epiandrosterone-5687 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the epiandrosterone-5687 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APOE apolipoprotein E
ARTN artemin
ASCL1 achaete-scute family bHLH transcription factor 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
CALB2 calbindin 2
CC2D1A coiled-coil and C2 domain containing 1A
CCDC85B coiled-coil domain containing 85B
CCL19 chemokine (C-C motif) ligand 19
CCL27 chemokine (C-C motif) ligand 27
CDC14B cell division cycle 14B
CLCN6 chloride channel, voltage-sensitive 6
CLDN14 claudin 14
COL1A1 collagen, type I, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPN2 carboxypeptidase N, polypeptide 2
CRYBA1 crystallin, beta A1
CXCR4 chemokine (C-X-C motif) receptor 4
DDO D-aspartate oxidase
DSCAM Down syndrome cell adhesion molecule
DST dystonin
ECE1 endothelin converting enzyme 1
EFCAB11 EF-hand calcium binding domain 11
EGR3 early growth response 3
ELL2 elongation factor, RNA polymerase II, 2
ESR1 estrogen receptor 1
EVI2B ecotropic viral integration site 2B
FCMR Fc fragment of IgM receptor
FGD1 FYVE, RhoGEF and PH domain containing 1
FHIT fragile histidine triad
FRMPD1 FERM and PDZ domain containing 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAMT guanidinoacetate N-methyltransferase
GJB3 gap junction protein, beta 3, 31kDa
GLS glutaminase
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPR39 G protein-coupled receptor 39
GSN gelsolin
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HOXA10 homeobox A10
IFI27 interferon, alpha-inducible protein 27
IFITM1 interferon induced transmembrane protein 1
INE1 inactivation escape 1 (non-protein coding)
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRAK3 interleukin-1 receptor-associated kinase 3
IRS2 insulin receptor substrate 2
ISG15 ISG15 ubiquitin-like modifier
ITM2A integral membrane protein 2A
KCNIP1 Kv channel interacting protein 1
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KLK13 kallikrein-related peptidase 13
KSR1 kinase suppressor of ras 1
LARP7 La ribonucleoprotein domain family, member 7
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMCH1 LIM and calponin homology domains 1
LIMK2 LIM domain kinase 2
LMX1B LIM homeobox transcription factor 1, beta
MAGEA8 melanoma antigen family A8
MOBP myelin-associated oligodendrocyte basic protein
N4BP2L1 NEDD4 binding protein 2-like 1
NID1 nidogen 1
NMT1 N-myristoyltransferase 1
NPR1 natriuretic peptide receptor 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PEAK1 pseudopodium-enriched atypical kinase 1
PGLYRP1 peptidoglycan recognition protein 1
PLSCR3 phospholipid scramblase 3
PLXNB3 plexin B3
PON1 paraoxonase 1
PTCRA pre T-cell antigen receptor alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RTEL1 regulator of telomere elongation helicase 1
RUFY3 RUN and FYVE domain containing 3
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SOX11 SRY (sex determining region Y)-box 11
TAPBPL TAP binding protein-like
TBC1D2B TBC1 domain family, member 2B
TDRKH tudor and KH domain containing
TMPRSS6 transmembrane protease, serine 6
TOP3A topoisomerase (DNA) III alpha
TPMT thiopurine S-methyltransferase
VN1R1 vomeronasal 1 receptor 1
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
ZNF154 zinc finger protein 154
ZNF3 zinc finger protein 3

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMCX2 armadillo repeat containing, X-linked 2
ATP10D ATPase, class V, type 10D
BAG4 BCL2-associated athanogene 4
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CARD8 caspase recruitment domain family, member 8
CBX4 chromobox homolog 4
CCDC132 coiled-coil domain containing 132
CCP110 centriolar coiled coil protein 110kDa
CD82 CD82 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CFD complement factor D (adipsin)
CGREF1 cell growth regulator with EF-hand domain 1
CIC capicua transcriptional repressor
CLSPN claspin
CNGB3 cyclic nucleotide gated channel beta 3
CXORF21 chromosome X open reading frame 21
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOCK1 dedicator of cytokinesis 1
DRD1 dopamine receptor D1
ECHDC3 enoyl CoA hydratase domain containing 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBRS fibrosin
FLT4 fms-related tyrosine kinase 4
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GBP2 guanylate binding protein 2, interferon-inducible
GLS2 glutaminase 2 (liver, mitochondrial)
GPR19 G protein-coupled receptor 19
HHLA3 HERV-H LTR-associating 3
HIST1H1D histone cluster 1, H1d
HIST1H2AI histone cluster 1, H2ai
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IRF2 interferon regulatory factor 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDM8 lysine (K)-specific demethylase 8
KLF7 Kruppel-like factor 7 (ubiquitous)
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LARP6 La ribonucleoprotein domain family, member 6
LAX1 lymphocyte transmembrane adaptor 1
LONRF3 LON peptidase N-terminal domain and ring finger 3
LY6D lymphocyte antigen 6 complex, locus D
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MGC12488
MITF microphthalmia-associated transcription factor
MXD3 MAX dimerization protein 3
N4BP3 NEDD4 binding protein 3
NEK11 NIMA-related kinase 11
NUP62CL nucleoporin 62kDa C-terminal like
OCA2 oculocutaneous albinism II
PACS1 phosphofurin acidic cluster sorting protein 1
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PITX2 paired-like homeodomain 2
PRSS16 protease, serine, 16 (thymus)
PTK6 protein tyrosine kinase 6
RAB3D RAB3D, member RAS oncogene family
RIN2 Ras and Rab interactor 2
RPGR retinitis pigmentosa GTPase regulator
S100A9 S100 calcium binding protein A9
SCG2 secretogranin II
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SH2D4A SH2 domain containing 4A
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC46A3 solute carrier family 46, member 3
SLMO1 slowmo homolog 1 (Drosophila)
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SP1 Sp1 transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
STARD3 StAR-related lipid transfer (START) domain containing 3
TGFBR3 transforming growth factor, beta receptor III
TMEM19 transmembrane protein 19
TMEM209 transmembrane protein 209
TRAIP TRAF interacting protein
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUBG2 tubulin, gamma 2
VAX2 ventral anterior homeobox 2
VGF VGF nerve growth factor inducible
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB48 zinc finger and BTB domain containing 48
ZC3H3 zinc finger CCCH-type containing 3
ZNF211 zinc finger protein 211
ZNF280D zinc finger protein 280D
ZNF428 zinc finger protein 428
ZNF862 zinc finger protein 862