epidermal growth factor receptor signaling pathway Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0007173)
External Link http://amigo.geneontology.org/amigo/term/GO_0007173
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Genes

46 genes participating in the epidermal growth factor receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
AKT1 v-akt murine thymoma viral oncogene homolog 1
AREG amphiregulin
BCAR1 breast cancer anti-estrogen resistance 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTC betacellulin
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
DGKD diacylglycerol kinase, delta 130kDa
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EPGN epithelial mitogen
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBIN erbb2 interacting protein
EREG epiregulin
FAM83A family with sequence similarity 83, member A
FAM83B family with sequence similarity 83, member B
FAM83C family with sequence similarity 83, member C
GAB1 GRB2-associated binding protein 1
GAREM1 GRB2 associated regulator of MAPK1 subtype 1
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
HBEGF heparin-binding EGF-like growth factor
IQGAP1 IQ motif containing GTPase activating protein 1
KIF16B kinesin family member 16B
NCK2 NCK adaptor protein 2
PDPK1 3-phosphoinositide dependent protein kinase 1
PIGR polymeric immunoglobulin receptor
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLCE1 phospholipase C, epsilon 1
PLCG1 phospholipase C, gamma 1
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
REPS2 RALBP1 associated Eps domain containing 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SLC30A10 solute carrier family 30, member 10
SOS1 son of sevenless homolog 1 (Drosophila)
SOX9 SRY (sex determining region Y)-box 9
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TDGF1 teratocarcinoma-derived growth factor 1
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
VIL1 villin 1