epitiostanol-2922 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the epitiostanol-2922 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACACB acetyl-CoA carboxylase beta
ACVR1B activin A receptor, type IB
ADGRB1 adhesion G protein-coupled receptor B1
ADTRP androgen-dependent TFPI-regulating protein
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APOL3 apolipoprotein L, 3
ARMC6 armadillo repeat containing 6
ATF7 activating transcription factor 7
BTBD7 BTB (POZ) domain containing 7
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAV2 caveolin 2
CCR4 chemokine (C-C motif) receptor 4
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CENPO centromere protein O
CLEC4A C-type lectin domain family 4, member A
CLIP2 CAP-GLY domain containing linker protein 2
CLTC clathrin, heavy chain (Hc)
CORT cortistatin
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDAH2 dimethylarginine dimethylaminohydrolase 2
DMD dystrophin
DUSP4 dual specificity phosphatase 4
DZIP3 DAZ interacting zinc finger protein 3
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL7 F-box and leucine-rich repeat protein 7
FGF23 fibroblast growth factor 23
FGFR1 fibroblast growth factor receptor 1
FN1 fibronectin 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GLP1R glucagon-like peptide 1 receptor
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GSDMD gasdermin D
HDAC6 histone deacetylase 6
HIST1H2AK histone cluster 1, H2ak
HRASLS2 HRAS-like suppressor 2
IFNA16 interferon, alpha 16
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP7 insulin-like growth factor binding protein 7
INE1 inactivation escape 1 (non-protein coding)
INHBA inhibin, beta A
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LMNA lamin A/C
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAPK8 mitogen-activated protein kinase 8
MET MET proto-oncogene, receptor tyrosine kinase
METRN meteorin, glial cell differentiation regulator
MLPH melanophilin
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYH14 myosin, heavy chain 14, non-muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCKIPSD NCK interacting protein with SH3 domain
NCS1 neuronal calcium sensor 1
NECAB2 N-terminal EF-hand calcium binding protein 2
NLE1 notchless homolog 1 (Drosophila)
NPFFR1 neuropeptide FF receptor 1
NUPR1 nuclear protein, transcriptional regulator, 1
ONECUT2 one cut homeobox 2
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PDE4C phosphodiesterase 4C, cAMP-specific
PDLIM7 PDZ and LIM domain 7 (enigma)
PHF20L1 PHD finger protein 20-like 1
PKD2L2 polycystic kidney disease 2-like 2
PLSCR3 phospholipid scramblase 3
PLXNB1 plexin B1
PODXL2 podocalyxin-like 2
POU5F1B POU class 5 homeobox 1B
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRB1 proline-rich protein BstNI subfamily 1
PRX periaxin
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PXN paxillin
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RETN resistin
RIBC2 RIB43A domain with coiled-coils 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RSU1 Ras suppressor protein 1
RUNX1 runt-related transcription factor 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SELPLG selectin P ligand
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
TAOK2 TAO kinase 2
TBCD tubulin folding cofactor D
TGM2 transglutaminase 2
THAP9 THAP domain containing 9
TSPAN8 tetraspanin 8
UBE3A ubiquitin protein ligase E3A
VEZT vezatin, adherens junctions transmembrane protein
WNT16 wingless-type MMTV integration site family, member 16
ZER1 zyg-11 related, cell cycle regulator
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALS2CL ALS2 C-terminal like
AMT aminomethyltransferase
ANAPC2 anaphase promoting complex subunit 2
BAMBI BMP and activin membrane-bound inhibitor
BCORL1 BCL6 corepressor-like 1
BIRC3 baculoviral IAP repeat containing 3
BRIX1 BRX1, biogenesis of ribosomes
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COL15A1 collagen, type XV, alpha 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DEPTOR DEP domain containing MTOR-interacting protein
DNAAF2 dynein, axonemal, assembly factor 2
DNAL4 dynein, axonemal, light chain 4
DOLK dolichol kinase
DOLPP1 dolichyldiphosphatase 1
DSE dermatan sulfate epimerase
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGR2 early growth response 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC6 excision repair cross-complementation group 6
FAM53B family with sequence similarity 53, member B
FJX1 four jointed box 1 (Drosophila)
FKBP14 FK506 binding protein 14, 22 kDa
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GDAP1 ganglioside induced differentiation associated protein 1
GEMIN8 gem (nuclear organelle) associated protein 8
GPR27 G protein-coupled receptor 27
GRAMD1B GRAM domain containing 1B
GUSBP3 glucuronidase, beta pseudogene 3
HCAR3 hydroxycarboxylic acid receptor 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H4E histone cluster 1, H4e
HOXA1 homeobox A1
HP haptoglobin
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL18 interleukin 18
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0556 KIAA0556
LPPR3 lipid phosphate phosphatase-related protein type 3
MAK male germ cell-associated kinase
MCTP2 multiple C2 domains, transmembrane 2
MDM4 MDM4, p53 regulator
MX1 MX dynamin-like GTPase 1
MYH15 myosin, heavy chain 15
N4BP2L2-IT2 N4BPL2 intronic transcript 2
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NFE2L3 nuclear factor, erythroid 2-like 3
PADI2 peptidyl arginine deiminase, type II
PAQR4 progestin and adipoQ receptor family member IV
PARPBP PARP1 binding protein
PBX3 pre-B-cell leukemia homeobox 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PNRC1 proline-rich nuclear receptor coactivator 1
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PYGB phosphorylase, glycogen; brain
RAB17 RAB17, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOBTB2 Rho-related BTB domain containing 2
RNF121 ring finger protein 121
RPGRIP1L RPGRIP1-like
SERGEF secretion regulating guanine nucleotide exchange factor
SH3BGR SH3 domain binding glutamate-rich protein
SKI SKI proto-oncogene
SLC12A9 solute carrier family 12, member 9
SLC16A4 solute carrier family 16, member 4
SPAG4 sperm associated antigen 4
SPRYD7 SPRY domain containing 7
STIM1 stromal interaction molecule 1
STXBP1 syntaxin binding protein 1
SYCP2 synaptonemal complex protein 2
TESK1 testis-specific kinase 1
THOP1 thimet oligopeptidase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLR6 toll-like receptor 6
TMEM134 transmembrane protein 134
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TPM3 tropomyosin 3
TRPS1 trichorhinophalangeal syndrome I
TTC26 tetratricopeptide repeat domain 26
ULBP2 UL16 binding protein 2
UNC13B unc-13 homolog B (C. elegans)
USB1 U6 snRNA biogenesis 1
USP19 ubiquitin specific peptidase 19
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR91 WD repeat domain 91
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YY2 YY2 transcription factor
ZNF155 zinc finger protein 155
ZNF225 zinc finger protein 225
ZNF32 zinc finger protein 32
ZNF8 zinc finger protein 8