| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the epirizole-1803 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ASF1A | anti-silencing function 1A histone chaperone |
| ATM | ATM serine/threonine kinase |
| ATP10D | ATPase, class V, type 10D |
| BCL6 | B-cell CLL/lymphoma 6 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CBX8 | chromobox homolog 8 |
| CCNA1 | cyclin A1 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDC5L | cell division cycle 5-like |
| CDV3 | CDV3 homolog (mouse) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CUL4B | cullin 4B |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DPP4 | dipeptidyl-peptidase 4 |
| EML4 | echinoderm microtubule associated protein like 4 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FAM175B | family with sequence similarity 175, member B |
| FH | fumarate hydratase |
| FSCN1 | fascin actin-bundling protein 1 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| H1F0 | H1 histone family, member 0 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| IMPACT | impact RWD domain protein |
| ING4 | inhibitor of growth family, member 4 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| JAK2 | Janus kinase 2 |
| KIAA1549L | KIAA1549-like |
| LARGE | like-glycosyltransferase |
| LEPROT | leptin receptor overlapping transcript |
| LIMK2 | LIM domain kinase 2 |
| LIN7C | lin-7 homolog C (C. elegans) |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MAT2A | methionine adenosyltransferase II, alpha |
| MBNL1 | muscleblind-like splicing regulator 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MECP2 | methyl CpG binding protein 2 |
| MED6 | mediator complex subunit 6 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MFN2 | mitofusin 2 |
| MTMR2 | myotubularin related protein 2 |
| NCKAP1 | NCK-associated protein 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NEK2 | NIMA-related kinase 2 |
| NNT | nicotinamide nucleotide transhydrogenase |
| NOL12 | nucleolar protein 12 |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PAPOLA | poly(A) polymerase alpha |
| PCNX | pecanex homolog (Drosophila) |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PEX1 | peroxisomal biogenesis factor 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRPF4B | pre-mRNA processing factor 4B |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) |
| RARS | arginyl-tRNA synthetase |
| RDX | radixin |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| RSRP1 | arginine/serine-rich protein 1 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SETD6 | SET domain containing 6 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STOM | stomatin |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TMCO1 | transmembrane and coiled-coil domains 1 |
| TMEM194A | transmembrane protein 194A |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TPD52 | tumor protein D52 |
| TRAIP | TRAF interacting protein |
| UBE3B | ubiquitin protein ligase E3B |
| USP34 | ubiquitin specific peptidase 34 |
| VAMP4 | vesicle-associated membrane protein 4 |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| ZNF358 | zinc finger protein 358 |
| ZNF415 | zinc finger protein 415 |
| ZNF551 | zinc finger protein 551 |
| ZXDC | ZXD family zinc finger C |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| APH1B | APH1B gamma secretase subunit |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CAPN15 | calpain 15 |
| CCDC85C | coiled-coil domain containing 85C |
| CDIP1 | cell death-inducing p53 target 1 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHKB | choline kinase beta |
| CHMP7 | charged multivesicular body protein 7 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CST4 | cystatin S |
| CUEDC1 | CUE domain containing 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| EFNA3 | ephrin-A3 |
| EFNB1 | ephrin-B1 |
| FA2H | fatty acid 2-hydroxylase |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FUZ | fuzzy planar cell polarity protein |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| HDAC7 | histone deacetylase 7 |
| HIST1H3B | histone cluster 1, H3b |
| HLX | H2.0-like homeobox |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFLR1 | IGF-like family receptor 1 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KDM4D | lysine (K)-specific demethylase 4D |
| KIFC3 | kinesin family member C3 |
| KRT4 | keratin 4, type II |
| LAMC3 | laminin, gamma 3 |
| LOC730101 | uncharacterized LOC730101 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC61 | leucine rich repeat containing 61 |
| MAGEF1 | melanoma antigen family F1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MED9 | mediator complex subunit 9 |
| MTMR12 | myotubularin related protein 12 |
| MX1 | MX dynamin-like GTPase 1 |
| MXD3 | MAX dimerization protein 3 |
| MYL5 | myosin, light chain 5, regulatory |
| NRTN | neurturin |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARD6A | par-6 family cell polarity regulator alpha |
| PC | pyruvate carboxylase |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMCH | pro-melanin-concentrating hormone |
| PRSS8 | protease, serine, 8 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RIN1 | Ras and Rab interactor 1 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SIRT2 | sirtuin 2 |
| SIX1 | SIX homeobox 1 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SMA4 | glucuronidase, beta pseudogene |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPATA2L | spermatogenesis associated 2-like |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TUBA1C | tubulin, alpha 1c |
| UNC119 | unc-119 homolog (C. elegans) |
| URM1 | ubiquitin related modifier 1 |
| USB1 | U6 snRNA biogenesis 1 |
| USP18 | ubiquitin specific peptidase 18 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF219 | zinc finger protein 219 |
| ZNF282 | zinc finger protein 282 |
| ZNF385D | zinc finger protein 385D |
| ZNF747 | zinc finger protein 747 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF85 | zinc finger protein 85 |
| ZNF862 | zinc finger protein 862 |