eosinophilia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

372 genes co-occuring with the disease eosinophilia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
IL5 interleukin 5 2.9666
FIP1L1 factor interacting with PAPOLA and CPSF1 2.36234
RNASE3 ribonuclease, RNase A family, 3 2.13015
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.09055
CCL11 chemokine (C-C motif) ligand 11 2.0536
EPX eosinophil peroxidase 2.01705
CD4 CD4 molecule 1.9755
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.89499
FLNC filamin C, gamma 1.82142
CCR3 chemokine (C-C motif) receptor 3 1.81058
IL4 interleukin 4 1.7939
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 1.74824
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.70497
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.64173
FGFR1 fibroblast growth factor receptor 1 1.54805
CCL17 chemokine (C-C motif) ligand 17 1.5216
IL13 interleukin 13 1.45001
IL2 interleukin 2 1.44869
CCL13 chemokine (C-C motif) ligand 13 1.38821
IL3 interleukin 3 1.37905
CCL24 chemokine (C-C motif) ligand 24 1.33807
CD79A CD79a molecule, immunoglobulin-associated alpha 1.3276
PTGDR2 prostaglandin D2 receptor 2 1.30663
KIAA0101 KIAA0101 1.28086
MYH11 myosin, heavy chain 11, smooth muscle 1.27693
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.26821
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.26778
GATA3 GATA binding protein 3 1.23994
CHIC2 cysteine-rich hydrophobic domain 2 1.21998
FOXP3 forkhead box P3 1.20829
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.20742
VCAM1 vascular cell adhesion molecule 1 1.191
MPO myeloperoxidase 1.17206
CLC Charcot-Leyden crystal galectin 1.14645
CCL7 chemokine (C-C motif) ligand 7 1.12994
TSLP thymic stromal lymphopoietin 1.11435
CCL22 chemokine (C-C motif) ligand 22 1.11183
ETV6 ets variant 6 1.08915
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 1.08412
CCL26 chemokine (C-C motif) ligand 26 1.08202
ICAM1 intercellular adhesion molecule 1 1.06312
DOCK8 dedicator of cytokinesis 8 1.03872
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.03114
CD86 CD86 molecule 1.02819
ALB albumin 1.02102
CCL5 chemokine (C-C motif) ligand 5 1.01385
TGFB1 transforming growth factor, beta 1 0.994861
IL5RA interleukin 5 receptor, alpha 0.993596
TNF tumor necrosis factor 0.978426
IL9 interleukin 9 0.968341
PDE4A phosphodiesterase 4A, cAMP-specific 0.964148
ALPPL2 alkaline phosphatase, placental-like 2 0.95745
ALPP alkaline phosphatase, placental 0.957033
ALPL alkaline phosphatase, liver/bone/kidney 0.956196
HSPG2 heparan sulfate proteoglycan 2 0.917611
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.904032
CHIA chitinase, acidic 0.895
CD69 CD69 molecule 0.890488
CCL3 chemokine (C-C motif) ligand 3 0.876148
TSPO translocator protein (18kDa) 0.874919
CRP C-reactive protein, pentraxin-related 0.872053
TBX21 T-box 21 0.871643
RCL1 RNA terminal phosphate cyclase-like 1 0.869596
NELFCD negative elongation factor complex member C/D 0.863046
IL33R interleukin 33 receptor 0.86018
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.85404
TSLIG1 tRNA splicing ligase complex subunit 1 0.847488
TLCD2 TLC domain containing 2 0.847488
CD80 CD80 molecule 0.834788
SFTPA2 surfactant protein A2 0.816334
SIGLEC8 sialic acid binding Ig-like lectin 8 0.816334
TLR2 toll-like receptor 2 0.800744
LGALS9 lectin, galactoside-binding, soluble, 9 0.795821
PRTN3 proteinase 3 0.794591
SFTPD surfactant protein D 0.791721
CD34 CD34 molecule 0.783936
JAK2 Janus kinase 2 0.765943
IL2RA interleukin 2 receptor, alpha 0.765535
POMC proopiomelanocortin 0.748424
ARG1 arginase 1 0.747204
RAG1 recombination activating gene 1 0.739894
TLR4 toll-like receptor 4 0.733406
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.731786
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.728952
HELT helt bHLH transcription factor 0.728547
IDO1 indoleamine 2,3-dioxygenase 1 0.724907
IFNA1 interferon, alpha 1 0.710378
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.703536
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.701124
GPR65 G protein-coupled receptor 65 0.698313
IL1B interleukin 1, beta 0.697911
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.695504
CDH26 cadherin 26 0.691495
IL10 interleukin 10 0.688692
RAG2 recombination activating gene 2 0.687891
CD40 CD40 molecule, TNF receptor superfamily member 5 0.683493
MSL3 male-specific lethal 3 homolog (Drosophila) 0.673917
CCDC88C coiled-coil domain containing 88C 0.668742
CEP85L centrosomal protein 85kDa-like 0.665563
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.665166
ZMYM2 zinc finger, MYM-type 2 0.664769
CD19 CD19 molecule 0.6608
SELL selectin L 0.639463
CD68 CD68 molecule 0.634742
DTD1 D-tyrosyl-tRNA deacylase 1 0.615921
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.610838
TAC1 tachykinin, precursor 1 0.605762
HSF4 heat shock transcription factor 4 0.60342
IL4R interleukin 4 receptor 0.60147
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.60108
CCR8 chemokine (C-C motif) receptor 8 0.596792
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.592895
EPGN epithelial mitogen 0.587444
CMA1 chymase 1, mast cell 0.583163
CCL8 chemokine (C-C motif) ligand 8 0.581996
CCL2 chemokine (C-C motif) ligand 2 0.580439
CXCR3 chemokine (C-X-C motif) receptor 3 0.573439
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.568386
IL13RA1 interleukin 13 receptor, alpha 1 0.564112
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.557897
SELE selectin E 0.554791
F2 coagulation factor II (thrombin) 0.547419
MED28 mediator complex subunit 28 0.543542
TRIP11 thyroid hormone receptor interactor 11 0.542767
IL25 interleukin 25 0.542379
FN1 fibronectin 1 0.53928
SHARPIN SHANK-associated RH domain interactor 0.533088
WDR43 WD repeat domain 43 0.529222
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.528449
CXCL8 chemokine (C-X-C motif) ligand 8 0.521888
TLR9 toll-like receptor 9 0.521502
KNG1 kininogen 1 0.516879
TACR2 tachykinin receptor 2 0.513802
CD52 CD52 molecule 0.511112
TLR7 toll-like receptor 7 0.510344
FASLG Fas ligand (TNF superfamily, member 6) 0.509576
TRIM37 tripartite motif containing 37 0.508041
C5AR1 complement component 5a receptor 1 0.50689
LARS leucyl-tRNA synthetase 0.498467
FBXO8 F-box protein 8 0.490454
ALOX5 arachidonate 5-lipoxygenase 0.482084
PRF1 perforin 1 (pore forming protein) 0.481705
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.480566
CD1D CD1d molecule 0.477151
MMP9 matrix metallopeptidase 9 0.471846
NPS neuropeptide S 0.471089
CCP110 centriolar coiled coil protein 110kDa 0.458241
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.457864
CXCR2 chemokine (C-X-C motif) receptor 2 0.456732
IFNA2 interferon, alpha 2 0.456732
RETNLB resistin like beta 0.455224
CYBA cytochrome b-245, alpha polypeptide 0.446558
IKZF2 IKAROS family zinc finger 2 (Helios) 0.445805
CD33 CD33 molecule 0.437906
LYN LYN proto-oncogene, Src family tyrosine kinase 0.436026
CXCL10 chemokine (C-X-C motif) ligand 10 0.433772
TES testin LIM domain protein 0.433021
SFTPA1 surfactant protein A1 0.430768
DOK3 docking protein 3 0.427765
MRC1 mannose receptor, C type 1 0.425139
FAM21C family with sequence similarity 21, member C 0.421016
CKLF chemokine-like factor 0.419892
STAT4 signal transducer and activator of transcription 4 0.418394
CYSLTR2 cysteinyl leukotriene receptor 2 0.418019
OR13F1 olfactory receptor, family 13, subfamily F, member 1 0.412779
HRH1 histamine receptor H1 0.411283
ADAMTSL1 ADAMTS-like 1 0.394863
NCAM1 neural cell adhesion molecule 1 0.391513
NOS2 nitric oxide synthase 2, inducible 0.383337
TBXA2R thromboxane A2 receptor 0.382594
ADA adenosine deaminase 0.380739
C3AR1 complement component 3a receptor 1 0.379626
COL17A1 collagen, type XVII, alpha 1 0.375179
NMUR1 neuromedin U receptor 1 0.374438
SCGB3A2 secretoglobin, family 3A, member 2 0.374438
NAAA N-acylethanolamine acid amidase 0.372958
F8 coagulation factor VIII, procoagulant component 0.372958
AGO2 argonaute RISC catalytic component 2 0.372217
PDE4DIP phosphodiesterase 4D interacting protein 0.372217
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.370737
TNC tenascin C 0.362978
DUOXA1 dual oxidase maturation factor 1 0.362609
CCR2 chemokine (C-C motif) receptor 2 0.358183
ICOSLG inducible T-cell co-stimulator ligand 0.356341
CCL1 chemokine (C-C motif) ligand 1 0.355235
F3 coagulation factor III (thromboplastin, tissue factor) 0.354868
CBFB core-binding factor, beta subunit 0.353763
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.353395
CRLF2 cytokine receptor-like factor 2 0.352291
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.35082
