epirizole-1681 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the epirizole-1681 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANKMY1 ankyrin repeat and MYND domain containing 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATAT1 alpha tubulin acetyltransferase 1
CA4 carbonic anhydrase IV
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD83 CD83 molecule
CNGB3 cyclic nucleotide gated channel beta 3
COMMD4 COMM domain containing 4
CPNE7 copine VII
CTSZ cathepsin Z
CYHR1 cysteine/histidine-rich 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR1 estrogen receptor 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FBXL7 F-box and leucine-rich repeat protein 7
FDPS farnesyl diphosphate synthase
FN1 fibronectin 1
FURIN furin (paired basic amino acid cleaving enzyme)
GAL galanin/GMAP prepropeptide
GAMT guanidinoacetate N-methyltransferase
GAS7 growth arrest-specific 7
GMPR guanosine monophosphate reductase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH4 G patch domain containing 4
GPR137 G protein-coupled receptor 137
GPR27 G protein-coupled receptor 27
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRK harakiri, BCL2 interacting protein
HYAL3 hyaluronoglucosaminidase 3
IFNA14 interferon, alpha 14
IKZF4 IKAROS family zinc finger 4 (Eos)
IL2 interleukin 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KLF9 Kruppel-like factor 9
LAMB4 laminin, beta 4
LOC100131510 uncharacterized LOC100131510
LTB lymphotoxin beta (TNF superfamily, member 3)
MAN2A2 mannosidase, alpha, class 2A, member 2
MAPK8 mitogen-activated protein kinase 8
MPPED2 metallophosphoesterase domain containing 2
NAIP NLR family, apoptosis inhibitory protein
NF1 neurofibromin 1
NMT2 N-myristoyltransferase 2
NOP16 NOP16 nucleolar protein
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
ORC5 origin recognition complex, subunit 5
PCDHB13 protocadherin beta 13
PICALM phosphatidylinositol binding clathrin assembly protein
PLSCR4 phospholipid scramblase 4
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKCQ protein kinase C, theta
PTGDR2 prostaglandin D2 receptor 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
QPCTL glutaminyl-peptide cyclotransferase-like
RAB28 RAB28, member RAS oncogene family
RANBP3 RAN binding protein 3
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RGS10 regulator of G-protein signaling 10
RGS14 regulator of G-protein signaling 14
RGS20 regulator of G-protein signaling 20
RNF126P1 ring finger protein 126 pseudogene 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SAFB scaffold attachment factor B
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SETD1A SET domain containing 1A
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIK3 SIK family kinase 3
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SMAD3 SMAD family member 3
SNW1 SNW domain containing 1
STRN striatin, calmodulin binding protein
SYN2 synapsin II
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TET3 tet methylcytosine dioxygenase 3
THBS3 thrombospondin 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM80 transmembrane protein 80
TWF1 twinfilin actin binding protein 1
UBXN1 UBX domain protein 1
VPS9D1 VPS9 domain containing 1
WFDC2 WAP four-disulfide core domain 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF134 zinc finger protein 134
ZNF350 zinc finger protein 350
ZNF646 zinc finger protein 646
ZNF747 zinc finger protein 747
ZNF770 zinc finger protein 770

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BRD1 bromodomain containing 1
C14ORF132 chromosome 14 open reading frame 132
C6ORF47 chromosome 6 open reading frame 47
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAMTA2 calmodulin binding transcription activator 2
CHKB choline kinase beta
CIC capicua transcriptional repressor
CISH cytokine inducible SH2-containing protein
CLASP1 cytoplasmic linker associated protein 1
CLDN15 claudin 15
COL4A5 collagen, type IV, alpha 5
COQ6 coenzyme Q6 monooxygenase
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DENND4A DENN/MADD domain containing 4A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAAF2 dynein, axonemal, assembly factor 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLJ22184
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GDI1 GDP dissociation inhibitor 1
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GNPDA1 glucosamine-6-phosphate deaminase 1
GPR19 G protein-coupled receptor 19
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H2AE histone cluster 1, H2ae
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KLF3 Kruppel-like factor 3 (basic)
KRBOX4 KRAB box domain containing 4
LIG1 ligase I, DNA, ATP-dependent
LNPEP leucyl/cystinyl aminopeptidase
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC8E leucine rich repeat containing 8 family, member E
LZTFL1 leucine zipper transcription factor-like 1
LZTR1 leucine-zipper-like transcription regulator 1
MAP1S microtubule-associated protein 1S
MAP7D1 MAP7 domain containing 1
METTL4 methyltransferase like 4
MFSD11 major facilitator superfamily domain containing 11
MNX1 motor neuron and pancreas homeobox 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTHFSD methenyltetrahydrofolate synthetase domain containing
NBEAL2 neurobeachin-like 2
NDRG1 N-myc downstream regulated 1
PARD6A par-6 family cell polarity regulator alpha
PISD phosphatidylserine decarboxylase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLXNA3 plexin A3
PNPLA6 patatin-like phospholipase domain containing 6
PROCR protein C receptor, endothelial
PTBP2 polypyrimidine tract binding protein 2
PTK6 protein tyrosine kinase 6
PTPRU protein tyrosine phosphatase, receptor type, U
RABL3 RAB, member of RAS oncogene family-like 3
RAD54L RAD54-like (S. cerevisiae)
RARS arginyl-tRNA synthetase
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
REEP4 receptor accessory protein 4
RNF170 ring finger protein 170
RP2 retinitis pigmentosa 2 (X-linked recessive)
SCAMP3 secretory carrier membrane protein 3
SCPEP1 serine carboxypeptidase 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2D4A SH2 domain containing 4A
SIDT1 SID1 transmembrane family, member 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SPIDR scaffolding protein involved in DNA repair
SSFA2 sperm specific antigen 2
STBD1 starch binding domain 1
TBC1D12 TBC1 domain family, member 12
THAP1 THAP domain containing, apoptosis associated protein 1
TMEM120B transmembrane protein 120B
TMEM127 transmembrane protein 127
TMEM2 transmembrane protein 2
TMOD3 tropomodulin 3 (ubiquitous)
TPST2 tyrosylprotein sulfotransferase 2
TPTE transmembrane phosphatase with tensin homology
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
VASH1 vasohibin 1
WBP2 WW domain binding protein 2
WDR18 WD repeat domain 18
WDR7 WD repeat domain 7
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF180 zinc finger protein 180
ZNF184 zinc finger protein 184
ZNF318 zinc finger protein 318
ZNF432 zinc finger protein 432
ZNF573 zinc finger protein 573