucine rich repeat neuronal 2 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAG | myelin associated glycoprotein |
| MAPK8 | mitogen-activated protein kinase 8 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MCAM | melanoma cell adhesion molecule |
| MEOX1 | mesenchyme homeobox 1 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MPZ | myelin protein zero |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NRL | neural retina leucine zipper |
| NUP188 | nucleoporin 188kDa |
| PCDH9 | protocadherin 9 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLAU | plasminogen activator, urokinase |
| PNLIPRP1 | pancreatic lipase-related protein 1 |
| PRLH | prolactin releasing hormone |
| PTAFR | platelet-activating factor receptor |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RNF122 | ring finger protein 122 |
| RPS3A | ribosomal protein S3A |
| RS1 | retinoschisin 1 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIRT5 | sirtuin 5 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SRPK2 | SRSF protein kinase 2 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STK11 | serine/threonine kinase 11 |
| SYN2 | synapsin II |
| TMEM63A | transmembrane protein 63A |
| TSPY1 | testis specific protein, Y-linked 1 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| USP22 | ubiquitin specific peptidase 22 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF3 | zinc finger protein 3 |
| ZNF646 | zinc finger protein 646 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALOX15 | arachidonate 15-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| ALS2CL | ALS2 C-terminal like |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOD | apolipoprotein D |
| ARMC6 | armadillo repeat containing 6 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CPNE7 | copine VII |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CST6 | cystatin E/M |
| CSTA | cystatin A (stefin A) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DOCK1 | dedicator of cytokinesis 1 |
| DRD1 | dopamine receptor D1 |
| DVL1 | dishevelled segment polarity protein 1 |
| EFNA3 | ephrin-A3 |
| ELMO3 | engulfment and cell motility 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM110B | family with sequence similarity 110, member B |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FFAR2 | free fatty acid receptor 2 |
| FGF23 | fibroblast growth factor 23 |
| GAA | glucosidase, alpha; acid |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GRPR | gastrin-releasing peptide receptor |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HOXA4 | homeobox A4 |
| HYI | hydroxypyruvate isomerase (putative) |
| IFT140 | intraflagellar transport 140 |
| IL17RA | interleukin 17 receptor A |
| INO80D | INO80 complex subunit D |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0319L | KIAA0319-like |
| KLF2 | Kruppel-like factor 2 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MTA2 | metastasis associated 1 family, member 2 |
| MYO1F | myosin IF |
| NME5 | NME/NM23 family member 5 |
| NPTX1 | neuronal pentraxin I |
| NRSN2 | neurensin 2 |
| OLFML2A | olfactomedin-like 2A |
| PADI1 | peptidyl arginine deiminase, type I |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PRODH | proline dehydrogenase (oxidase) 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RIN1 | Ras and Rab interactor 1 |
| S100A9 | S100 calcium binding protein A9 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SMIM14 | small integral membrane protein 14 |
| TBX19 | T-box 19 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TNS2 | tensin 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| UPK3B | uroplakin 3B |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VASH1 | vasohibin 1 |
| WWC2 | WW and C2 domain containing 2 |
| XAB2 | XPA binding protein 2 |
| YEATS2 | YEATS domain containing 2 |
| ZNF134 | zinc finger protein 134 |
| ZNF16 | zinc finger protein 16 |
| ZNF219 | zinc finger protein 219 |
| ZNF573 | zinc finger protein 573 |
| ZNF701 | zinc finger protein 701 |
