enzyme-linked receptor protein signaling pathway Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0007167)
External Link http://amigo.geneontology.org/amigo/term/GO_0007167
Similar Terms
Downloads & Tools

Genes

125 genes participating in the enzyme-linked receptor protein signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ABI1 abl-interactor 1
ACVR1B activin A receptor, type IB
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
AHI1 Abelson helper integration site 1
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPTL1 angiopoietin-like 1
ART4 ADP-ribosyltransferase 4 (Dombrock blood group)
AXL AXL receptor tyrosine kinase
BCAR1 breast cancer anti-estrogen resistance 1
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
BLK BLK proto-oncogene, Src family tyrosine kinase
BLNK B-cell linker
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CASS4 Cas scaffolding protein family member 4
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD4 CD4 molecule
CD7 CD7 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CLNK cytokine-dependent hematopoietic cell linker
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
DDR1 discoidin domain receptor tyrosine kinase 1
DDR2 discoidin domain receptor tyrosine kinase 2
DOK2 docking protein 2, 56kDa
DOK3 docking protein 3
DOK4 docking protein 4
DOK5 docking protein 5
DOK6 docking protein 6
EFS embryonal Fyn-associated substrate
EGFR epidermal growth factor receptor
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
FAM150A family with sequence similarity 150, member A
FAM150B family with sequence similarity 150, member B
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FGR FGR proto-oncogene, Src family tyrosine kinase
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FRK fyn-related Src family tyrosine kinase
FRS2 fibroblast growth factor receptor substrate 2
FYN FYN proto-oncogene, Src family tyrosine kinase
GFRA2 GDNF family receptor alpha 2
GP6 glycoprotein VI (platelet)
GUCA1B guanylate cyclase activator 1B (retina)
GUCY2C guanylate cyclase 2C
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
GUCY2F guanylate cyclase 2F, retinal
HCK HCK proto-oncogene, Src family tyrosine kinase
IL31RA interleukin 31 receptor A
IL6ST interleukin 6 signal transducer
INSR insulin receptor
INSRR insulin receptor-related receptor
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KDR kinase insert domain receptor
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIF leukemia inhibitory factor
LIFR leukemia inhibitory factor receptor alpha
LRP1 low density lipoprotein receptor-related protein 1
LTK leukocyte receptor tyrosine kinase
LYN LYN proto-oncogene, Src family tyrosine kinase
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MPZL1 myelin protein zero-like 1
MST1R macrophage stimulating 1 receptor
MTSS1 metastasis suppressor 1
MUSK muscle, skeletal, receptor tyrosine kinase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NGF nerve growth factor (beta polypeptide)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPPC natriuretic peptide C
NPR1 natriuretic peptide receptor 1
NPR2 natriuretic peptide receptor 2
NTF3 neurotrophin 3
NTF4 neurotrophin 4
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDZD3 PDZ domain containing 3
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PILRB paired immunoglobin-like type 2 receptor beta
POLR1G RNA polymerase I subunit G
PTK6 protein tyrosine kinase 6
PTN pleiotrophin
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRT protein tyrosine phosphatase, receptor type, T
PTPRU protein tyrosine phosphatase, receptor type, U
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASGRP4 RAS guanyl releasing protein 4
RET ret proto-oncogene
ROR1 receptor tyrosine kinase-like orphan receptor 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RYK receptor-like tyrosine kinase
SAMD10 sterile alpha motif domain containing 10
SAMD12 sterile alpha motif domain containing 12
SH2D6 SH2 domain containing 6
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHC4 SHC (Src homology 2 domain containing) family, member 4
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
SYK spleen tyrosine kinase
TEK TEK tyrosine kinase, endothelial
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TRIO trio Rho guanine nucleotide exchange factor
TYRO3 TYRO3 protein tyrosine kinase
UXT ubiquitously-expressed, prefoldin-like chaperone
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa