epha2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description EPH receptor A2|This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 1969)
Similar Terms
Downloads & Tools

Genes

51 genes co-occuring with the biological term epha2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACP1 acid phosphatase 1, soluble
ACT actin-like protein (ACT) gene
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDX2 caudal type homeobox 2
CIB1 calcium and integrin binding 1 (calmyrin)
DSG1 desmoglein 1
EFNA1 ephrin-A1
EFNA2 ephrin-A2
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EPHA1 EPH receptor A1
EPHA2 EPH receptor A2
EPHA4 EPH receptor A4
EPHA7 EPH receptor A7
EPHB2 EPH receptor B2
EPHB4 EPH receptor B4
EPHB6 EPH receptor B6
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FGF2 fibroblast growth factor 2 (basic)
FOSL1 FOS-like antigen 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
ICAM2 intercellular adhesion molecule 2
IGF1R insulin-like growth factor 1 receptor
IL13RA2 interleukin 13 receptor, alpha 2
INPPL1 inositol polyphosphate phosphatase-like 1
LAMC2 laminin, gamma 2
LRP1 low density lipoprotein receptor-related protein 1
MET MET proto-oncogene, receptor tyrosine kinase
MIR141 microRNA 141
MIR200A microRNA 200a
MIR26B microRNA 26b
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RET ret proto-oncogene
RHOA ras homolog family member A
RHOG ras homolog family member G
STK11 serine/threonine kinase 11
TIAM1 T-cell lymphoma invasion and metastasis 1
TP53 tumor protein p53
VEGFA vascular endothelial growth factor A