epiandrosterone-4626 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the epiandrosterone-4626 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY6 adenylate cyclase 6
ADGB androglobin
ADGRG1 adhesion G protein-coupled receptor G1
AIM1L absent in melanoma 1-like
AKR1C1 aldo-keto reductase family 1, member C1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOA2 apolipoprotein A-II
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
B9D1 B9 protein domain 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
C1ORF116 chromosome 1 open reading frame 116
CCDC85C coiled-coil domain containing 85C
CDH8 cadherin 8, type 2
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNOT4 CCR4-NOT transcription complex, subunit 4
CNTNAP3B contactin associated protein-like 3B
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DMP1 dentin matrix acidic phosphoprotein 1
DOC2B double C2-like domains, beta
EMID1 EMI domain containing 1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EXOC6B exocyst complex component 6B
EYA4 EYA transcriptional coactivator and phosphatase 4
FASTKD2 FAST kinase domains 2
FAXDC2 fatty acid hydroxylase domain containing 2
FLRT2 fibronectin leucine rich transmembrane protein 2
FYB FYN binding protein
GNRHR gonadotropin-releasing hormone receptor
GPR20 G protein-coupled receptor 20
GREM1 gremlin 1, DAN family BMP antagonist
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HAPLN1 hyaluronan and proteoglycan link protein 1
HEG1 heart development protein with EGF-like domains 1
HIC2 hypermethylated in cancer 2
HIST1H4D histone cluster 1, H4d
HMOX1 heme oxygenase 1
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IL37 interleukin 37
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
KDM4B lysine (K)-specific demethylase 4B
KLK12 kallikrein-related peptidase 12
LDLR low density lipoprotein receptor
LEFTY1 left-right determination factor 1
LIPG lipase, endothelial
LOC390998 ribosomal protein L10 pseudogene
LOC399491
LTBP4 latent transforming growth factor beta binding protein 4
MANBA mannosidase, beta A, lysosomal
MAP7D3 MAP7 domain containing 3
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUC2 mucin 2, oligomeric mucus/gel-forming
NPY5R neuropeptide Y receptor Y5
NR2F6 nuclear receptor subfamily 2, group F, member 6
NUP88 nucleoporin 88kDa
PCDH1 protocadherin 1
PDE4DIP phosphodiesterase 4D interacting protein
PDGFB platelet-derived growth factor beta polypeptide
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA1A phospholipase A1 member A
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
PRMT2IP PRMT2 interacting protein
PTGDR2 prostaglandin D2 receptor 2
PTPRF protein tyrosine phosphatase, receptor type, F
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RPS3A ribosomal protein S3A
RUNX1 runt-related transcription factor 1
SAMD4A sterile alpha motif domain containing 4A
SAPCD1 suppressor APC domain containing 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SEPP1 selenoprotein P, plasma, 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIDT2 SID1 transmembrane family, member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SND1-IT1 SND1 intronic transcript 1
SPEG SPEG complex locus
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TCP11L1 t-complex 11, testis-specific-like 1
TM2D1 TM2 domain containing 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TSSK2 testis-specific serine kinase 2
VAC14 Vac14 homolog (S. cerevisiae)
ZNF219 zinc finger protein 219

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABHD17B abhydrolase domain containing 17B
ACE angiotensin I converting enzyme
ALOX12 arachidonate 12-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOLD1 apolipoprotein L domain containing 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
AXIN1 axin 1
C22ORF46 chromosome 22 open reading frame 46
CARD8 caspase recruitment domain family, member 8
CASP5 caspase 5, apoptosis-related cysteine peptidase
CBX8 chromobox homolog 8
CDADC1 cytidine and dCMP deaminase domain containing 1
CDIP1 cell death-inducing p53 target 1
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
CLIC3 chloride intracellular channel 3
COMP cartilage oligomeric matrix protein
CTSF cathepsin F
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBR1 debranching RNA lariats 1
DENND2D DENN/MADD domain containing 2D
DSPP dentin sialophosphoprotein
EFCAB2 EF-hand calcium binding domain 2
FAM13C family with sequence similarity 13, member C
FGF23 fibroblast growth factor 23
FILIP1L filamin A interacting protein 1-like
GAB2 GRB2-associated binding protein 2
HIST1H2AL histone cluster 1, H2al
HIST1H3B histone cluster 1, H3b
HIST1H3C histone cluster 1, H3c
HOXA1 homeobox A1
HOXA7 homeobox A7
HSPB6 heat shock protein, alpha-crystallin-related, B6
ICOS inducible T-cell co-stimulator
IFI44L interferon-induced protein 44-like
IFT140 intraflagellar transport 140
IL7 interleukin 7
IREB2 iron-responsive element binding protein 2
IRF1 interferon regulatory factor 1
KIAA0922 KIAA0922
KIAA1456 KIAA1456
KLF2 Kruppel-like factor 2
KRT20 keratin 20, type I
KRT31 keratin 31, type I
LOC100287590 uncharacterized LOC100287590
LRRC61 leucine rich repeat containing 61
LY6D lymphocyte antigen 6 complex, locus D
MAP3K7CL MAP3K7 C-terminal like
MBTPS2 membrane-bound transcription factor peptidase, site 2
MN1 meningioma (disrupted in balanced translocation) 1
MX1 MX dynamin-like GTPase 1
MYO1F myosin IF
NEUROD1 neuronal differentiation 1
NHLRC2 NHL repeat containing 2
NPPB natriuretic peptide B
NR1H4 nuclear receptor subfamily 1, group H, member 4
NTF3 neurotrophin 3
PCDH12 protocadherin 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDE8B phosphodiesterase 8B
PLAC8 placenta-specific 8
PLVAP plasmalemma vesicle associated protein
PRM2 protamine 2
PRSS22 protease, serine, 22
PRSS53 protease, serine, 53
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RIBC2 RIB43A domain with coiled-coils 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SCEL sciellin
SCN1B sodium channel, voltage gated, type I beta subunit
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC35F6 solute carrier family 35, member F6
SOX30 SRY (sex determining region Y)-box 30
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN2 tectonic family member 2
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM209 transmembrane protein 209
TMEM53 transmembrane protein 53
TSNAXIP1 translin-associated factor X interacting protein 1
TUBA3C tubulin, alpha 3c
YY2 YY2 transcription factor
ZFP30 ZFP30 zinc finger protein
ZNF16 zinc finger protein 16
ZNF204P zinc finger protein 204, pseudogene
ZNF286A zinc finger protein 286A
ZNF446 zinc finger protein 446
ZNF623 zinc finger protein 623
ZNF667 zinc finger protein 667