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.348246
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.346409
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.345675
HLA-B major histocompatibility complex, class I, B 0.344941
GGT1 gamma-glutamyltransferase 1 0.344574
CD276 CD276 molecule 0.343106
BCR breakpoint cluster region 0.339806
CD5 CD5 molecule 0.33944
HDC histidine decarboxylase 0.339073
LTB4R2 leukotriene B4 receptor 2 0.338707
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.336144
CD40LG CD40 ligand 0.334681
MYD88 myeloid differentiation primary response 88 0.3292
PKNOX2 PBX/knotted 1 homeobox 2 0.325916
MYO18A myosin XVIIIA 0.311739
CD44 CD44 molecule (Indian blood group) 0.310652
GATA2 GATA binding protein 2 0.309566
SH2D1A SH2 domain containing 1A 0.308842
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.307033
SOCS3 suppressor of cytokine signaling 3 0.303781
IL16 interleukin 16 0.303781
CLCA1 chloride channel accessory 1 0.300533
TXN thioredoxin 0.299092
NBPF8 neuroblastoma breakpoint family, member 8 0.298011
ANXA5 annexin A5 0.297651
IL6 interleukin 6 0.296571
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.291898
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.290462
CISH cytokine inducible SH2-containing protein 0.289386
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.286519
SPRED1 sprouty-related, EVH1 domain containing 1 0.286519
ACPP acid phosphatase, prostate 0.285444
BCL2L13 BCL2-like 13 (apoptosis facilitator) 0.28294
DPEP1 dipeptidase 1 (renal) 0.282225
SCX scleraxis basic helix-loop-helix transcription factor 0.281868
LTB4R leukotriene B4 receptor 0.275089
ACE angiotensin I converting enzyme 0.274732
LIN37 lin-37 DREAM MuvB core complex component 0.274376
BNIPL BCL2/adenovirus E1B 19kD interacting protein like 0.273664
LYZ lysozyme 0.272597
RNASEH2A ribonuclease H2, subunit A 0.267977
SYPL1 synaptophysin-like 1 0.267622
TMEM45A transmembrane protein 45A 0.266558
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.266203
NDFIP1 Nedd4 family interacting protein 1 0.266203
NCAPD3 non-SMC condensin II complex, subunit D3 0.263014
CD300LF CD300 molecule-like family member f 0.261599
IL33 interleukin 33 0.260891
ADAM28 ADAM metallopeptidase domain 28 0.259477
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.256299
CXCL2 chemokine (C-X-C motif) ligand 2 0.255946
IL15RA interleukin 15 receptor, alpha 0.255594
IL18R1 interleukin 18 receptor 1 0.255241
PDCD1LG2 programmed cell death 1 ligand 2 0.255241
ELANE elastase, neutrophil expressed 0.253479
ADAT3 adenosine deaminase, tRNA-specific 3 0.245396
PYCARD PYD and CARD domain containing 0.245046
HLA-C major histocompatibility complex, class I, C 0.240847
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.240497
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.239101
FLT3 fms-related tyrosine kinase 3 0.236312
TACR3 tachykinin receptor 3 0.235616
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.23492
GLCCI1 glucocorticoid induced 1 0.23353
CRTC1 CREB regulated transcription coactivator 1 0.23353
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.233183
PARP9 poly (ADP-ribose) polymerase family, member 9 0.229716
GFRA2 GDNF family receptor alpha 2 0.224884
CD300A CD300a molecule 0.221108
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.220081
FKBP8 FK506 binding protein 8, 38kDa 0.217693
ELP2 elongator acetyltransferase complex subunit 2 0.217012
RBMS2 RNA binding motif, single stranded interacting protein 2 0.214636
S1PR3 sphingosine-1-phosphate receptor 3 0.210925
CD38 CD38 molecule 0.210589
THY1 Thy-1 cell surface antigen 0.206913
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.20658
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.206248
PRKG2 protein kinase, cGMP-dependent, type II 0.205585
BATF3 basic leucine zipper transcription factor, ATF-like 3 0.205585
TRIM46 tripartite motif containing 46 0.204263
TIMP1 TIMP metallopeptidase inhibitor 1 0.201635
RGMA repulsive guidance molecule family member a 0.201308
PGM2 phosphoglucomutase 2 0.201308
WDR13 WD repeat domain 13 0.200982
POLK polymerase (DNA directed) kappa 0.200982
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.200006
IPO7 importin 7 0.200006
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.199681
CXCL9 chemokine (C-X-C motif) ligand 9 0.199033
