epidermis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The outer epithelial layer of the external integument of the animal body that is derived from the embryonic epiblast; specifically: the outer nonsensitive and nonvascular layer of the skin of a vertebrate that overlies the dermis. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000404)
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Genes

232 genes co-occuring with the biological term epidermis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2ML1 alpha-2-macroglobulin-like 1
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACSL5 acyl-CoA synthetase long-chain family member 5
ADRB2 adrenoceptor beta 2, surface
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AIM2 absent in melanoma 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA9 annexin A9
AQP3 aquaporin 3 (Gill blood group)
AREG amphiregulin
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BAX BCL2-associated X protein
BCHE butyrylcholinesterase
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BTC betacellulin
CALML3 calmodulin-like 3
CALML5 calmodulin-like 5
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCHCR1 coiled-coil alpha-helical rod protein 1
CCL17 chemokine (C-C motif) ligand 17
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL27 chemokine (C-C motif) ligand 27
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCR3 chemokine (C-C motif) receptor 3
CD1A CD1a molecule
CD207 CD207 molecule, langerin
CD36 CD36 molecule (thrombospondin receptor)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD44 CD44 molecule (Indian blood group)
CD99 CD99 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDSN corneodesmosin
CFL1 cofilin 1 (non-muscle)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHUK conserved helix-loop-helix ubiquitous kinase
CLDN1 claudin 1
CLEC7A C-type lectin domain family 7, member A
COL17A1 collagen, type XVII, alpha 1
CSPG4 chondroitin sulfate proteoglycan 4
CST6 cystatin E/M
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSL cathepsin L
CTSV cathepsin V
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DANCR differentiation antagonizing non-protein coding RNA
DDIT3 DNA-damage-inducible transcript 3
DEFB1 defensin, beta 1
DEFB103B defensin, beta 103B
DEFB4A defensin, beta 4A
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DSC1 desmocollin 1
DSG1 desmoglein 1
DSG4 desmoglein 4
DSTN destrin (actin depolymerizing factor)
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EGFR epidermal growth factor receptor
EPAS1 endothelial PAS domain protein 1
EPHA1 EPH receptor A1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
EREG epiregulin
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FLG filaggrin
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXE1 forkhead box E1
FURIN furin (paired basic amino acid cleaving enzyme)
GAP43 growth associated protein 43
GAS6 growth arrest-specific 6
GLIS1 GLIS family zinc finger 1
GPER1 G protein-coupled estrogen receptor 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
HBEGF heparin-binding EGF-like growth factor
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HOXB4 homeobox B4
HRNR hornerin
HSPB1 heat shock 27kDa protein 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
IHH indian hedgehog
IL10 interleukin 10
IL13 interleukin 13
IL18R1 interleukin 18 receptor 1
IL1A interleukin 1, alpha
IL20 interleukin 20
IL22 interleukin 22
IL24 interleukin 24
IL33 interleukin 33
IRF3 interferon regulatory factor 3
IVL involucrin
JUP junction plakoglobin
KDR kinase insert domain receptor
KLF4 Kruppel-like factor 4 (gut)
KLK5 kallikrein-related peptidase 5
KLK7 kallikrein-related peptidase 7
KRT1 keratin 1, type II
KRT10 keratin 10, type I
KRT14 keratin 14, type I
KRT19 keratin 19, type I
KRT5 keratin 5, type II
KRT79 keratin 79, type II
KRT9 keratin 9, type I
LAMA3 laminin, alpha 3
LAMC2 laminin, gamma 2
LCN2 lipocalin 2
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS7 lectin, galactoside-binding, soluble, 7
LGI3 leucine-rich repeat LGI family, member 3
LOR loricrin
LRP1 low density lipoprotein receptor-related protein 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK8 mitogen-activated protein kinase 8
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR146A microRNA 146a
MIR21 microRNA 21
MIR449A microRNA 449a
MMP1 matrix metallopeptidase 1
MMP19 matrix metallopeptidase 19
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NES nestin
NFE2L2 nuclear factor, erythroid 2-like 2
NGF nerve growth factor (beta polypeptide)
NIPAL4 NIPA-like domain containing 4
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NQO1 NAD(P)H dehydrogenase, quinone 1
NRP1 neuropilin 1
NRP2 neuropilin 2
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OGG1 8-oxoguanine DNA glycosylase
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OPN1MW2 opsin 1 (cone pigments), medium-wave-sensitive 2
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
ORAI1 ORAI calcium release-activated calcium modulator 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PADI4 peptidyl arginine deiminase, type IV
PDGFB platelet-derived growth factor beta polypeptide
PDPN podoplanin
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKP1 plakophilin 1
PLB1 phospholipase B1
POF1B premature ovarian failure, 1B
PPARD peroxisome proliferator-activated receptor delta
PPL periplakin
PSORS4 psoriasis susceptibility 4
PSPH phosphoserine phosphatase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
PTTG1 pituitary tumor-transforming 1
RAB10 RAB10, member RAS oncogene family
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RHO rhodopsin
RHOD ras homolog family member D
RNASE7 ribonuclease, RNase A family, 7
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SDC1 syndecan 1
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SHH sonic hedgehog
SIRT6 sirtuin 6
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLURP1 secreted LY6/PLAUR domain containing 1
SOD2 superoxide dismutase 2, mitochondrial
SPINK5 serine peptidase inhibitor, Kazal type 5
SPINK6 serine peptidase inhibitor, Kazal type 6
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TCHHL1 trichohyalin-like 1
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM1 transglutaminase 1
TGM3 transglutaminase 3
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53
TP63 tumor protein p63
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TSLP thymic stromal lymphopoietin
TXNIP thioredoxin interacting protein
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VEGFA vascular endothelial growth factor A
WNT3A wingless-type MMTV integration site family, member 3A
YY1 YY1 transcription factor