enriched Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

263 genes co-occuring with the biological term enriched in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABI1 abl-interactor 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADAM17 ADAM metallopeptidase domain 17
ADAM33 ADAM metallopeptidase domain 33
ADAP1 ArfGAP with dual PH domains 1
ADGRE5 adhesion G protein-coupled receptor E5
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA1 annexin A1
ANXA6 annexin A6
APC adenomatous polyposis coli
APOC1 apolipoprotein C-I
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ASF1A anti-silencing function 1A histone chaperone
ASTN2 astrotactin 2
ATF6 activating transcription factor 6
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATXN7 ataxin 7
BATF basic leucine zipper transcription factor, ATF-like
BAX BCL2-associated X protein
BCR breakpoint cluster region
BECN1 beclin 1, autophagy related
BHLHA15 basic helix-loop-helix family, member a15
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP7 bone morphogenetic protein 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
C19ORF80 chromosome 19 open reading frame 80
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAPN10 calpain 10
CAV1 caveolin 1, caveolae protein, 22kDa
CBX1 chromobox homolog 1
CCL2 chemokine (C-C motif) ligand 2
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCNE2 cyclin E2
CCNT1 cyclin T1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR8 chemokine (C-C motif) receptor 8
CD19 CD19 molecule
CD1D CD1d molecule
CD38 CD38 molecule
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CD47 CD47 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CELF1 CUGBP, Elav-like family member 1
CETP cholesteryl ester transfer protein, plasma
CFH complement factor H
CGB7 chorionic gonadotropin, beta polypeptide 7
CLDN2 claudin 2
COL4A1 collagen, type IV, alpha 1
CREB1 cAMP responsive element binding protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYCS cytochrome c, somatic
CYR61 cysteine-rich, angiogenic inducer, 61
DICER1 dicer 1, ribonuclease type III
DISC1 disrupted in schizophrenia 1
DTNBP1 dystrobrevin binding protein 1
DYSF dysferlin
E2F1 E2F transcription factor 1
E2F4 E2F transcription factor 4, p107/p130-binding
EGFR epidermal growth factor receptor
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPCAM epithelial cell adhesion molecule
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EXOC1 exocyst complex component 1
EZR ezrin
FANCC Fanconi anemia, complementation group C
FBXO25 F-box protein 25
FBXO32 F-box protein 32
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FGFR2 fibroblast growth factor receptor 2
FMR1 fragile X mental retardation 1
FOXA1 forkhead box A1
FOXA2 forkhead box A2
FOXG1 forkhead box G1
FOXL2 forkhead box L2
FOXP3 forkhead box P3
GDF15 growth differentiation factor 15
GJD2 gap junction protein, delta 2, 36kDa
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GNLY granulysin
H2AFX H2A histone family, member X
H2AFY H2A histone family, member Y
H2AFZ H2A histone family, member Z
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HDAC9 histone deacetylase 9
HES6 hes family bHLH transcription factor 6
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1C histone cluster 1, H1c
HIST1H1E histone cluster 1, H1e
HIST3H3 histone cluster 3, H3
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
ICAM1 intercellular adhesion molecule 1
ICAM3 intercellular adhesion molecule 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNG interferon, gamma
IKZF2 IKAROS family zinc finger 2 (Helios)
IL15 interleukin 15
IL17A interleukin 17A
IL2 interleukin 2
IL22 interleukin 22
IL2RA interleukin 2 receptor, alpha
IL6 interleukin 6
IL6R interleukin 6 receptor
IL9 interleukin 9
INPP5K inositol polyphosphate-5-phosphatase K
IRF1 interferon regulatory factor 1
IRF7 interferon regulatory factor 7
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA6 integrin, alpha 6
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KAT2A K(lysine) acetyltransferase 2A
KAT6A K(lysine) acetyltransferase 6A
KAT6B K(lysine) acetyltransferase 6B
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2
KIF1B kinesin family member 1B
KIF3A kinesin family member 3A
KLF2 Kruppel-like factor 2
KMT2A lysine (K)-specific methyltransferase 2A
KMT2D lysine (K)-specific methyltransferase 2D
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT5 keratin 5, type II
KTN1 kinectin 1 (kinesin receptor)
LAMP1 lysosomal-associated membrane protein 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIMK1 LIM domain kinase 1
LMTK2 lemur tyrosine kinase 2
LPXN leupaxin
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
MBD2 methyl-CpG binding domain protein 2
MBD3 methyl-CpG binding domain protein 3
MECP2 methyl CpG binding protein 2
MED1 mediator complex subunit 1
MEF2C myocyte enhancer factor 2C
MGARP mitochondria-localized glutamic acid-rich protein
MGLL monoglyceride lipase
MIR126 microRNA 126
MIR143 microRNA 143
MIR145 microRNA 145
MIR155 microRNA 155
MIR21 microRNA 21
MIR34A microRNA 34a
MITF microphthalmia-associated transcription factor
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MRPL46 mitochondrial ribosomal protein L46
MUTYH mutY homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
NES nestin
NEUROD1 neuronal differentiation 1
NKRF NFKB repressing factor
NOTCH1 notch 1
NPC1L1 NPC1-like 1
NR2E1 nuclear receptor subfamily 2, group E, member 1
OTX2 orthodenticle homeobox 2
OXTR oxytocin receptor
PAX6 paired box 6
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDX1 pancreatic and duodenal homeobox 1
PEA15 phosphoprotein enriched in astrocytes 15
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCB2 phospholipase C, beta 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCB4 phospholipase C, beta 4
PLD2 phospholipase D2
PLN phospholamban
PMEL premelanosome protein
PML promyelocytic leukemia
PON1 paraoxonase 1
PON2 paraoxonase 2
POU5F1 POU class 5 homeobox 1
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C
PROM1 prominin 1
PSEN1 presenilin 1
PSEN2 presenilin 2
PTGDR2 prostaglandin D2 receptor 2
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPRC protein tyrosine phosphatase, receptor type, C
RAD51D RAD51 paralog D
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG2 recombination activating gene 2
RANBP2 RAN binding protein 2
RB1 retinoblastoma 1
RBSN rabenosyn, RAB effector
RHEB Ras homolog enriched in brain
RNF31 ring finger protein 31
SETDB1 SET domain, bifurcated 1
SIRPG signal-regulatory protein gamma
SIRT6 sirtuin 6
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLK STE20-like kinase
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SNAPIN SNAP-associated protein
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRPE small nuclear ribonucleoprotein polypeptide E
SORBS1 sorbin and SH3 domain containing 1
SORBS3 sorbin and SH3 domain containing 3
SP1 Sp1 transcription factor
SS18 synovial sarcoma translocation, chromosome 18
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
STK10 serine/threonine kinase 10
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TAS2R38 taste receptor, type 2, member 38
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDGF1 teratocarcinoma-derived growth factor 1
TERF2IP telomeric repeat binding factor 2, interacting protein
TERT telomerase reverse transcriptase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
THY1 Thy-1 cell surface antigen
TLR4 toll-like receptor 4
TMX1 thioredoxin-related transmembrane protein 1
TMX2 thioredoxin-related transmembrane protein 2
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPI1 triosephosphate isomerase 1
TREM2 triggering receptor expressed on myeloid cells 2
TRIM32 tripartite motif containing 32
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase
TTR transthyretin
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIMP VCP-interacting membrane selenoprotein
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WNT5A wingless-type MMTV integration site family, member 5A
WRAP53 WD repeat containing, antisense to TP53
ZNF423 zinc finger protein 423