epiandrosterone-3306 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the epiandrosterone-3306 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AKAP13 A kinase (PRKA) anchor protein 13
ALDOB aldolase B, fructose-bisphosphate
ARC activity-regulated cytoskeleton-associated protein
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
C21ORF2 chromosome 21 open reading frame 2
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP10 caspase 10, apoptosis-related cysteine peptidase
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDRT1 CMT1A duplicated region transcript 1
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLCN6 chloride channel, voltage-sensitive 6
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSNK1G1 casein kinase 1, gamma 1
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CYLD cylindromatosis (turban tumor syndrome)
DENND5B DENN/MADD domain containing 5B
EGR3 early growth response 3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETAA1 Ewing tumor-associated antigen 1
EXTL3 exostosin-like glycosyltransferase 3
FANCA Fanconi anemia, complementation group A
FGA fibrinogen alpha chain
FOXN3 forkhead box N3
GCKR glucokinase (hexokinase 4) regulator
GLRA1 glycine receptor, alpha 1
GPM6A glycoprotein M6A
GPSM3 G-protein signaling modulator 3
GSTTP1 glutathione S-transferase theta pseudogene 1
HAMP hepcidin antimicrobial peptide
HOXA10 homeobox A10
HOXA9 homeobox A9
HR hair growth associated
INSIG1 insulin induced gene 1
KAT6A K(lysine) acetyltransferase 6A
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KIAA0125 KIAA0125
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT17 keratin 17, type I
KRT83 keratin 83, type II
LECT1 leukocyte cell derived chemotaxin 1
LRP2 low density lipoprotein receptor-related protein 2
LTBP4 latent transforming growth factor beta binding protein 4
MAPK10 mitogen-activated protein kinase 10
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MED18 mediator complex subunit 18
MOBP myelin-associated oligodendrocyte basic protein
MRPS12 mitochondrial ribosomal protein S12
MZF1 myeloid zinc finger 1
N4BP3 NEDD4 binding protein 3
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCAPH2 non-SMC condensin II complex, subunit H2
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOX1 NADPH oxidase 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OVGP1 oviductal glycoprotein 1, 120kDa
PGR progesterone receptor
PHF8 PHD finger protein 8
PLCH1 phospholipase C, eta 1
PLIN2 perilipin 2
POU4F1 POU class 4 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGES prostaglandin E synthase
PTHLH parathyroid hormone-like hormone
PTK2B protein tyrosine kinase 2 beta
RAB11B RAB11B, member RAS oncogene family
RBP4 retinol binding protein 4, plasma
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHO rhodopsin
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RORC RAR-related orphan receptor C
RPS3A ribosomal protein S3A
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPRR3 small proline-rich protein 3
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRPK2 SRSF protein kinase 2
STEAP4 STEAP family member 4
STXBP5L syntaxin binding protein 5-like
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYT5 synaptotagmin V
TAGLN3 transgelin 3
TAOK1 TAO kinase 1
TBKBP1 TBK1 binding protein 1
TBX10 T-box 10
TRIM29 tripartite motif containing 29
TRIO trio Rho guanine nucleotide exchange factor
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
VPRBP Vpr (HIV-1) binding protein
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
XDH xanthine dehydrogenase
ZEB1 zinc finger E-box binding homeobox 1
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ADCY7 adenylate cyclase 7
ARL4C ADP-ribosylation factor-like 4C
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF63 chromosome 11 open reading frame 63
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CALML5 calmodulin-like 5
CBX8 chromobox homolog 8
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDK3 cyclin-dependent kinase 3
CFD complement factor D (adipsin)
CHRM3 cholinergic receptor, muscarinic 3
CORO2A coronin, actin binding protein, 2A
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CSTA cystatin A (stefin A)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DBR1 debranching RNA lariats 1
DENND1B DENN/MADD domain containing 1B
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DVL1 dishevelled segment polarity protein 1
EFNA1 ephrin-A1
EGFL7 EGF-like-domain, multiple 7
EPHA2 EPH receptor A2
EPPK1 epiplakin 1
EXOC3 exocyst complex component 3
FLT4 fms-related tyrosine kinase 4
FOXN2 forkhead box N2
FPGS folylpolyglutamate synthase
GRAMD4 GRAM domain containing 4
GSTT1 glutathione S-transferase theta 1
GTF2I general transcription factor IIi
HIST1H2AL histone cluster 1, H2al
HIST1H4D histone cluster 1, H4d
HIST2H2AA3 histone cluster 2, H2aa3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IL12RB1 interleukin 12 receptor, beta 1
INPP5J inositol polyphosphate-5-phosphatase J
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0513 KIAA0513
KLF7 Kruppel-like factor 7 (ubiquitous)
LAMB1 laminin, beta 1
LTC4S leukotriene C4 synthase
LY6D lymphocyte antigen 6 complex, locus D
LYPD3 LY6/PLAUR domain containing 3
MAP1S microtubule-associated protein 1S
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTCP1 mature T-cell proliferation 1
NCAM2 neural cell adhesion molecule 2
NDE1 nudE neurodevelopment protein 1
NEK11 NIMA-related kinase 11
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRTN neurturin
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OARD1 O-acyl-ADP-ribose deacylase 1
OLFML2A olfactomedin-like 2A
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARPBP PARP1 binding protein
PC pyruvate carboxylase
PHEX phosphate regulating endopeptidase homolog, X-linked
PKN1 protein kinase N1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PODXL2 podocalyxin-like 2
POMT2 protein-O-mannosyltransferase 2
RFTN1 raftlin, lipid raft linker 1
RHOC ras homolog family member C
RIN2 Ras and Rab interactor 2
RNF43 ring finger protein 43
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS14P3 ribosomal protein S14 pseudogene 3
RWDD3 RWD domain containing 3
SECTM1 secreted and transmembrane 1
SETD1B SET domain containing 1B
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SP1 Sp1 transcription factor
STARD3 StAR-related lipid transfer (START) domain containing 3
STRA6 stimulated by retinoic acid 6
TCTN2 tectonic family member 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRIP10 thyroid hormone receptor interactor 10
UBE2L6 ubiquitin-conjugating enzyme E2L 6
USP27X ubiquitin specific peptidase 27, X-linked
WDR91 WD repeat domain 91
XK X-linked Kx blood group
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF532 zinc finger protein 532
ZNF552 zinc finger protein 552
ZNF580 zinc finger protein 580
ZNF747 zinc finger protein 747
ZW10 zw10 kinetochore protein