epirizole-5995 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the epirizole-5995 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACBD4 acyl-CoA binding domain containing 4
ACOX2 acyl-CoA oxidase 2, branched chain
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ATP9A ATPase, class II, type 9A
C1ORF54 chromosome 1 open reading frame 54
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCL13 chemokine (C-C motif) ligand 13
CDHR2 cadherin-related family member 2
CELA3A chymotrypsin-like elastase family, member 3A
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLPS colipase, pancreatic
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DFNA5 deafness, autosomal dominant 5
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EPHB2 EPH receptor B2
FAM184A family with sequence similarity 184, member A
FRMD8 FERM domain containing 8
GAS7 growth arrest-specific 7
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPR21 G protein-coupled receptor 21
GYPB glycophorin B (MNS blood group)
H2AFY2 H2A histone family, member Y2
HAP1 huntingtin-associated protein 1
HCRP1 hepatocellular carcinoma-related HCRP1
HIPK3 homeodomain interacting protein kinase 3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXA6 homeobox A6
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
IBSP integrin-binding sialoprotein
IDUA iduronidase, alpha-L-
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
INHBE inhibin, beta E
IPW imprinted in Prader-Willi syndrome (non-protein coding)
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIF13A kinesin family member 13A
KLF12 Kruppel-like factor 12
KLF13 Kruppel-like factor 13
KLHL24 kelch-like family member 24
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LDB3 LIM domain binding 3
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LTBP4 latent transforming growth factor beta binding protein 4
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MX2 MX dynamin-like GTPase 2
MXD4 MAX dimerization protein 4
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYO15A myosin XVA
MYRIP myosin VIIA and Rab interacting protein
NCOR2 nuclear receptor corepressor 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOVA2 neuro-oncological ventral antigen 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ONECUT2 one cut homeobox 2
PCDHB8 protocadherin beta 8
PHEX phosphate regulating endopeptidase homolog, X-linked
PHF1 PHD finger protein 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PTK6 protein tyrosine kinase 6
RB1 retinoblastoma 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFTN1 raftlin, lipid raft linker 1
RPL5 ribosomal protein L5
RPL7 ribosomal protein L7
SCN3A sodium channel, voltage gated, type III alpha subunit
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIPA1 signal-induced proliferation-associated 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNTA1 syntrophin, alpha 1
SPPL2B signal peptide peptidase like 2B
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STAB2 stabilin 2
STK24 serine/threonine kinase 24
SUGP1 SURP and G patch domain containing 1
TBKBP1 TBK1 binding protein 1
TBX6 T-box 6
TESC tescalcin
TEX15 testis expressed 15
TPMT thiopurine S-methyltransferase
TRIM21 tripartite motif containing 21
UCN urocortin
WLS wntless Wnt ligand secretion mediator
WNT16 wingless-type MMTV integration site family, member 16
WNT5A wingless-type MMTV integration site family, member 5A
ZNF419 zinc finger protein 419
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADGRG2 adhesion G protein-coupled receptor G2
AMH anti-Mullerian hormone
AMT aminomethyltransferase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
C16ORF45 chromosome 16 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN5 calpain 5
CD3EAP CD3e molecule, epsilon associated protein
CDK20 cyclin-dependent kinase 20
CGREF1 cell growth regulator with EF-hand domain 1
CIDEC cell death-inducing DFFA-like effector c
CPPED1 calcineurin-like phosphoesterase domain containing 1
CSF1R colony stimulating factor 1 receptor
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DNM1 dynamin 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
DSPP dentin sialophosphoprotein
FAM110B family with sequence similarity 110, member B
FAM131A family with sequence similarity 131, member A
FCHO1 FCH domain only 1
FGF23 fibroblast growth factor 23
FGL1 fibrinogen-like 1
GBP2 guanylate binding protein 2, interferon-inducible
GLTSCR1 glioma tumor suppressor candidate region gene 1
GRTP1 growth hormone regulated TBC protein 1
HIST1H4F histone cluster 1, H4f
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXA4 homeobox A4
HOXD11 homeobox D11
HPN hepsin
IFT140 intraflagellar transport 140
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INO80D INO80 complex subunit D
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IREB2 iron-responsive element binding protein 2
JMJD4 jumonji domain containing 4
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0125 KIAA0125
KIAA0319L KIAA0319-like
KREMEN2 kringle containing transmembrane protein 2
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIN7A lin-7 homolog A (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP9 microtubule-associated protein 9
MOCS3 molybdenum cofactor synthesis 3
NDE1 nudE neurodevelopment protein 1
NDRG1 N-myc downstream regulated 1
NXPH4 neurexophilin 4
OXTR oxytocin receptor
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHA6 protocadherin alpha 6
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLH polymerase (DNA directed), eta
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
ROM1 retinal outer segment membrane protein 1
S100A4 S100 calcium binding protein A4
SCN1B sodium channel, voltage gated, type I beta subunit
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SIRT6 sirtuin 6
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SOX12 SRY (sex determining region Y)-box 12
SPRYD7 SPRY domain containing 7
SREK1IP1 SREK1-interacting protein 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TET3 tet methylcytosine dioxygenase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM120B transmembrane protein 120B
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VASH1 vasohibin 1
VASH2 vasohibin 2
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
WFDC2 WAP four-disulfide core domain 2
YEATS2 YEATS domain containing 2
ZBTB22 zinc finger and BTB domain containing 22
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF365 zinc finger protein 365
ZNF408 zinc finger protein 408
ZNF492 zinc finger protein 492