NUTF2 nuclear transport factor 2 0.199033
DCLRE1C DNA cross-link repair 1C 0.198709
CSN1S1 casein alpha s1 0.198064
MAML2 mastermind-like 2 (Drosophila) 0.197099
RBBP7 retinoblastoma binding protein 7 0.196779
MT4 metallothionein 4 0.196459
PREB prolactin regulatory element binding 0.196139
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.191408
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.191097
SORD sorbitol dehydrogenase 0.189551
PLA2G5 phospholipase A2, group V 0.188938
GRB7 growth factor receptor-bound protein 7 0.188326
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 0.187113
FGFR1OP FGFR1 oncogene partner 0.18651
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.18621
CYTH1 cytohesin 1 0.18591
COL1A2 collagen, type I, alpha 2 0.183541
S1PR4 sphingosine-1-phosphate receptor 4 0.183541
BTK Bruton agammaglobulinemia tyrosine kinase 0.182666
MID1 midline 1 0.181222
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta 0.17952
LOC102724852 uncharacterized LOC102724852 0.178682
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.178403
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.177576
CD7 CD7 molecule 0.175411
RPE ribulose-5-phosphate-3-epimerase 0.174093
JUND jun D proto-oncogene 0.172799
CD9 CD9 molecule 0.171785
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.171535
HLA-DMA major histocompatibility complex, class II, DM alpha 0.170299
IL17A interleukin 17A 0.169812
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.16933
NMUR2 neuromedin U receptor 2 0.169091
VASP vasodilator-stimulated phosphoprotein 0.166544
PTGES prostaglandin E synthase 0.165874
ANXA10 annexin A10 0.164359
RUNX1 runt-related transcription factor 1 0.163729
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.162707
HBA2 hemoglobin, alpha 2 0.162306
TDO2 tryptophan 2,3-dioxygenase 0.161912
HRH4 histamine receptor H4 0.160948
GPR68 G protein-coupled receptor 68 0.160761
DUSP22 dual specificity phosphatase 22 0.160761
CPA3 carboxypeptidase A3 (mast cell) 0.160574
CCL4 chemokine (C-C motif) ligand 4 0.160203
PLAG1 pleiomorphic adenoma gene 1 0.160021
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 0.159838
YY1 YY1 transcription factor 0.15948
MAPK14 mitogen-activated protein kinase 14 0.158778
CTSS cathepsin S 0.158097
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.157765
LRRC32 leucine rich repeat containing 32 0.157602
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.146288
YBX2 Y box binding protein 2 0.144429
RBSN rabenosyn, RAB effector 0.144423
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.143933
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 0.143489
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.142777
NCF2 neutrophil cytosolic factor 2 0.142172
COL1A1 collagen, type I, alpha 1 0.142055
HNMT histamine N-methyltransferase 0.141739
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.141014
SRGN serglycin 0.140681
CTGF connective tissue growth factor 0.139959
CORT cortistatin 0.139825
RCAN1 regulator of calcineurin 1 0.139779
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.139276
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.139037
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.138308
CRH corticotropin releasing hormone 0.137629
TPH1 tryptophan hydroxylase 1 0.13742
HLA-E major histocompatibility complex, class I, E 0.137088
AQP5 aquaporin 5 0.135409
CYBB cytochrome b-245, beta polypeptide 0.135159
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.134916
MMP13 matrix metallopeptidase 13 0.134392
AQP3 aquaporin 3 (Gill blood group) 0.134008
TCHH trichohyalin 0.132959
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.132766
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.132408
S100A9 S100 calcium binding protein A9 0.131846
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.131824
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.131205
ATF3 activating transcription factor 3 0.130811
OSM oncostatin M 0.130811
SRSF1 serine/arginine-rich splicing factor 1 0.129927
CD22 CD22 molecule 0.129376
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.127987
AHR aryl hydrocarbon receptor 0.127927
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.127806
CHIT1 chitinase 1 (chitotriosidase) 0.127775
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.126991